ES8801202A1 - Un procedimiento para preparar derivados de alcanoles aroma-ticos heteropoliciclicos - Google Patents
Un procedimiento para preparar derivados de alcanoles aroma-ticos heteropoliciclicosInfo
- Publication number
- ES8801202A1 ES8801202A1 ES548868A ES548868A ES8801202A1 ES 8801202 A1 ES8801202 A1 ES 8801202A1 ES 548868 A ES548868 A ES 548868A ES 548868 A ES548868 A ES 548868A ES 8801202 A1 ES8801202 A1 ES 8801202A1
- Authority
- ES
- Spain
- Prior art keywords
- rings
- alkyl
- carbon atoms
- different
- same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000009472 formulation Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 125000003367 polycyclic group Chemical group 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000003118 aryl group Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000005842 heteroatom Chemical group 0.000 abstract 3
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000002837 carbocyclic group Chemical group 0.000 abstract 2
- 125000004122 cyclic group Chemical group 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000001424 substituent group Chemical group 0.000 abstract 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical class CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- -1 alkoxy halogen Chemical class 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002170 ethers Chemical class 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- CBOIHMRHGLHBPB-UHFFFAOYSA-N hydroxymethyl Chemical compound O[CH2] CBOIHMRHGLHBPB-UHFFFAOYSA-N 0.000 abstract 1
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Natural products C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/91—Dibenzofurans; Hydrogenated dibenzofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/02—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/18—Ring systems of four or more rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/74—Naphthothiophenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/76—Dibenzothiophenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Steroid Compounds (AREA)
Abstract
PROCEDIMIOENTO PARA PREPARAR DERIVADOS DE ALCANOLES AROMATICOS HETEROPOLICICLICOS. CONSISTE EN REDUCIR UN COMPUESTO DE FORMULA (II) CON UN HIDRURO DE LITIO ALUMINIO, EN MEZCLAS DE ETER, ALCOHOL Y HALOGENO-ALCANO Y A UNA TEMPERATURA INFERIOR A 80JC, PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO: R, UN SISTEMA DE ANILLOS CONDENSADOS DE 3 A 5 ANILLOS OPCIONALMENTE SUSTITUIDOS CON DOS SUSTITUYENTES ELEGIDOS ENTRE HAL, CIANO Y ALQUILO DE C 1 A 4, R'' UN RADICAL DE FORMULA (III); R5 Y R6 IGUALES O DIFERENTES, ALQUILO DE C 1 A 3; R7 Y R8, H O ALQUILO DE C 1 A 3; Y M, 0 O 1. SE UTILIZAN COMO AGENTES BIOCIDAS Y ANTITUMORALES.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848428930A GB8428930D0 (en) | 1984-11-15 | 1984-11-15 | Polycyclic biocidal compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES548868A0 ES548868A0 (es) | 1987-12-16 |
| ES8801202A1 true ES8801202A1 (es) | 1987-12-16 |
Family
ID=10569799
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES548868A Expired ES8801202A1 (es) | 1984-11-15 | 1985-11-14 | Un procedimiento para preparar derivados de alcanoles aroma-ticos heteropoliciclicos |
| ES557177A Expired ES8802024A1 (es) | 1984-11-15 | 1986-11-03 | Un procedimiento para preparar derivados de alcanoles aromaticos heteropoliciclicos. |
| ES557176A Expired ES8801630A1 (es) | 1984-11-15 | 1986-11-03 | Un procedimiento para preparar derivados de alcanoles aromaticos heteropoliciclicos. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES557177A Expired ES8802024A1 (es) | 1984-11-15 | 1986-11-03 | Un procedimiento para preparar derivados de alcanoles aromaticos heteropoliciclicos. |
| ES557176A Expired ES8801630A1 (es) | 1984-11-15 | 1986-11-03 | Un procedimiento para preparar derivados de alcanoles aromaticos heteropoliciclicos. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0183439B1 (es) |
| JP (1) | JPH0745475B2 (es) |
| KR (1) | KR920001777B1 (es) |
| AT (1) | ATE85333T1 (es) |
| DE (1) | DE3587066T2 (es) |
| DK (1) | DK526785A (es) |
| ES (3) | ES8801202A1 (es) |
| GB (1) | GB8428930D0 (es) |
| GR (1) | GR852762B (es) |
| HU (1) | HU199818B (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6174913B1 (en) | 1998-06-05 | 2001-01-16 | The University Of North Carolina At Chapel Hill | Naphtho- and dihydrobenzo-thiophene derivatives as cytotoxic antitumor agents |
| US9312501B2 (en) | 2012-09-28 | 2016-04-12 | Polyera Corporation | Semiconducting compounds and optoelectronic devices incorporating same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4022805A (en) * | 1974-03-07 | 1977-05-10 | Hoffmann-La Roche Inc. | 8-Halo-dibenzofuran-3-acetic acids and certain esters thereof |
| JPS5283455A (en) * | 1976-01-01 | 1977-07-12 | Hoffmann La Roche | Benzofuran derivatives |
| CH628045A5 (en) * | 1976-03-24 | 1982-02-15 | Hoffmann La Roche | Process for the preparation of dibenzothiophene derivatives |
| US4219657A (en) * | 1977-12-19 | 1980-08-26 | Hoffmann-La Roche Inc. | Dibenzothiophenes |
| GB8313571D0 (en) * | 1983-05-17 | 1983-06-22 | Wellcome Found | Chemical compounds |
-
1984
- 1984-11-15 GB GB848428930A patent/GB8428930D0/en active Pending
-
1985
- 1985-11-14 DK DK526785A patent/DK526785A/da not_active Application Discontinuation
- 1985-11-14 AT AT85308279T patent/ATE85333T1/de not_active IP Right Cessation
- 1985-11-14 DE DE8585308279T patent/DE3587066T2/de not_active Expired - Fee Related
- 1985-11-14 KR KR8508500A patent/KR920001777B1/ko not_active Expired
- 1985-11-14 JP JP60255827A patent/JPH0745475B2/ja not_active Expired - Lifetime
- 1985-11-14 GR GR852762A patent/GR852762B/el unknown
- 1985-11-14 HU HU854341A patent/HU199818B/hu not_active IP Right Cessation
- 1985-11-14 ES ES548868A patent/ES8801202A1/es not_active Expired
- 1985-11-14 EP EP85308279A patent/EP0183439B1/en not_active Expired - Lifetime
-
1986
- 1986-11-03 ES ES557177A patent/ES8802024A1/es not_active Expired
- 1986-11-03 ES ES557176A patent/ES8801630A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| HU199818B (en) | 1990-03-28 |
| ES548868A0 (es) | 1987-12-16 |
| ES8801630A1 (es) | 1988-02-16 |
| DK526785A (da) | 1986-05-16 |
| KR860004046A (ko) | 1986-06-16 |
| ATE85333T1 (de) | 1993-02-15 |
| KR920001777B1 (en) | 1992-03-02 |
| DE3587066T2 (de) | 1993-08-12 |
| EP0183439A2 (en) | 1986-06-04 |
| ES557177A0 (es) | 1988-03-16 |
| HUT40094A (en) | 1986-11-28 |
| EP0183439B1 (en) | 1993-02-03 |
| ES557176A0 (es) | 1988-02-16 |
| GB8428930D0 (en) | 1984-12-27 |
| JPH0745475B2 (ja) | 1995-05-17 |
| ES8802024A1 (es) | 1988-03-16 |
| JPS61122274A (ja) | 1986-06-10 |
| DK526785D0 (da) | 1985-11-14 |
| EP0183439A3 (en) | 1988-08-10 |
| GR852762B (es) | 1986-03-13 |
| DE3587066D1 (de) | 1993-03-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19971001 |