ES8700849A1 - Un procedimiento para la preparacion de -(p-t-butilfenil)-4-(hidroxidifenilmetil)-1-piperidinobutanol - Google Patents
Un procedimiento para la preparacion de -(p-t-butilfenil)-4-(hidroxidifenilmetil)-1-piperidinobutanolInfo
- Publication number
- ES8700849A1 ES8700849A1 ES548555A ES548555A ES8700849A1 ES 8700849 A1 ES8700849 A1 ES 8700849A1 ES 548555 A ES548555 A ES 548555A ES 548555 A ES548555 A ES 548555A ES 8700849 A1 ES8700849 A1 ES 8700849A1
- Authority
- ES
- Spain
- Prior art keywords
- hydroxidipenomethylme
- butilfenil
- piperidinobutanol
- translation
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- LQNUZADURLCDLV-UHFFFAOYSA-N nitrobenzene Chemical compound [O-][N+](=O)C1=CC=CC=C1 LQNUZADURLCDLV-UHFFFAOYSA-N 0.000 abstract 2
- YTZKOQUCBOVLHL-UHFFFAOYSA-N tert-butylbenzene Chemical compound CC(C)(C)C1=CC=CC=C1 YTZKOQUCBOVLHL-UHFFFAOYSA-N 0.000 abstract 2
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 abstract 2
- FALRKNHUBBKYCC-UHFFFAOYSA-N 2-(chloromethyl)pyridine-3-carbonitrile Chemical compound ClCC1=NC=CC=C1C#N FALRKNHUBBKYCC-UHFFFAOYSA-N 0.000 abstract 1
- 238000005727 Friedel-Crafts reaction Methods 0.000 abstract 1
- 239000002841 Lewis acid Substances 0.000 abstract 1
- WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical compound [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 abstract 1
- 229910052782 aluminium Inorganic materials 0.000 abstract 1
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000007859 condensation product Substances 0.000 abstract 1
- 150000008282 halocarbons Chemical class 0.000 abstract 1
- 150000007517 lewis acids Chemical class 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 239000000047 product Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 229940014800 succinic anhydride Drugs 0.000 abstract 1
- 235000005074 zinc chloride Nutrition 0.000 abstract 1
- 239000011592 zinc chloride Substances 0.000 abstract 1
Landscapes
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT48596/85A IT1200123B (it) | 1985-09-27 | 1985-09-27 | Procedimento per la preparazione di alfa-(p-terbutilfenil)-4-(idrossidifenilmetil)-1-piperidinobutanolo |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES548555A0 ES548555A0 (es) | 1986-11-16 |
| ES8700849A1 true ES8700849A1 (es) | 1986-11-16 |
Family
ID=11267539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES548555A Expired ES8700849A1 (es) | 1985-09-27 | 1985-11-05 | Un procedimiento para la preparacion de -(p-t-butilfenil)-4-(hidroxidifenilmetil)-1-piperidinobutanol |
Country Status (5)
| Country | Link |
|---|---|
| AT (1) | AT392782B (it) |
| ES (1) | ES8700849A1 (it) |
| IT (1) | IT1200123B (it) |
| SU (1) | SU1486058A3 (it) |
| YU (1) | YU44293B (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2681861B1 (fr) * | 1991-10-01 | 1995-06-09 | Isochem Sa | Procede de preparation d'une forme polymorphique de la terfenadine, a point de fusion eleve, d'une plus grande purete et produit obtenu. |
| EP1026147B1 (en) | 1993-06-24 | 2003-11-19 | Albany Molecular Research, Inc. | Compounds useful as intermediates in the production of piperidine derivatives |
| US20020007068A1 (en) | 1999-07-16 | 2002-01-17 | D'ambra Thomas E. | Piperidine derivatives and process for their production |
| US6743941B2 (en) | 2001-06-15 | 2004-06-01 | Aventis Pharma Deutschland Gmbh | Process for the production of piperidine derivatives |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA728544B (en) * | 1972-01-28 | 1974-02-27 | Richardson Merrell Inc | Alpha-aryl-4-substituted piperidinoalkanol derivatives |
-
1985
- 1985-09-27 IT IT48596/85A patent/IT1200123B/it active
- 1985-11-05 ES ES548555A patent/ES8700849A1/es not_active Expired
-
1986
- 1986-07-02 YU YU116886A patent/YU44293B/xx unknown
- 1986-09-26 AT AT257686A patent/AT392782B/de not_active IP Right Cessation
- 1986-09-26 SU SU864028203A patent/SU1486058A3/ru active
Also Published As
| Publication number | Publication date |
|---|---|
| IT8548596A0 (it) | 1985-09-27 |
| YU44293B (en) | 1990-04-30 |
| ES548555A0 (es) | 1986-11-16 |
| SU1486058A3 (ru) | 1989-06-07 |
| YU116886A (en) | 1987-12-31 |
| AT392782B (de) | 1991-06-10 |
| ATA257686A (de) | 1990-11-15 |
| IT1200123B (it) | 1989-01-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19971001 |