FI830879A7 - Menetelmä haavauman vastaisina lääkeaineina käyttökelpoisten tiatsolijohdannaisten valmistamiseksi. - Google Patents

Menetelmä haavauman vastaisina lääkeaineina käyttökelpoisten tiatsolijohdannaisten valmistamiseksi. Download PDF

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Publication number
FI830879A7
FI830879A7 FI830879A FI830879A FI830879A7 FI 830879 A7 FI830879 A7 FI 830879A7 FI 830879 A FI830879 A FI 830879A FI 830879 A FI830879 A FI 830879A FI 830879 A7 FI830879 A7 FI 830879A7
Authority
FI
Finland
Prior art keywords
derivatives useful
thiazole derivatives
antiulcer drugs
preparing thiazole
preparing
Prior art date
Application number
FI830879A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI830879A0 (fi
FI830879L (fi
Inventor
Richard Paul Pioch
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI830879A0 publication Critical patent/FI830879A0/fi
Publication of FI830879L publication Critical patent/FI830879L/fi
Publication of FI830879A7 publication Critical patent/FI830879A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/194—Radicals derived from thio- or thiono carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Earth Drilling (AREA)
  • Inert Electrodes (AREA)
  • Treating Waste Gases (AREA)
  • Fats And Perfumes (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Supply Devices, Intensifiers, Converters, And Telemotors (AREA)
FI830879A 1982-03-19 1983-03-16 Menetelmä haavauman vastaisina lääkeaineina käyttökelpoisten tiatsolijohdannaisten valmistamiseksi. FI830879A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/360,034 US4474794A (en) 1982-03-19 1982-03-19 N-Thiazolylmethylthioalkyl-N1 -alkenyl (or alkynyl)guanidines and related compounds

Publications (3)

Publication Number Publication Date
FI830879A0 FI830879A0 (fi) 1983-03-16
FI830879L FI830879L (fi) 1983-09-20
FI830879A7 true FI830879A7 (fi) 1983-09-20

Family

ID=23416322

Family Applications (1)

Application Number Title Priority Date Filing Date
FI830879A FI830879A7 (fi) 1982-03-19 1983-03-16 Menetelmä haavauman vastaisina lääkeaineina käyttökelpoisten tiatsolijohdannaisten valmistamiseksi.

Country Status (22)

Country Link
US (1) US4474794A (cs)
EP (1) EP0091220B1 (cs)
JP (1) JPS58170773A (cs)
KR (1) KR840004091A (cs)
AT (1) ATE27156T1 (cs)
AU (1) AU1254583A (cs)
CA (1) CA1190547A (cs)
CS (1) CS236788B2 (cs)
DD (1) DD207376A5 (cs)
DE (1) DE3371514D1 (cs)
DK (1) DK91083A (cs)
ES (1) ES520791A0 (cs)
FI (1) FI830879A7 (cs)
GB (1) GB2116973B (cs)
GR (1) GR77882B (cs)
IL (1) IL68152A0 (cs)
NZ (1) NZ203605A (cs)
PH (1) PH18504A (cs)
PL (1) PL241066A1 (cs)
PT (1) PT76397B (cs)
RO (1) RO85385B (cs)
ZA (1) ZA831882B (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL80961A0 (en) * 1985-12-18 1987-03-31 Lilly Co Eli Synthesis of nizatidine
EP0285681B1 (de) * 1987-04-06 1993-03-10 HEUMANN PHARMA GMBH & CO Verfahren zur Herstellung von Nitroethenderivaten
NL9000132A (nl) * 1990-01-19 1991-08-16 Cedona Pharm Bv Nieuwe thiazoolderivaten.
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4200578A (en) * 1978-12-18 1980-04-29 Bristol-Myers Company Thiazole derivatives
US4375547A (en) * 1980-10-02 1983-03-01 Eli Lilly And Company N-Methyl-N'-2-([(2-dimethylaminomethyl)-4-thiazolyl]methylthio)ethyl 2-nitro-1,1-ethenediamine

Also Published As

Publication number Publication date
US4474794A (en) 1984-10-02
PT76397A (en) 1983-04-01
DD207376A5 (de) 1984-02-29
EP0091220A3 (en) 1984-05-23
FI830879A0 (fi) 1983-03-16
RO85385B (ro) 1984-11-30
PL241066A1 (en) 1985-01-02
FI830879L (fi) 1983-09-20
NZ203605A (en) 1985-10-11
RO85385A (ro) 1984-11-25
EP0091220B1 (en) 1987-05-13
DK91083A (da) 1983-09-20
PH18504A (en) 1985-08-02
JPS58170773A (ja) 1983-10-07
EP0091220A2 (en) 1983-10-12
IL68152A0 (en) 1983-06-15
AU1254583A (en) 1983-09-22
ZA831882B (en) 1984-11-28
GB8307201D0 (en) 1983-04-20
CS236788B2 (en) 1985-05-15
KR840004091A (ko) 1984-10-06
ES8405386A1 (es) 1984-06-01
GR77882B (cs) 1984-09-25
GB2116973B (en) 1985-08-29
CA1190547A (en) 1985-07-16
DK91083D0 (da) 1983-02-25
DE3371514D1 (en) 1987-06-19
PT76397B (en) 1986-02-04
GB2116973A (en) 1983-10-05
ATE27156T1 (de) 1987-05-15
ES520791A0 (es) 1984-06-01

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: ELI LILLY AND COMPANY