FI66009C - Foerfarande foer framstaellning av antivirala arylalkyl- och aryloxialkylfosfonater - Google Patents

Foerfarande foer framstaellning av antivirala arylalkyl- och aryloxialkylfosfonater Download PDF

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Publication number
FI66009C
FI66009C FI791718A FI791718A FI66009C FI 66009 C FI66009 C FI 66009C FI 791718 A FI791718 A FI 791718A FI 791718 A FI791718 A FI 791718A FI 66009 C FI66009 C FI 66009C
Authority
FI
Finland
Prior art keywords
hexyl
compound
formula
phosphonate
diethyl
Prior art date
Application number
FI791718A
Other languages
English (en)
Finnish (fi)
Other versions
FI791718A7 (fi
FI66009B (fi
Inventor
Guy Dominic Diana
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of FI791718A7 publication Critical patent/FI791718A7/fi
Application granted granted Critical
Publication of FI66009B publication Critical patent/FI66009B/fi
Publication of FI66009C publication Critical patent/FI66009C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4056—Esters of arylalkanephosphonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/40—Esters thereof
    • C07F9/4003—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/4006—Esters of acyclic acids which can have further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI791718A 1978-06-05 1979-05-29 Foerfarande foer framstaellning av antivirala arylalkyl- och aryloxialkylfosfonater FI66009C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/912,502 US4182759A (en) 1978-06-05 1978-06-05 Arylalkyl and aryloxyalkyl phosphonates and use as antiviral agents
US91250278 1978-06-05

Publications (3)

Publication Number Publication Date
FI791718A7 FI791718A7 (fi) 1979-12-06
FI66009B FI66009B (fi) 1984-04-30
FI66009C true FI66009C (fi) 1984-08-10

Family

ID=25432033

Family Applications (1)

Application Number Title Priority Date Filing Date
FI791718A FI66009C (fi) 1978-06-05 1979-05-29 Foerfarande foer framstaellning av antivirala arylalkyl- och aryloxialkylfosfonater

Country Status (27)

Country Link
US (1) US4182759A (de)
JP (1) JPS54160348A (de)
KR (1) KR840002462B1 (de)
AR (1) AR223343A1 (de)
AT (1) AT373897B (de)
AU (1) AU528266B2 (de)
BE (1) BE876680A (de)
CA (1) CA1108176A (de)
CH (1) CH641188A5 (de)
DE (1) DE2922054A1 (de)
DK (1) DK223579A (de)
ES (2) ES481227A1 (de)
FI (1) FI66009C (de)
FR (1) FR2428047A1 (de)
GB (1) GB2022589B (de)
IE (1) IE48334B1 (de)
IL (1) IL57300A (de)
IT (1) IT1203687B (de)
LU (1) LU81350A1 (de)
MX (1) MX6013E (de)
NL (1) NL7904265A (de)
NO (1) NO791770L (de)
NZ (1) NZ190460A (de)
PH (2) PH14734A (de)
PT (1) PT69693A (de)
SE (1) SE7904687L (de)
ZA (1) ZA792447B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2043073B (en) * 1979-02-13 1983-05-11 Symphar Sa Mono-and diphosphonate compounds
US4556520A (en) * 1982-10-08 1985-12-03 Zoecon Corporation 2-Nitro(cyano)phenyloxy(thio)alkyl phosphinates or phosphonates
DE4003054A1 (de) * 1990-02-02 1991-08-08 Hoechst Ag Verwendung von benzylphosphonsaeurederivaten zur behandlung von durch viren verursachte krankheiten
CN102781462A (zh) * 2009-08-27 2012-11-14 伊皮芬尼生物科学公司 新的核苷膦酸酯及类似物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2934507A (en) * 1954-06-18 1960-04-26 Monsanto Chemicals Polyvinyl chloride resins stabilized with mixtures of phosphonate esters, epoxy compounds and metallic salts of fatty acids
US3917718A (en) * 1972-06-22 1975-11-04 Sterling Drug Inc Cyclopropyl carbinol derivatives
US4031246A (en) * 1973-07-23 1977-06-21 Sterling Drug Inc. Aryloxyalkyl diketones

Also Published As

Publication number Publication date
LU81350A1 (fr) 1979-12-07
AU4724979A (en) 1979-12-13
KR830001644A (ko) 1983-05-18
IL57300A0 (en) 1979-09-30
DK223579A (da) 1979-12-06
AR223343A1 (es) 1981-08-14
FR2428047A1 (fr) 1980-01-04
CA1108176A (en) 1981-09-01
PH14734A (en) 1981-11-19
NL7904265A (nl) 1979-12-07
IL57300A (en) 1983-06-15
GB2022589B (en) 1982-10-13
FI791718A7 (fi) 1979-12-06
ZA792447B (en) 1980-06-25
ES489590A0 (es) 1981-02-16
JPS54160348A (en) 1979-12-19
AT373897B (de) 1984-02-27
SE7904687L (sv) 1979-12-06
IT7923000A0 (it) 1979-05-25
CH641188A5 (fr) 1984-02-15
PT69693A (en) 1979-06-01
US4182759A (en) 1980-01-08
ES8103110A1 (es) 1981-02-16
NZ190460A (en) 1981-07-13
ES481227A1 (es) 1980-09-01
MX6013E (es) 1984-09-24
IT1203687B (it) 1989-02-15
NO791770L (no) 1979-12-06
US4182759B1 (de) 1984-12-18
PH15469A (en) 1983-01-24
DE2922054A1 (de) 1979-12-06
KR840002462B1 (ko) 1984-12-29
IE48334B1 (en) 1984-12-12
FI66009B (fi) 1984-04-30
AU528266B2 (en) 1983-04-21
IE790945L (en) 1979-12-05
FR2428047B1 (de) 1984-08-17
ATA401779A (de) 1983-07-15
BE876680A (fr) 1979-11-30
GB2022589A (en) 1979-12-19

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Legal Events

Date Code Title Description
FD Application lapsed
MM Patent lapsed

Owner name: STERLING DRUG INC