FI881305L - Behandling av maenniskans virusinfektioner med en kombination av dsrna och virusinhibitorer. - Google Patents

Behandling av maenniskans virusinfektioner med en kombination av dsrna och virusinhibitorer. Download PDF

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Publication number
FI881305L
FI881305L FI881305A FI881305A FI881305L FI 881305 L FI881305 L FI 881305L FI 881305 A FI881305 A FI 881305A FI 881305 A FI881305 A FI 881305A FI 881305 L FI881305 L FI 881305L
Authority
FI
Finland
Prior art keywords
virusinhibitorer
virusinfektioner
maenniskans
behandling
kombination
Prior art date
Application number
FI881305A
Other languages
English (en)
Finnish (fi)
Other versions
FI881305A7 (fi
FI881305A0 (fi
Inventor
William A Carter
Original Assignee
Hem Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hem Res Inc filed Critical Hem Res Inc
Publication of FI881305A0 publication Critical patent/FI881305A0/fi
Publication of FI881305A7 publication Critical patent/FI881305A7/fi
Publication of FI881305L publication Critical patent/FI881305L/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
FI881305A 1987-03-23 1988-03-18 Behandling av maenniskans virusinfektioner med en kombination av dsrna och virusinhibitorer. FI881305L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2882387A 1987-03-23 1987-03-23
US07/125,097 US4950652A (en) 1987-03-23 1987-11-25 dsRNAs for combination therapy in the treatment of viral diseases

Publications (3)

Publication Number Publication Date
FI881305A0 FI881305A0 (fi) 1988-03-18
FI881305A7 FI881305A7 (fi) 1988-09-24
FI881305L true FI881305L (fi) 1988-09-24

Family

ID=26704119

Family Applications (1)

Application Number Title Priority Date Filing Date
FI881305A FI881305L (fi) 1987-03-23 1988-03-18 Behandling av maenniskans virusinfektioner med en kombination av dsrna och virusinhibitorer.

Country Status (21)

Country Link
US (1) US4950652A (fr)
EP (1) EP0286224B1 (fr)
JP (1) JP2656938B2 (fr)
KR (1) KR960013435B1 (fr)
CN (1) CN1049357C (fr)
AU (1) AU1256288A (fr)
CA (1) CA1316832C (fr)
DE (1) DE3876125T2 (fr)
DK (1) DK156688A (fr)
ES (1) ES2066782T3 (fr)
FI (1) FI881305L (fr)
GR (1) GR3006340T3 (fr)
HU (1) HUT46542A (fr)
IE (1) IE63823B1 (fr)
IL (1) IL85646A (fr)
NO (1) NO881246L (fr)
NZ (1) NZ223868A (fr)
OA (1) OA08724A (fr)
PH (1) PH23333A (fr)
PT (1) PT87039B (fr)
RU (1) RU2016572C1 (fr)

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US6130206A (en) * 1980-07-07 2000-10-10 Hem Research, Inc. Treating viral infections associated with chronic fatigue with dsRNA
US9309574B1 (en) 1984-08-22 2016-04-12 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Molecular cloning of HIV-1 from immortalized cell lines
US5091374A (en) * 1987-07-17 1992-02-25 Hem Research Inc. Double-stranded RNA correction of abnormalities in circulating immune complexes and monocyte function
US5906980A (en) * 1987-07-17 1999-05-25 Hem Research Inc. Treatment of hepatitis with mismatched dsRNA
US5712257A (en) * 1987-08-12 1998-01-27 Hem Research, Inc. Topically active compositions of mismatched dsRNAs
US4963532A (en) * 1987-11-25 1990-10-16 Hem Research, Inc. dsRNA-based prevention of viral escape
US4960592A (en) * 1989-04-17 1990-10-02 Lanocare Laboratories Lanolin and lanolin oil skin treatment composition
US5132292A (en) * 1990-05-25 1992-07-21 Hem Research, Inc. Treatment of viral hepatitis
US5614504A (en) * 1990-08-01 1997-03-25 The University Of South Florida Method of making inosine monophosphate derivatives and immunopotentiating uses thereof
US6703418B2 (en) * 1991-02-26 2004-03-09 Unimed Pharmaceuticals, Inc. Appetite stimulation and induction of weight gain in patients suffering from symptomatic HIV infection
AU671800B2 (en) * 1991-04-16 1996-09-12 Hem Pharmaceuticals Corp. Abrogation of viral resistance to nucleoside analogues by double-stranded RNAs
GB9108085D0 (en) * 1991-04-16 1991-06-05 Scras Complexes of polyadenylic acid with polyuridylic acid
AU2268892A (en) * 1991-07-16 1993-02-23 Hem Pharmaceuticals Corp. Modulation and diagnosis of cytokine dysfunctions
US20030207813A1 (en) * 1996-12-09 2003-11-06 G.D. Searle Retroviral protease inhibitor combinations
US5766582A (en) * 1994-10-11 1998-06-16 Schering Corporation Stable, aqueous alfa interferon solution formulations
AU723537B2 (en) * 1995-06-07 2000-08-31 Trimeris Inc. The treatment of HIV and other viral infections using combinatorial therapy
US5834443A (en) * 1996-05-21 1998-11-10 Masiello; Domenick J. Composition and method for treating herpes simplex
RU2123339C1 (ru) * 1996-06-18 1998-12-20 Государственный научный центр вирусологии и биотехнологии "Вектор" Противовирусное средство
GB9622681D0 (en) * 1996-10-31 1997-01-08 Glaxo Group Ltd Pharmaceutical compositions
EP0998293A4 (fr) * 1997-01-17 2002-07-17 Icn Pharmaceuticals Traitements lies a la cytokine destines a des affections
LT4475B (lt) * 1997-02-28 1999-02-25 Virmantas Stunžėnas Informacinės ribonukleino rūgšties panaudojimas vaistinėse medžiagose, skirtose padidinti šios ribonukleino rūgšties koduojamo baltymo kiekį paciento ląstelėse
FR2766715B1 (fr) * 1997-08-04 2001-02-16 Scras Produit comprenant au moins de l'arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique simultanee, separee ou etalee dans le temps, dans le traitement d'une maladie virale
AR013269A1 (es) * 1997-08-04 2000-12-13 Scras Producto que contiene por lo menos un rna de doble filamento combinado con por lo menos un agente anti-viral, para la utilizacion terapeutica en eltratamiento de una enfermedad viral, en especial de la hepatitis viral
FR2768344B1 (fr) * 1997-08-26 2001-02-16 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale
FR2768345B1 (fr) * 1997-09-17 2001-05-04 Scras Produit comprenant au moins un arn double brin en association avec au moins un agent anti-viral pour une utilisation therapeutique dans le traitement d'une maladie virale, notamment d'une hepatite virale
FR2766711B1 (fr) * 1997-08-04 2001-02-02 Sod Conseils Rech Applic Produit comprenant au moins un arn double brin en association avec au moins un devire du 6-benzyluracile pour une utilisation therapeutique simultanee, separee ou etalee dans le temps
US6506559B1 (en) * 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
CN101818145A (zh) 1998-03-20 2010-09-01 联邦科学和工业研究组织 控制基因表达
FR2776927B1 (fr) * 1998-04-07 2002-07-05 Univ Paris Curie Compositions pour la vectorisation de molecules
CA2361201A1 (fr) 1999-01-28 2000-08-03 Medical College Of Georgia Research Institute, Inc. Composition et methode destinees a l'attenuation in vivo et in vitro de l'expression genique utilisant de l'arn double brin
US6977245B2 (en) 1999-04-12 2005-12-20 The United States Of America As Represented By The Department Of Health And Human Services Oligodeoxynucleotide and its use to induce an immune response
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
RU2172631C2 (ru) * 1999-10-08 2001-08-27 Государственный научный центр вирусологии и биотехнологии "Вектор" Индуктор интерферона пролонгированного действия
AU2001227889A1 (en) 2000-01-14 2001-07-24 The United States of America, represented by The Secretary, Department of Health & Human Services Oligodeoxynucleotide and its use to induce an immune response
US7638496B2 (en) 2000-02-15 2009-12-29 Valeant Pharmaceuticals North America Nucleoside analogs with carboxamidine modified monocyclic base
US20080242627A1 (en) * 2000-08-02 2008-10-02 University Of Southern California Novel rna interference methods using dna-rna duplex constructs
DE10100588A1 (de) * 2001-01-09 2002-07-18 Ribopharma Ag Verfahren zur Hemmung der Expression eines Zielgens
CA2369944A1 (fr) 2001-01-31 2002-07-31 Nucleonics Inc. Utilisation de l'inhibition genetique post-transcriptionnelle pour identifier les sequences d'acides nucleiques qui modulent la fonction d'une cellule
US7666674B2 (en) 2001-07-27 2010-02-23 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo
WO2003020884A2 (fr) 2001-08-14 2003-03-13 The Government Of The United States Of America As Represented By The Secretary Of Health And Human Services Procede de generation rapide de cellules dentritique matures
WO2003051301A2 (fr) * 2001-12-14 2003-06-26 Hemispherx Biopharma Utilisation d'arn bicatenaire lors d'une intervention therapeutique strategique d'une therapie antiretrovirale hautement active
US8466116B2 (en) 2001-12-20 2013-06-18 The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services Use of CpG oligodeoxynucleotides to induce epithelial cell growth
WO2003054161A2 (fr) 2001-12-20 2003-07-03 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Utilisation d'oligodeoxynucleotides cpg en vue d'induire l'angiogenese
ATE556714T1 (de) 2002-02-01 2012-05-15 Life Technologies Corp Doppelsträngige oligonukleotide
US20060009409A1 (en) 2002-02-01 2006-01-12 Woolf Tod M Double-stranded oligonucleotides
EP3006043B1 (fr) 2002-04-04 2019-05-29 Zoetis Belgium S.A. Oligoribonucleotides immunostimulants contenant de la guanine et de l'uracile
US8263091B2 (en) 2002-09-18 2012-09-11 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method of treating and preventing infections in immunocompromised subjects with immunostimulatory CpG oligonucleotides
WO2005009337A2 (fr) * 2003-05-16 2005-02-03 Hemispherx Biopharma Traitement du syndrome respiratoire aigu grave
US20060035859A1 (en) * 2003-05-16 2006-02-16 Hemispherx Biopharma Treating severe and acute viral infections
US20050113292A1 (en) * 2003-07-18 2005-05-26 Vanderbilt University Compositions of protein mimetics and methods of using same against HIV-1, SARS-coV and the like
CN1867355A (zh) * 2003-08-11 2006-11-22 财团法人阪大微生物病研究会 包含诱导粘膜免疫的佐剂的新型疫苗
RU2272631C2 (ru) * 2004-04-20 2006-03-27 Государственный научный центр вирусологии и биотехнологии "Вектор" (ГНЦ ВБ "Вектор") Синергическая композиция для ингибирования вич
DE202005004135U1 (de) * 2005-03-11 2005-05-19 Klocke Verpackungs-Service Gmbh Mehrkomponentenverpackung mit Applikator
JP4538522B2 (ja) * 2005-11-25 2010-09-08 コーリー ファーマシューティカル ゲーエムベーハー 免疫刺激性オリゴリボヌクレオチド
US8075877B2 (en) 2006-03-08 2011-12-13 Hemispherx Biopharma Broad spectrum immune and antiviral gene modulation by oral interferon
CA2644670A1 (fr) * 2006-03-08 2008-05-08 Hemispherx Biopharma Inc. Modulation de genes immune et antivirale a large spectre par administration orale d'interferon
NZ584968A (en) * 2007-10-29 2012-11-30 Cipla Ltd Novel antiretroviral combination comprising ritonavir and atazanavir
WO2009102496A2 (fr) * 2008-02-15 2009-08-20 Hemispherx Biopharma, Inc. Agoniste sélectif du récepteur 3 de type toll

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EP0113162B1 (fr) * 1982-09-16 1989-07-19 Hem Research, Inc. Effet antinéoplastiques des acides ds-ribonucléiques sur les cellules des tumeurs
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
ATE113603T1 (de) * 1985-03-16 1994-11-15 Wellcome Found Antivirale nukleoside.
US4795744A (en) * 1986-07-17 1989-01-03 Hem Research, Inc. Modulation of AIDS virus-related events by double-stranded RNAS
CA1326450C (fr) * 1985-08-26 1994-01-25 William A. Carter Modulation des manifestations associees au virus du sida au moyen d'arn a double brin

Also Published As

Publication number Publication date
IE880839L (en) 1988-09-23
US4950652A (en) 1990-08-21
EP0286224A3 (en) 1988-12-07
FI881305A7 (fi) 1988-09-24
ES2066782T3 (es) 1995-03-16
IL85646A0 (en) 1988-08-31
DK156688A (da) 1988-09-24
AU1256288A (en) 1988-09-22
DE3876125D1 (de) 1993-01-07
PT87039A (pt) 1988-04-01
JP2656938B2 (ja) 1997-09-24
EP0286224B1 (fr) 1992-11-25
FI881305A0 (fi) 1988-03-18
NO881246L (no) 1988-09-26
OA08724A (fr) 1989-03-31
IL85646A (en) 1993-05-13
NO881246D0 (no) 1988-03-21
DE3876125T2 (de) 1993-06-09
GR3006340T3 (fr) 1993-06-21
HUT46542A (en) 1988-11-28
PH23333A (en) 1989-07-14
CN1049357C (zh) 2000-02-16
KR960013435B1 (ko) 1996-10-05
NZ223868A (en) 1991-02-26
EP0286224A2 (fr) 1988-10-12
DK156688D0 (da) 1988-03-22
CN88101606A (zh) 1988-12-28
RU2016572C1 (ru) 1994-07-30
PT87039B (pt) 1992-11-30
KR880010777A (ko) 1988-10-24
IE63823B1 (en) 1995-06-14
CA1316832C (fr) 1993-04-27
JPS6425A (en) 1989-01-05

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Legal Events

Date Code Title Description
FD Application lapsed

Owner name: HEM RESEARCH, INC.