ES8708183A1 - Un procedimiento para la preparacion de una composicion liofilizada de lipidos. - Google Patents

Un procedimiento para la preparacion de una composicion liofilizada de lipidos.

Info

Publication number
ES8708183A1
ES8708183A1 ES556057A ES556057A ES8708183A1 ES 8708183 A1 ES8708183 A1 ES 8708183A1 ES 556057 A ES556057 A ES 556057A ES 556057 A ES556057 A ES 556057A ES 8708183 A1 ES8708183 A1 ES 8708183A1
Authority
ES
Spain
Prior art keywords
compositions
water
emulsion compositions
parenteral
lyophilized emulsion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES556057A
Other languages
English (en)
Other versions
ES556057A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of ES556057A0 publication Critical patent/ES556057A0/es
Publication of ES8708183A1 publication Critical patent/ES8708183A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

METODO DE OBTENER UNA COMPOSICION LIOFILIZADA DE LIPIDOS. CONSISTE EN PREPARAR UNA EMULSION EN FORMA LIQUIDA DISPERSANDO EN AGUA EL LIPIDO Y EL EMULGENTE; AGREGAR A LA EMULSION EL HIDRATO DE CARBONO; ROCIAR LA EMULSION OBTENIDA EN FORMA DE FINAS GOTITAS CON UN BAÑO FLUIDO A EBULLICION QUE TIENE UN PUNTO DE EBULLICION INFERIOR A -20GC, RECOGER LAS GOTITAS CONGELADAS CON UNA PALETA TAMIZADORA Y TRANSFERIRLAS, MANTENIENDOLAS CONGELADAS, A UN LIFILIZADOR PREENFRIADO, MANTENIENDO LAS SIGUIENTES CONDICIONES DE LIOFILIZACION: TIEMPO 0 A -30GC; 24 HORAS A -20GC; 48 HORAS A -5GC; 60 HORAS A 15GC; Y 72 HORAS FUERA, CON LO QUE SE OBTIENE LA COMPOSICION LIOFILIZADA EN CONDICIONES DE SER ENVASADA. TIENE UTILIDAD PARA PREPARAR COMPOSICIONES DE NUTRICION PARENTERAL. B
ES556057A 1985-07-29 1986-06-13 Un procedimiento para la preparacion de una composicion liofilizada de lipidos. Expired ES8708183A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75979785A 1985-07-29 1985-07-29

Publications (2)

Publication Number Publication Date
ES556057A0 ES556057A0 (es) 1987-10-01
ES8708183A1 true ES8708183A1 (es) 1987-10-01

Family

ID=25056993

Family Applications (1)

Application Number Title Priority Date Filing Date
ES556057A Expired ES8708183A1 (es) 1985-07-29 1986-06-13 Un procedimiento para la preparacion de una composicion liofilizada de lipidos.

Country Status (11)

Country Link
EP (1) EP0211257A3 (es)
JP (1) JPS6229513A (es)
KR (1) KR870000922A (es)
AU (1) AU6021586A (es)
CA (1) CA1273574A (es)
DK (1) DK359686A (es)
ES (1) ES8708183A1 (es)
GR (1) GR861460B (es)
IL (1) IL78930A0 (es)
NZ (1) NZ216355A (es)
ZA (1) ZA864032B (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78929A0 (en) * 1985-07-29 1986-09-30 Abbott Lab Microemulsion compositions for parenteral administration
US5461037A (en) * 1985-10-15 1995-10-24 Clintec Nutrition Company Lipid emulsion
NZ223660A (en) * 1987-03-05 1990-11-27 Liposome Co Inc Low toxicity drug-lipid complexes; methods of making them; and method of determining their toxicity
WO1988008301A1 (en) * 1987-04-22 1988-11-03 Baxter Travenol Laboratories, Inc. Lipid emulsion and method for intravenous infusion
GB8715238D0 (en) * 1987-06-29 1987-08-05 Quadrant Bioresources Ltd Food process
JP2643217B2 (ja) * 1988-01-22 1997-08-20 エーザイ株式会社 脂溶性物質水性液
DE68903930T2 (de) * 1988-11-23 1993-05-19 Abbott Lab Lipidemulsion zur behandlung von aids.
JPH07121858B2 (ja) * 1988-12-20 1995-12-25 メディコントロール コーポレーション 熱で脱水したエマルジョン組成物
US5044091B1 (en) * 1989-04-18 1997-12-30 Sankyo Co Method of preparing a freeze-dried formulation of a drug
AU665931B2 (en) * 1990-11-06 1996-01-25 Nippon Shinyaku Co. Ltd. Lyophilized preparation and production thereof
WO1992007551A1 (en) * 1990-11-06 1992-05-14 Nippon Shinyaku Co., Ltd. Process for producing fat emulsion
WO1992015283A1 (en) * 1991-03-01 1992-09-17 Novo Nordisk A/S Parenteral emulsion
WO1992017162A1 (en) * 1991-04-05 1992-10-15 Warner-Lambert Company Lyophilized emulsion
IL101007A (en) * 1992-02-18 1997-08-14 Pharmos Ltd Dry stable compositions prepared by lyophilization
EP0626850B1 (en) * 1992-02-18 2002-05-15 Pharmos Corporation Dry compositions for preparing submicron emulsions
DE4244122C1 (de) * 1992-12-24 1994-06-01 Sanol Arznei Schwarz Gmbh Lyophilisierte, wirkstoffhaltige Emulsion zur intravenösen Applikation
DE4309579C3 (de) * 1993-03-24 2000-01-27 Sanol Arznei Schwarz Gmbh Pharmazeutische Zusammensetzung in Form einer Packung
FR2768341B1 (fr) * 1997-09-18 2000-04-14 Lab Francais Du Fractionnement Composition pharmaceutique placebo lyophilisable destinee a imiter un medicament, notamment a base de proteines ou de polypeptides
JP2004323444A (ja) * 2003-04-25 2004-11-18 Hamamatsu Kagaku Gijutsu Kenkyu Shinkokai 凍結乾燥微粒子製剤およびその製法
RU2308940C1 (ru) * 2006-05-16 2007-10-27 Государственное образовательное учреждение высшего профессионального образования Восточно-Сибирский государственный технологический университет Способ получения липосом, обладающих иммунокорригирующим и гепатопротекторным действием
AR063704A1 (es) 2006-09-14 2009-02-11 Makhteshim Chem Works Ltd Nanoparticulas de pesticida obtenida obtenidas a partir de microemulsiones y nanoemulsiones
WO2008033024A2 (en) 2006-09-15 2008-03-20 Echo Pharmaceuticals B.V. Dosage unit for sublingual, buccal or oral administration of water-insoluble pharmaceutically active substances
PL2061427T3 (pl) * 2006-09-15 2011-12-30 Echo Pharmaceuticals Bv Granulat zawierający substancję farmaceutycznie aktywną i emulgator oraz sposób jego wytwarzania
MX344559B (es) 2008-04-29 2016-12-20 Ascendis Pharma As Compuestos de hormona de crecimiento humana recombinante unidos al peg.
RU2417075C1 (ru) * 2009-11-30 2011-04-27 Государственное образовательное учреждение высшего профессионального образования "Восточно-Сибирский государственный технологический университет" Способ получения липосомального средства, обладающего ранозаживляющим действием
MX337432B (es) 2009-12-15 2016-03-04 Ascendis Pharma As Composicion de la hormona del crecimiento seca enlazada transitoriamente a un portador del polimero.
JP6458322B2 (ja) * 2013-05-06 2019-01-30 ディーエスエム アイピー アセッツ ビー．ブイ．Ｄｓｍ Ｉｐ Ａｓｓｅｔｓ Ｂ．Ｖ． 粉末状ビタミンｅ製剤
SG11201703870UA (en) 2014-11-18 2017-06-29 Ascendis Pharma Endocrinology Div As Novel polymeric hgh prodrugs
PT3220892T (pt) 2014-11-21 2021-11-05 Ascendis Pharma Endocrinology Div A/S Formas de dosagem de hormona do crescimento de longa ação
AU2020233198B2 (en) 2019-03-04 2025-05-15 Ascendis Pharma Endocrinology Division A/S Long-acting growth hormone dosage forms with superior efficacy to daily somatropin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1047924A (en) * 1973-10-30 1979-02-06 Kyowa Hakko Kogyo Co. Powdered emulsion product and method of production
DE2928039A1 (de) * 1979-07-11 1981-02-05 Meyer Castens Chem Fab Co Verfahren zur herstellung von trockenemulsionen und deren verwendung
FR2561916B1 (fr) * 1984-03-30 1987-12-11 Lafon Labor Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau

Also Published As

Publication number Publication date
DK359686A (da) 1987-01-30
IL78930A0 (en) 1986-09-30
AU6021586A (en) 1987-02-05
EP0211257A2 (en) 1987-02-25
GR861460B (en) 1986-10-07
ZA864032B (en) 1987-01-28
NZ216355A (en) 1989-04-26
ES556057A0 (es) 1987-10-01
CA1273574A (en) 1990-09-04
KR870000922A (ko) 1987-03-10
JPS6229513A (ja) 1987-02-07
DK359686D0 (da) 1986-07-29
EP0211257A3 (en) 1987-11-19

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603