FI865004L - 5-amino- och 5-hydroxi-6,8 -difluorkinoloner saosom antibakteriska aemnen. - Google Patents

5-amino- och 5-hydroxi-6,8 -difluorkinoloner saosom antibakteriska aemnen. Download PDF

Info

Publication number
FI865004L
FI865004L FI865004A FI865004A FI865004L FI 865004 L FI865004 L FI 865004L FI 865004 A FI865004 A FI 865004A FI 865004 A FI865004 A FI 865004A FI 865004 L FI865004 L FI 865004L
Authority
FI
Finland
Prior art keywords
difluorquinoloner
aemnen
saosom
hydroxi
och
Prior art date
Application number
FI865004A
Other languages
English (en)
Finnish (fi)
Other versions
FI865004A7 (fi
FI865004A0 (fi
Inventor
Ashok K Trehan
Joseph P Sanchez
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/808,122 external-priority patent/US4668680A/en
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of FI865004A0 publication Critical patent/FI865004A0/fi
Publication of FI865004L publication Critical patent/FI865004L/fi
Publication of FI865004A7 publication Critical patent/FI865004A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI865004A 1985-12-12 1986-12-08 5-amino- ja 5-hydroksi-6,8 -difluorikinolonit antibakteerisina aineina. FI865004A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/808,122 US4668680A (en) 1985-12-12 1985-12-12 5-amino-6,8-difluoroquinolones as antibacterial agents
US06/918,568 US4977154A (en) 1985-12-12 1986-10-20 5-amino and 5-hydroxy-6-fluoroquinolones as antibacterial agents

Publications (3)

Publication Number Publication Date
FI865004A0 FI865004A0 (fi) 1986-12-08
FI865004L true FI865004L (fi) 1987-06-13
FI865004A7 FI865004A7 (fi) 1987-06-13

Family

ID=27123084

Family Applications (1)

Application Number Title Priority Date Filing Date
FI865004A FI865004A7 (fi) 1985-12-12 1986-12-08 5-amino- ja 5-hydroksi-6,8 -difluorikinolonit antibakteerisina aineina.

Country Status (16)

Country Link
US (1) US4977154A (da)
EP (1) EP0226961B1 (da)
KR (1) KR900000555B1 (da)
CN (1) CN1013114B (da)
AU (1) AU591732B2 (da)
DE (1) DE3679793D1 (da)
DK (1) DK166493B1 (da)
ES (1) ES2039198T3 (da)
FI (1) FI865004A7 (da)
GR (1) GR3002129T3 (da)
HU (1) HU203231B (da)
IE (1) IE59261B1 (da)
IL (1) IL80933A (da)
NO (1) NO865013L (da)
OA (1) OA08561A (da)
PT (1) PT83909B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU594983B2 (en) * 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof
EP0242789A3 (en) * 1986-04-25 1990-09-05 Dainippon Pharmaceutical Co., Ltd. Novel quinoline derivates and processes for preparation thereof
DE3711193A1 (de) * 1987-04-02 1988-10-13 Bayer Ag 5-substituierte chinolon- und naphthyridoncarbonsaeure-derivate
US4933335A (en) * 1987-08-07 1990-06-12 Warner-Lambert Company Quinolones as antibacterial agents
US4780468A (en) * 1987-08-07 1988-10-25 Warner-Lambert Company 8-trifluoromethyl quinolones as antibacterial agents
US4929613A (en) * 1987-08-26 1990-05-29 Warner-Lambert Company Antibacterial agents
EP0339406A1 (en) * 1988-04-19 1989-11-02 Hokuriku Pharmaceutical Co.,Ltd Quinoline-3-carboxylic acid derivatives, process for preparing the same, and composition exhibiting excellent antibacterial effect containing the same
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
FI95130C (fi) * 1988-07-20 1995-12-27 Sankyo Co Menetelmä lääkeaineena käyttökelpoisten 4-oksokinoliini-3-karboksyylihapon johdannaisten valmistamiseksi
DK0525057T3 (da) 1990-04-18 2000-07-31 Procter & Gamble Pharma Antimikrobielle quinolonyllactamer
DE4019023A1 (de) * 1990-06-14 1991-12-19 Bayer Ag Verfahren zur herstellung von chinolincarbonsaeuren
CA2194435A1 (en) * 1994-07-18 1996-02-01 Ube Industries, Ltd. Trifluoromethylquinolinecarboxylic acid derivative
US5866150A (en) * 1996-03-20 1999-02-02 Aquaculture Technology Incorporated Antibacterially active extracts from the marine algae chaetoceros and methods of use
IN186245B (da) 1997-09-19 2001-07-14 Ranbaxy Lab Ltd
CN1091103C (zh) * 1999-04-02 2002-09-18 中国科学院上海药物研究所 一类喹诺酮类化合物及它的制备和其用途
ATE407121T1 (de) * 2000-02-09 2008-09-15 Daiichi Sankyo Co Ltd Gegen säurebeständige bakterien wirksame antibakterielle mittel die pyridincarbonsäuren als aktiven wirkstoff enthalten
DE102004035203A1 (de) * 2004-07-21 2006-02-16 Bayer Healthcare Ag Substituierte Chinolone
US8524735B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
CN100415212C (zh) * 2006-07-21 2008-09-03 哈药集团制药总厂 一种含乳酸卡德沙星的口服制剂
CA2739897C (en) 2008-10-07 2017-10-03 Mpex Pharmaceuticals, Inc. Aerosol fluoroquinolone formulations for improved pharmacokinetics
US8629139B2 (en) 2008-10-07 2014-01-14 Mpex Pharmaceuticals, Inc. Topical use of Levofloxacin for reducing lung inflammation
DK2473170T3 (da) 2009-09-04 2019-08-12 Horizon Orphan Llc Anvendelse af aerosoliseret levofloxacin til behandling af cystisk fibrose
CN104557896A (zh) * 2013-10-18 2015-04-29 沈敬山 布瑞哌唑、其关键中间体及其盐的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2808070A1 (de) * 1978-02-24 1979-08-30 Bayer Ag Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten
DE3248506A1 (de) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7(alkyl-1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
EP0160578B1 (en) * 1984-02-17 1989-11-23 Daiichi Seiyaku Co., Ltd. 1,8-naphthyridine derivatives
US4604401A (en) * 1984-07-20 1986-08-05 Warner-Lambert Company Antibacterial agents III
JPS61205258A (ja) * 1985-03-08 1986-09-11 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体及びその製造方法
AU594983B2 (en) * 1985-10-29 1990-03-22 Dainippon Pharmaceutical Co. Ltd. Novel quinoline derivatives and processes for preparation thereof

Also Published As

Publication number Publication date
HUT42470A (en) 1987-07-28
PT83909A (en) 1987-01-01
AU591732B2 (en) 1989-12-14
AU6587986A (en) 1987-06-18
KR870006034A (ko) 1987-07-08
KR900000555B1 (ko) 1990-01-31
EP0226961A1 (en) 1987-07-01
EP0226961B1 (en) 1991-06-12
FI865004A7 (fi) 1987-06-13
CN86108942A (zh) 1987-11-04
CN1013114B (zh) 1991-07-10
IE59261B1 (en) 1994-01-26
OA08561A (en) 1988-09-30
FI865004A0 (fi) 1986-12-08
US4977154A (en) 1990-12-11
IL80933A0 (en) 1987-03-31
GR3002129T3 (en) 1992-12-30
DK166493B1 (da) 1993-06-01
IE863104L (en) 1987-06-12
NO865013L (no) 1987-06-15
DE3679793D1 (de) 1991-07-18
ES2039198T3 (es) 1993-09-16
HU203231B (en) 1991-06-28
NO865013D0 (no) 1986-12-11
DK590586A (da) 1987-06-13
PT83909B (pt) 1989-05-12
DK590586D0 (da) 1986-12-09
IL80933A (en) 1991-06-10

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: WARNER-LAMBERT COMPANY