FI89457C - Foerfarande foer framstaellning av ett preparat som innehaoller ett aluminiumsalt av en sackarossulfatester - Google Patents

Foerfarande foer framstaellning av ett preparat som innehaoller ett aluminiumsalt av en sackarossulfatester Download PDF

Info

Publication number: FI89457C
Authority: FI; Finland
Prior art keywords: ett; polyethylene glycol; sucralfate; sackarossulfatester; aluminiumsalt
Prior art date: 1986-04-30

Application number

FI871852A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI871852A0 (fi

FI89457B (fi

FI871852L (fi

Inventor

Yoshimitsu Iida

Minoru Machida

Original Assignee

Chugai Pharmaceutical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-04-30

Filing date

1987-04-28

Publication date

1993-10-11

1987-04-28 Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd

1987-04-28 Publication of FI871852A0 publication Critical patent/FI871852A0/fi

1987-10-31 Publication of FI871852L publication Critical patent/FI871852L/fi

1993-06-30 Application granted granted Critical

1993-06-30 Publication of FI89457B publication Critical patent/FI89457B/fi

1993-10-11 Publication of FI89457C publication Critical patent/FI89457C/fi

Links

159000000013 aluminium salts Chemical class 0.000 title 1
229910000329 aluminium sulfate Inorganic materials 0.000 title 1
MNQYNQBOVCBZIQ-JQOFMKNESA-A sucralfate Chemical compound O[Al](O)OS(=O)(=O)O[C@@H]1[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](COS(=O)(=O)O[Al](O)O)O[C@H]1O[C@@]1(COS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)O1 MNQYNQBOVCBZIQ-JQOFMKNESA-A 0.000 claims description 22
229960004291 sucralfate Drugs 0.000 claims description 21
239000002202 Polyethylene glycol Substances 0.000 claims description 14
229920001223 polyethylene glycol Polymers 0.000 claims description 14
238000002360 preparation method Methods 0.000 claims description 11
238000000034 method Methods 0.000 claims description 4
239000000203 mixture Substances 0.000 claims description 4
-1 sucrose sulfate ester Chemical class 0.000 claims description 4
229930006000 Sucrose Natural products 0.000 claims description 3
AZDRQVAHHNSJOQ-UHFFFAOYSA-N alumane Chemical class [AlH3] AZDRQVAHHNSJOQ-UHFFFAOYSA-N 0.000 claims description 3
239000005720 sucrose Substances 0.000 claims description 3
XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims 1
229910052782 aluminium Inorganic materials 0.000 claims 1
238000004519 manufacturing process Methods 0.000 claims 1
230000032683 aging Effects 0.000 description 10
239000008187 granular material Substances 0.000 description 9
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
239000007788 liquid Substances 0.000 description 5
206010052428 Wound Diseases 0.000 description 4
208000027418 Wounds and injury Diseases 0.000 description 4
239000007864 aqueous solution Substances 0.000 description 4
HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 4
239000012927 reference suspension Substances 0.000 description 4
230000000694 effects Effects 0.000 description 3
230000002496 gastric effect Effects 0.000 description 3
230000001133 acceleration Effects 0.000 description 2
230000015556 catabolic process Effects 0.000 description 2
239000001913 cellulose Substances 0.000 description 2
229920002678 cellulose Polymers 0.000 description 2
238000006731 degradation reaction Methods 0.000 description 2
239000012530 fluid Substances 0.000 description 2
235000019359 magnesium stearate Nutrition 0.000 description 2
239000000843 powder Substances 0.000 description 2
VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 1
239000004606 Fillers/Extenders Substances 0.000 description 1
229920003114 HPC-L Polymers 0.000 description 1
229920002153 Hydroxypropyl cellulose Polymers 0.000 description 1
102000057297 Pepsin A Human genes 0.000 description 1
108090000284 Pepsin A Proteins 0.000 description 1
239000000654 additive Substances 0.000 description 1
229940069428 antacid Drugs 0.000 description 1
239000003159 antacid agent Substances 0.000 description 1
230000001458 anti-acid effect Effects 0.000 description 1
239000011230 binding agent Substances 0.000 description 1
239000002775 capsule Substances 0.000 description 1
239000003086 colorant Substances 0.000 description 1
239000007884 disintegrant Substances 0.000 description 1
239000006185 dispersion Substances 0.000 description 1
229940079593 drug Drugs 0.000 description 1
239000003814 drug Substances 0.000 description 1
239000000835 fiber Substances 0.000 description 1
210000001156 gastric mucosa Anatomy 0.000 description 1
238000005469 granulation Methods 0.000 description 1
230000003179 granulation Effects 0.000 description 1
230000035876 healing Effects 0.000 description 1
239000001863 hydroxypropyl cellulose Substances 0.000 description 1
235000010977 hydroxypropyl cellulose Nutrition 0.000 description 1
230000003902 lesion Effects 0.000 description 1
239000000314 lubricant Substances 0.000 description 1
238000005259 measurement Methods 0.000 description 1
229940111202 pepsin Drugs 0.000 description 1
235000004252 protein component Nutrition 0.000 description 1
235000018102 proteins Nutrition 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
239000000243 solution Substances 0.000 description 1
239000000758 substrate Substances 0.000 description 1
239000000725 suspension Substances 0.000 description 1
239000003826 tablet Substances 0.000 description 1
239000012085 test solution Substances 0.000 description 1
238000005303 weighing Methods 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Photoreceptors In Electrophotography (AREA)
Cephalosporin Compounds (AREA)

FI871852A 1986-04-30 1987-04-28 Foerfarande foer framstaellning av ett preparat som innehaoller ett aluminiumsalt av en sackarossulfatester FI89457C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
JP9990186		1986-04-30
JP9990186		1986-04-30

Publications (4)

Publication Number	Publication Date
FI871852A0 FI871852A0 (fi)	1987-04-28
FI871852L FI871852L (fi)	1987-10-31
FI89457B FI89457B (fi)	1993-06-30
FI89457C true FI89457C (fi)	1993-10-11

Family

ID=14259677

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI871852A FI89457C (fi)	1986-04-30	1987-04-28	Foerfarande foer framstaellning av ett preparat som innehaoller ett aluminiumsalt av en sackarossulfatester

Country Status (9)

Country	Link
JP (1)	JP2542210B2 (da)
DE (1)	DE3714159C2 (da)
DK (1)	DK167735B1 (da)
ES (1)	ES2017805A6 (da)
FI (1)	FI89457C (da)
FR (1)	FR2598084B1 (da)
IT (1)	IT1208416B (da)
NO (1)	NO174085C (da)
SE (1)	SE503233C2 (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2735559B2 (ja) *	1988-03-02	1998-04-02	中外製薬株式会社	懸濁液
ATE213635T1 (de) *	1994-04-26	2002-03-15	Chugai Pharmaceutical Co Ltd	Verfahren für die herstellung schmelz-granulierte sucralfatzubereitung
EP0808629A4 (en) *	1995-02-02	1998-03-04	Chugai Pharmaceutical Co Ltd	Sucralfate preparation
ES2112765B1 (es) *	1995-08-02	1999-03-01	Cantabria Ind Farmaceutica Sa	Procedimiento para la obtencion de formulaciones de constraste radiologico, para exploraciones gastrointestinales de uso extemporaneo y directo.
WO2011102505A1 (ja) *	2010-02-22	2011-08-25	第一三共株式会社	経口用徐放性固形製剤
ES2706880T3 (es)	2010-02-22	2019-04-01	Daiichi Sankyo Co Ltd	Preparación sólida de liberación sostenida para uso oral
CA2883077C (en)	2012-09-03	2017-03-07	Daiichi Sankyo Company, Limited	Hydromorphone hydrochloride-containing oral sustained-release pharmaceutical composition

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3430809A1 (de) *	1984-08-22	1986-03-06	Merck Patent Gmbh, 6100 Darmstadt	Sucralfat-suspension

1987
- 1987-04-28 DE DE3714159A patent/DE3714159C2/de not_active Expired - Lifetime
- 1987-04-28 FI FI871852A patent/FI89457C/fi not_active IP Right Cessation
- 1987-04-28 NO NO871759A patent/NO174085C/no unknown
- 1987-04-29 IT IT8767365A patent/IT1208416B/it active
- 1987-04-29 SE SE8701787A patent/SE503233C2/sv not_active IP Right Cessation
- 1987-04-29 DK DK218587A patent/DK167735B1/da not_active IP Right Cessation
- 1987-04-29 ES ES8701280A patent/ES2017805A6/es not_active Expired - Lifetime
- 1987-04-30 JP JP62104612A patent/JP2542210B2/ja not_active Expired - Lifetime
- 1987-04-30 FR FR878706196A patent/FR2598084B1/fr not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NO871759D0 (no)	1987-04-28
ES2017805A6 (es)	1991-03-01
FR2598084A1 (fr)	1987-11-06
JPS63107933A (ja)	1988-05-12
SE8701787L (sv)	1987-10-31
NO871759L (no)	1987-11-02
FR2598084B1 (fr)	1991-04-26
DK167735B1 (da)	1993-12-13
IT8767365A0 (it)	1987-04-29
IT1208416B (it)	1989-06-12
SE8701787D0 (sv)	1987-04-29
FI871852A0 (fi)	1987-04-28
DK218587A (da)	1987-10-31
JP2542210B2 (ja)	1996-10-09
SE503233C2 (sv)	1996-04-22
FI89457B (fi)	1993-06-30
DK218587D0 (da)	1987-04-29
FI871852L (fi)	1987-10-31
NO174085C (no)	1994-03-16
DE3714159C2 (de)	1996-09-19
NO174085B (no)	1993-12-06
DE3714159A1 (de)	1987-11-05

Legal Events

Date	Code	Title	Description
1993-06-01	BB	Publication of examined application
2004-08-31	FG	Patent granted	Owner name: CHUGAI SEIYAKU KABUSHIKI KAISHA
2007-05-08	MA	Patent expired

Publication	Publication Date	Title
FI94214B (fi)	1995-04-28	Menetelmä farmaseuttisen tabletin ja farmaseuttisen granulaatin valmistamiseksi
DE69100991T2 (de)	1994-05-05	Pharmazeutische formulierungen.
DE3783394T2 (de)	1993-05-06	Arzneizubereitung zur oralen anwendung.
DE69110969T2 (de)	1995-11-16	Verwendung von Triclosan zur Behandlung von Krankheiten des Gastrointestinaltraktes.
FI100219B (fi)	1997-10-31	Menetelmä farmaseuttisen granulaatin valmistamiseksi
DE3783386T2 (de)	1993-05-06	Arzneiformulierungen saeurelabiler substanzen zur oralen verwendung.
DE69625046T2 (de)	2003-04-10	Pharmazeutische zusammensetzung stabilisiert mit einem basischen medium
CA1040532A (en)	1978-10-17	Process for producing solid bismuth-containing pharmaceutical compositions
DE2845326C2 (de)	1985-05-23	Verwendung einer spezifischen mikrodispersen, amorphen, porösen Kieselsäure zur Herstellung von Digoxin enthaltenden Tabletten mit stark beschleunigter Wirkstoff-Freisetzung
CH662947A5 (de)	1987-11-13	Sich schnell aufloesende, pharmazeutische zubereitung sowie verfahren zu ihrer herstellung.
DE68902782T2 (de)	1993-04-01	Dispergierbare, cimetidin enthaltende tabletten.
US6291462B1 (en)	2001-09-18	Oral medicinal preparations with reproducible release of the active ingredient gatifloxacin or its pharmaceutically suitable salts or hydrates
DE69227773T2 (de)	1999-05-20	Tabletten mit hohem gehalt an colestipolhydrochlorid
FI89457C (fi)	1993-10-11	Foerfarande foer framstaellning av ett preparat som innehaoller ett aluminiumsalt av en sackarossulfatester
DE69111574T2 (de)	1996-01-18	Polycarbophil-Kalzium enthaltendes Arzneimittel.
DE69525649T2 (de)	2002-09-05	Lamotrigin haltiges arzneimittel
DE69011836T2 (de)	1995-03-09	Verfahren zur Hestellung von Tabletten, die sprühgetrocknetes Naproxen oder Naproxen Natriumsalz enthalten.
DE69712033T2 (de)	2002-08-22	Anionenaustauscherharze enthaltende tabletten
DE69002822T2 (de)	1993-12-23	Pharmazeutische Zubereitung zur oralen Verabreichung in flüssiger Form.
DE69904465T2 (de)	2003-10-02	Therapie von depressionen
DE68902764T2 (de)	1993-01-28	Antibakterielle zusammensetzung zur oralen verabreichung.
US4012498A (en)	1977-03-15	Sustained release tablet formulations
US5547943A (en)	1996-08-20	Sucralfate preparation
DE69524226T2 (de)	2002-06-27	Verfahren zum herstellen von fusidinsäuretabletten
US3155577A (en)	1964-11-03	Tasteless dioctylsulfosuccinate composition and method of making same