ES8801263A1 - Procedimiento para la preparacion de derivados de 10 l-metoxi-6-metilergolina y sus sales de adicion de acidos - Google Patents

Procedimiento para la preparacion de derivados de 10 l-metoxi-6-metilergolina y sus sales de adicion de acidos

Info

Publication number: ES8801263A1
Authority: ES; Spain
Prior art keywords: methylergoline; metoxi; derivatives; procedure; preparation
Prior art date: 1985-06-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

ES556358A

Other languages

English (en)

Spanish (es)

Other versions

ES556358A0 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Richter Gedeon Vegyeszeti Gyar Nyrt

Original Assignee

Richter Gedeon Vegyeszeti Gyar RT

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-06-21

Filing date

1986-06-20

Publication date

1988-01-01

1986-06-20 Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT

1988-01-01 Publication of ES556358A0 publication Critical patent/ES556358A0/es

1988-01-01 Publication of ES8801263A1 publication Critical patent/ES8801263A1/es

Status Expired legal-status Critical Current

Links

239000002253 acid Substances 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
150000007513 acids Chemical class 0.000 title 1
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 abstract 2
GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Chemical group BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical group ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
YSEXMKHXIOCEJA-FVFQAYNVSA-N Nicergoline Chemical compound C([C@@H]1C[C@]2([C@H](N(C)C1)CC=1C3=C2C=CC=C3N(C)C=1)OC)OC(=O)C1=CN=CC(Br)=C1 YSEXMKHXIOCEJA-FVFQAYNVSA-N 0.000 abstract 1
229910052794 bromium Inorganic materials 0.000 abstract 1
229910052801 chlorine Inorganic materials 0.000 abstract 1
239000000460 chlorine Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical group II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
229960003642 nicergoline Drugs 0.000 abstract 1
239000000810 peripheral vasodilating agent Substances 0.000 abstract 1
229960002116 peripheral vasodilator Drugs 0.000 abstract 1
230000005855 radiation Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ES556358A 1985-06-21 1986-06-20 Procedimiento para la preparacion de derivados de 10 l-metoxi-6-metilergolina y sus sales de adicion de acidos Expired ES8801263A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU852446A HU193781B (en)	1985-06-21	1985-06-21	Process for producing 10alpha-methoxy-6-methylergoline derivatives and acid additional salts thereof

Publications (2)

Publication Number	Publication Date
ES556358A0 ES556358A0 (es)	1988-01-01
ES8801263A1 true ES8801263A1 (es)	1988-01-01

Family

ID=10959396

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES556358A Expired ES8801263A1 (es)	1985-06-21	1986-06-20	Procedimiento para la preparacion de derivados de 10 l-metoxi-6-metilergolina y sus sales de adicion de acidos

Country Status (14)

Country	Link
BE (1)	BE904956A (cs)
CS (1)	CS255876B2 (cs)
DD (1)	DD246110A5 (cs)
DE (1)	DE3620487A1 (cs)
DK (1)	DK291986A (cs)
ES (1)	ES8801263A1 (cs)
FR (1)	FR2583755B1 (cs)
GB (1)	GB2177090B (cs)
GR (1)	GR861619B (cs)
HU (1)	HU193781B (cs)
IT (1)	IT1190135B (cs)
LU (1)	LU86486A1 (cs)
NL (1)	NL8601584A (cs)
PT (1)	PT82807B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU196598B (en) *	1986-04-25	1988-12-28	Richter Gedeon Vegyeszet	Process for producing 1- and/or 8-substituted 2-halogenated ergoline derivatives and pharmaceutics comprising such compounds
GB9603226D0 (en) *	1996-02-15	1996-04-17	Pharmacia Spa	Heterocyclyl-ergoline derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1094965B (it) *	1978-04-05	1985-08-10	Corvi Mora E	Procedimento di preparazione di derivati del lisergolo
HU193782B (en) *	1985-06-21	1987-11-30	Richter Gedeon Vegyeszet	Process for producing 2-halogeno-nicergoline derivatives and acid additional salts thereof

1985
- 1985-06-21 HU HU852446A patent/HU193781B/hu not_active IP Right Cessation
1986
- 1986-06-19 BE BE0/216805A patent/BE904956A/fr not_active IP Right Cessation
- 1986-06-19 DE DE19863620487 patent/DE3620487A1/de not_active Withdrawn
- 1986-06-19 NL NL8601584A patent/NL8601584A/nl not_active Application Discontinuation
- 1986-06-19 FR FR868608869A patent/FR2583755B1/fr not_active Expired - Lifetime
- 1986-06-19 IT IT20854/86A patent/IT1190135B/it active
- 1986-06-20 DK DK291986A patent/DK291986A/da not_active Application Discontinuation
- 1986-06-20 CS CS864585A patent/CS255876B2/cs unknown
- 1986-06-20 ES ES556358A patent/ES8801263A1/es not_active Expired
- 1986-06-20 GR GR861619A patent/GR861619B/el unknown
- 1986-06-20 PT PT82807A patent/PT82807B/pt not_active IP Right Cessation
- 1986-06-20 GB GB8615121A patent/GB2177090B/en not_active Expired
- 1986-06-20 LU LU86486A patent/LU86486A1/de unknown
- 1986-06-20 DD DD86291508A patent/DD246110A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
GB2177090B (en)	1989-07-12
NL8601584A (nl)	1987-01-16
FR2583755B1 (fr)	1990-06-22
GR861619B (en)	1986-10-21
HU193781B (en)	1987-11-30
IT8620854A1 (it)	1987-12-19
GB2177090A (en)	1987-01-14
DE3620487A1 (de)	1987-01-02
FR2583755A1 (fr)	1986-12-26
ES556358A0 (es)	1988-01-01
BE904956A (fr)	1986-12-19
PT82807A (en)	1986-07-01
IT8620854A0 (it)	1986-06-19
DK291986D0 (da)	1986-06-20
DD246110A5 (de)	1987-05-27
HUT41023A (en)	1987-03-30
DK291986A (da)	1986-12-22
CS255876B2 (en)	1988-03-15
PT82807B (pt)	1988-04-21
IT1190135B (it)	1988-02-10
GB8615121D0 (en)	1986-07-23
LU86486A1 (de)	1986-12-02

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Legal Events

Date	Code	Title	Description
1997-04-16	FD1A	Patent lapsed	Effective date: 19970303