ES8801292A1 - Procedimiento para la obtencion de compuestos de heterociclil-penem - Google Patents
Procedimiento para la obtencion de compuestos de heterociclil-penemInfo
- Publication number
- ES8801292A1 ES8801292A1 ES553986A ES553986A ES8801292A1 ES 8801292 A1 ES8801292 A1 ES 8801292A1 ES 553986 A ES553986 A ES 553986A ES 553986 A ES553986 A ES 553986A ES 8801292 A1 ES8801292 A1 ES 8801292A1
- Authority
- ES
- Spain
- Prior art keywords
- ring
- compounds
- penem
- formula
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 Heterocyclic penem compounds Chemical class 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
Abstract
PROCEDIMIENTO PARA OBTENER COMPUESTOS DE HETEROCICLIL-PENEM. COMPRENDE: A) DISOLVER A UN COMPUESTO DE FORMULA (II) EN DIOXANO; Y B( CALENTAR LA DISOLUCION ENTRE 30J Y 160JC, PARA CERRAR EL ANILLO DE (II) Y OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: R1, ALQUILO INFERIOR SUSTITUIDO POR HIDROXI; R2, UN RESTO HETEROARILO DE 5 MIEMBROS MONOCICLICO; R3, CARBOXILO; XB, FOSFONIO TRES VECES SUSTITUIDO; R''3, R3; Y Z, O O S. SE UTILIZAN PARA COMBATIR INFECCIONES PRODUCIDAS POR BACTERIAS GRAM-(B) Y GRAM-(C).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH163585 | 1985-04-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES553986A0 ES553986A0 (es) | 1987-12-16 |
| ES8801292A1 true ES8801292A1 (es) | 1987-12-16 |
Family
ID=4215062
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES553986A Expired ES8801292A1 (es) | 1985-04-17 | 1986-04-15 | Procedimiento para la obtencion de compuestos de heterociclil-penem |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0199675A1 (es) |
| JP (1) | JPS61243088A (es) |
| KR (1) | KR860008186A (es) |
| AU (1) | AU5618986A (es) |
| DK (1) | DK172486A (es) |
| ES (1) | ES8801292A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4826832A (en) * | 1986-05-06 | 1989-05-02 | Ciba-Geigy Corporation | Penen compounds |
| CA2019260C (en) * | 1989-06-22 | 1999-06-29 | Hirokazu Ochiai | Penam derivatives and salts thereof, processes for producing the same and antibacterial agent comprising the same |
| JP2973126B2 (ja) * | 1989-06-22 | 1999-11-08 | 富山化学工業株式会社 | 新規なペナム誘導体およびその塩 |
| EP0597401A3 (en) * | 1992-11-11 | 1995-07-26 | Takeda Chemical Industries Ltd | Preparation of penemes. |
| KR0168979B1 (ko) * | 1995-07-12 | 1999-01-15 | 김종인 | 티아졸릴 트리아졸로티아졸 유도체 |
| CN113943263B (zh) * | 2021-11-17 | 2025-03-21 | 凯美克(上海)医药科技有限公司 | 一种2-(氨基甲基)-1,3-噻唑-5-羧酸甲酯的合成方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4168314A (en) * | 1977-11-17 | 1979-09-18 | Merck & Co., Inc. | 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid |
| EP0003960B1 (de) * | 1978-02-02 | 1983-06-29 | Ciba-Geigy Ag | 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate |
| EP0109362A1 (de) * | 1982-11-16 | 1984-05-23 | Ciba-Geigy Ag | Heterocyclylverbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren |
-
1986
- 1986-04-11 EP EP86810170A patent/EP0199675A1/de not_active Withdrawn
- 1986-04-15 ES ES553986A patent/ES8801292A1/es not_active Expired
- 1986-04-16 DK DK172486A patent/DK172486A/da active IP Right Grant
- 1986-04-16 AU AU56189/86A patent/AU5618986A/en not_active Abandoned
- 1986-04-17 JP JP61087223A patent/JPS61243088A/ja active Pending
- 1986-04-17 KR KR1019860002953A patent/KR860008186A/ko not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| DK172486A (da) | 1986-10-18 |
| JPS61243088A (ja) | 1986-10-29 |
| EP0199675A1 (de) | 1986-10-29 |
| ES553986A0 (es) | 1987-12-16 |
| KR860008186A (ko) | 1986-11-12 |
| DK172486D0 (da) | 1986-04-16 |
| AU5618986A (en) | 1986-10-23 |
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