ES8800948A1 - Procedimiento para preparar espiro-dioxolanos-ditiolanos y oxotiolanos - Google Patents

Procedimiento para preparar espiro-dioxolanos-ditiolanos y oxotiolanos

Info

Publication number
ES8800948A1
ES8800948A1 ES550896A ES550896A ES8800948A1 ES 8800948 A1 ES8800948 A1 ES 8800948A1 ES 550896 A ES550896 A ES 550896A ES 550896 A ES550896 A ES 550896A ES 8800948 A1 ES8800948 A1 ES 8800948A1
Authority
ES
Spain
Prior art keywords
dioxolanes
oxotiolanes
ditiolanes
procedure
preparing spiro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES550896A
Other languages
English (en)
Other versions
ES550896A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19853501225 external-priority patent/DE3501225A1/de
Priority claimed from DE19853504284 external-priority patent/DE3504284A1/de
Priority claimed from DE19853504281 external-priority patent/DE3504281A1/de
Priority claimed from DE19853504286 external-priority patent/DE3504286A1/de
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES8800948A1 publication Critical patent/ES8800948A1/es
Publication of ES550896A0 publication Critical patent/ES550896A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D497/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D497/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having oxygen and sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D497/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

METODO DE PREPARAR ESPIRO-DIOXOLANOS, -DITIOLANOS Y OXOTIOLANOS. CONSISTE EN CICLIZAR UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III), PARA OBTENER LOS COMPUESTOS DESEADOS DE FORMULA (I), DONDE R1 ES H, UN GRUPO ALQUILO CON C 1 A 6 Y OTROS; R2 Y R3 SON INDEPENDIENTEMENTE UNA DE OTRA, UN GRUPO ALQUILO DE C 1 A 6 Y OTROS; X1 Y X2 REPRESENTAN, INDEPENDEIENTEMENTE UNA DE OTRA, OXIGENO O AZUFRE; Y M Y N, INDEPENDIENTEMENTE UNA DE OTRA, REPRESENTAN 1, 2, 3 O 4, CON LA CONDICION DE QUE M MAS N NO SEA SUPERIOR A 6. TIENEN APLICACION PARA TRATAMIENTOS TERAPEUTICOS.
ES550896A 1985-01-16 1986-01-15 Procedimiento para preparar espiro-dioxolanos-ditiolanos y oxotiolanos Expired ES8800948A1 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19853501225 DE3501225A1 (de) 1985-01-16 1985-01-16 Spirodioxolane, ihre herstellung und verwendung
DE19853504284 DE3504284A1 (de) 1985-02-08 1985-02-08 Spiro-dithiolane, ihre herstellung und verwendung
DE19853504281 DE3504281A1 (de) 1985-02-08 1985-02-08 Spiro-oxothiolane, ihre herstellung und verwendung
DE19853504286 DE3504286A1 (de) 1985-02-08 1985-02-08 Spiro-oxothiolane, ihre herstellung und verwendung

Publications (2)

Publication Number Publication Date
ES8800948A1 true ES8800948A1 (es) 1987-12-01
ES550896A0 ES550896A0 (es) 1987-12-01

Family

ID=27433274

Family Applications (1)

Application Number Title Priority Date Filing Date
ES550896A Expired ES8800948A1 (es) 1985-01-16 1986-01-15 Procedimiento para preparar espiro-dioxolanos-ditiolanos y oxotiolanos

Country Status (10)

Country Link
US (1) US4735944A (es)
EP (1) EP0189370A3 (es)
AU (1) AU586848B2 (es)
DK (1) DK17286A (es)
ES (1) ES8800948A1 (es)
FI (1) FI860186A7 (es)
GR (1) GR860078B (es)
HU (1) HU196073B (es)
NZ (1) NZ214821A (es)
PT (1) PT81835B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3853758T2 (de) * 1987-10-05 1995-09-07 Yamanouchi Pharma Co Ltd Heterozyklische Spiroverbindungen und ihre Herstellung.
US4900830A (en) * 1987-10-28 1990-02-13 Israel Institute For Biological Research Process for labelling sulfur-containing compounds
US5173484A (en) * 1988-02-05 1992-12-22 Bayer Aktiengesellschaft Quinolone- and naphthyridone carboxylic acid derivatives, process for their production, antibacterial compositions and feed additives containing them
GB8816299D0 (en) * 1988-07-08 1988-08-10 Merck Sharp & Dohme Therapeutic agents
US5075317A (en) * 1989-06-21 1991-12-24 Fisons Corporation Spirofurane derivatives
US5594000A (en) * 1989-06-21 1997-01-14 Astra Ab Spirofurane derivatives
HU204530B (en) * 1989-08-10 1992-01-28 Richter Gedeon Vegyeszet Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
US5534520A (en) * 1990-04-10 1996-07-09 Fisher; Abraham Spiro compounds containing five-membered rings
US5407938A (en) * 1990-04-10 1995-04-18 Israel Institute For Biological Research Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines)
US5852029A (en) * 1990-04-10 1998-12-22 Israel Institute For Biological Research Aza spiro compounds acting on the cholinergic system with muscarinic agonist activity
US5073560A (en) * 1990-07-20 1991-12-17 Fisons Corporation Spiro-isoxazolidine derivatives as cholinergic agents
CN1105723C (zh) * 1996-08-28 2003-04-16 普罗克特和甘保尔公司 螺环金属蛋白酶抑制剂
SE9701396D0 (sv) * 1997-04-15 1997-04-15 Astra Pharma Prod Compounds
JP2003506468A (ja) * 1999-08-13 2003-02-18 アベンティス・クロップサイエンス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 農薬としての複素環式スピロ化合物
US9034891B2 (en) 2009-01-26 2015-05-19 Israel Institute For Biological Research Bicyclic heterocyclic spiro compounds
AU2010207486B2 (en) 2009-01-26 2013-03-07 Israel Institute For Biological Research Bicyclic heterocyclic spiro compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL48452A (en) * 1975-11-11 1979-07-25 Purdue Frederick Co Spiro (1,3-dioxolane-4,3') quinuclidines,their preparationand pharmaceutical compositions comprising them

Also Published As

Publication number Publication date
EP0189370A2 (de) 1986-07-30
DK17286A (da) 1986-07-17
AU586848B2 (en) 1989-07-27
HU196073B (en) 1988-09-28
DK17286D0 (da) 1986-01-14
PT81835A (en) 1986-02-01
EP0189370A3 (de) 1988-01-27
AU5224286A (en) 1986-07-24
GR860078B (en) 1986-04-30
HUT42774A (en) 1987-08-28
ES550896A0 (es) 1987-12-01
NZ214821A (en) 1989-03-29
US4735944A (en) 1988-04-05
FI860186L (fi) 1986-07-17
FI860186A7 (fi) 1986-07-17
PT81835B (en) 1987-11-19
FI860186A0 (fi) 1986-01-15

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