FI109204B - Immuunimäärityksiä ja monoklonaalisia vasta-aineita protrombiiniaktivaatiopeptideille ja niiden hajoamistuotteille - Google Patents

Immuunimäärityksiä ja monoklonaalisia vasta-aineita protrombiiniaktivaatiopeptideille ja niiden hajoamistuotteille Download PDF

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Publication number
FI109204B
FI109204B FI922017A FI922017A FI109204B FI 109204 B FI109204 B FI 109204B FI 922017 A FI922017 A FI 922017A FI 922017 A FI922017 A FI 922017A FI 109204 B FI109204 B FI 109204B
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FI
Finland
Prior art keywords
prothrombin
antibody
labeled
monoclonal antibody
sample
Prior art date
Application number
FI922017A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI922017L (fi
FI922017A0 (fi
Inventor
Bryan Timothy Butman
Jerald Paul Steiner
Bryant Mckoy Moore
Frederick Anthony Dombrose
Marcie Jones Hursting
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23714193&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI109204(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI922017L publication Critical patent/FI922017L/fi
Publication of FI922017A0 publication Critical patent/FI922017A0/fi
Application granted granted Critical
Publication of FI109204B publication Critical patent/FI109204B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/974—Thrombin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Transceivers (AREA)
  • Mobile Radio Communication Systems (AREA)
  • Exhaust Gas After Treatment (AREA)
FI922017A 1989-11-06 1992-05-05 Immuunimäärityksiä ja monoklonaalisia vasta-aineita protrombiiniaktivaatiopeptideille ja niiden hajoamistuotteille FI109204B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US43196489A 1989-11-06 1989-11-06
US43196489 1989-11-06
PCT/US1990/006501 WO1991006861A1 (en) 1989-11-06 1990-11-02 Immunoassays for and monoclonal antibodies to prothrombin activation peptides and their degradation products
US9006501 1990-11-02

Publications (3)

Publication Number Publication Date
FI922017L FI922017L (fi) 1992-05-05
FI922017A0 FI922017A0 (fi) 1992-05-05
FI109204B true FI109204B (fi) 2002-06-14

Family

ID=23714193

Family Applications (1)

Application Number Title Priority Date Filing Date
FI922017A FI109204B (fi) 1989-11-06 1992-05-05 Immuunimäärityksiä ja monoklonaalisia vasta-aineita protrombiiniaktivaatiopeptideille ja niiden hajoamistuotteille

Country Status (15)

Country Link
US (1) US5830681A (da)
EP (1) EP0594576B1 (da)
JP (1) JP2918688B2 (da)
KR (1) KR100202773B1 (da)
AT (1) ATE182366T1 (da)
AU (1) AU655918B2 (da)
CA (1) CA2071211C (da)
DE (1) DE69033220T2 (da)
DK (1) DK0594576T3 (da)
ES (1) ES2136598T3 (da)
FI (1) FI109204B (da)
GR (1) GR3031607T3 (da)
IE (1) IE903930A1 (da)
WO (1) WO1991006861A1 (da)
ZA (1) ZA908778B (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3727610A1 (de) 1987-08-19 1989-03-02 Behringwerke Ag Synthetische peptide, gegen diese gerichtete antikoerper und deren verwendung
US5942443A (en) * 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
US6429025B1 (en) 1996-06-28 2002-08-06 Caliper Technologies Corp. High-throughput screening assay systems in microscale fluidic devices
AUPP460398A0 (en) * 1998-07-10 1998-08-06 Life Therapeutics Limited Lupus anticoagulant
JP2003524187A (ja) * 2000-02-23 2003-08-12 ベッスト−テスト アンパーツゼルスカブ 体液、例えば尿におけるマーカーと血液凝固活性とを相互関連づけるための方法
US20020098516A1 (en) * 2000-10-03 2002-07-25 Boystown National Research Hospital Immunodiagnostic determination of usher syndrome type IIA
DE10354403A1 (de) 2003-11-20 2005-06-23 Dade Behring Marburg Gmbh Gegen das Prothrombin-Fragment F 1+2 gerichtete Antikörper, ihre Herstellung und Verwendung
DE102004042124B4 (de) * 2004-08-30 2006-07-06 Dade Behring Marburg Gmbh Homogenes Verfahren zur Bestimmung eines Analyten in Gegenwart eines Überschusses von kreuzreagierenden Substanzen
KR100967614B1 (ko) * 2008-03-14 2010-07-05 주식회사 바이오인프라 Ｄｅｓ－Ｒ 프로트롬빈 활성 펩티드 단편 Ｆ２의 혈청 내농도 측정을 통한 암의 진단 및 스크리닝 방법
DE102008049601A1 (de) 2008-09-30 2010-04-01 Siemens Healthcare Diagnostics Products Gmbh Antikörper zur Bestimmung des Prothrombin-Fragments F2/F1+2 in einem homogenen Immunoassay
WO2010141131A1 (en) 2009-06-04 2010-12-09 Lockheed Martin Corporation Multiple-sample microfluidic chip for dna analysis
GB2497501A (en) 2010-10-15 2013-06-12 Lockheed Corp Micro fluidic optic design
US9322054B2 (en) 2012-02-22 2016-04-26 Lockheed Martin Corporation Microfluidic cartridge
EP4239338A1 (de) 2022-03-03 2023-09-06 Siemens Healthcare Diagnostics Products GmbH Globaltest zur feststellung des status des blutgerinnungssystems
US20260086394A1 (en) 2022-04-26 2026-03-26 Essilor International Photochromic optical article having a mirror coating
EP4325224A1 (de) 2022-08-18 2024-02-21 Siemens Healthcare Diagnostics Products GmbH Thrombozytenaktivierungstest zur diagnose einer heparin-induzierten thrombozytopenie

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3727610A1 (de) * 1987-08-19 1989-03-02 Behringwerke Ag Synthetische peptide, gegen diese gerichtete antikoerper und deren verwendung

Also Published As

Publication number Publication date
EP0594576A1 (en) 1994-05-04
DE69033220D1 (de) 1999-08-26
JPH05504473A (ja) 1993-07-15
US5830681A (en) 1998-11-03
ATE182366T1 (de) 1999-08-15
JP2918688B2 (ja) 1999-07-12
DE69033220T2 (de) 2000-01-20
ZA908778B (en) 1991-10-30
AU6956391A (en) 1991-05-31
EP0594576A4 (en) 1993-03-15
WO1991006861A1 (en) 1991-05-16
FI922017L (fi) 1992-05-05
CA2071211C (en) 2003-02-18
KR100202773B1 (ko) 1999-06-15
GR3031607T3 (en) 2000-01-31
AU655918B2 (en) 1995-01-19
EP0594576B1 (en) 1999-07-21
FI922017A0 (fi) 1992-05-05
DK0594576T3 (da) 2000-02-07
ES2136598T3 (es) 1999-12-01
IE903930A1 (en) 1991-05-08
CA2071211A1 (en) 1991-05-07

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