FI940904L - Oxazolidinedione derivatives, their preparation and use - Google Patents

Oxazolidinedione derivatives, their preparation and use Download PDF

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Publication number
FI940904L
FI940904L FI940904A FI940904A FI940904L FI 940904 L FI940904 L FI 940904L FI 940904 A FI940904 A FI 940904A FI 940904 A FI940904 A FI 940904A FI 940904 L FI940904 L FI 940904L
Authority
FI
Finland
Prior art keywords
preparation
oxazolidinedione derivatives
oxazolidinedione
derivatives
Prior art date
Application number
FI940904A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI940904A7 (en
FI940904A0 (en
Inventor
Takashi Sohda
Hitoshi Ideda
Yu Momose
Sachiko Imai
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FI940904A0 publication Critical patent/FI940904A0/en
Publication of FI940904A7 publication Critical patent/FI940904A7/en
Publication of FI940904L publication Critical patent/FI940904L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/44—Two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
FI940904A 1993-02-26 1994-02-25 Oxazolidinedione derivatives, their preparation and use FI940904L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3823693 1993-02-26
JP19730493 1993-08-09

Publications (3)

Publication Number Publication Date
FI940904A0 FI940904A0 (en) 1994-02-25
FI940904A7 FI940904A7 (en) 1994-11-29
FI940904L true FI940904L (en) 1994-11-29

Family

ID=26377445

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940904A FI940904L (en) 1993-02-26 1994-02-25 Oxazolidinedione derivatives, their preparation and use

Country Status (18)

Country Link
US (4) US5665748A (en)
EP (1) EP0612743B1 (en)
JP (2) JP3328720B2 (en)
KR (1) KR940019699A (en)
CN (1) CN1098411A (en)
AT (1) ATE157975T1 (en)
AU (1) AU673034B2 (en)
CA (1) CA2116387C (en)
DE (1) DE69405425T2 (en)
DK (1) DK0612743T3 (en)
ES (1) ES2108375T3 (en)
FI (1) FI940904L (en)
GR (1) GR3025342T3 (en)
HU (1) HUT70159A (en)
NO (1) NO305079B1 (en)
PH (1) PH31468A (en)
RU (1) RU2126797C1 (en)
TW (1) TW268952B (en)

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US5468762A (en) * 1994-05-18 1995-11-21 American Home Products Corporation Azolidinediones as antihyperglycemic agents
US5641796A (en) * 1994-11-01 1997-06-24 Eli Lilly And Company Oral hypoglycemic agents
TW403748B (en) * 1994-11-02 2000-09-01 Takeda Chemical Industries Ltd An oxazolidinedione derivative, its production and a pharmaceutical composition for lowering blood sugar and lipid in blood comprising the same
CA2171702A1 (en) * 1995-03-14 1996-09-15 Takashi Sohda Benzofuran compounds and their use
JPH09136877A (en) * 1995-06-16 1997-05-27 Takeda Chem Ind Ltd Heterocyclic compound, its production and use thereof
PT891340E (en) 1996-04-03 2003-03-31 Takeda Chemical Industries Ltd OXAZOLE DERIVATIVES ITS PREPARATION AND UTILIZATION
JPH09323930A (en) 1996-04-04 1997-12-16 Takeda Chem Ind Ltd Preventive and treating agent for cachexia
ZA973850B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
ZA973848B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US5919782A (en) * 1996-05-06 1999-07-06 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
FR2749583B1 (en) 1996-06-07 1998-08-21 Lipha NOVEL SUBSTITUTED THIAZOLIDINE -2,4- DIONE DERIVATIVES, PROCESSES FOR OBTAINING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
CZ298812B6 (en) * 1996-07-01 2008-02-13 Dr. Reddy's Laboratories Limited Azolidinedione derivatives, process of their preparation, pharmaceutical compositions in which the derivatives are comprised and their use in the treatment of diabetes mellitus and related diseases
US6372750B2 (en) 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
US6114526A (en) 1996-07-01 2000-09-05 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) * 1996-07-01 2006-09-05 Dr. Reddy's Laboratories, Limited Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6204277B1 (en) 1996-08-19 2001-03-20 Japan Tobacco Inc. Propionic acid derivatives and applications thereof
US6011036A (en) * 1997-04-15 2000-01-04 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic hypolipidemic antihypertensive properties process for their preparation and pharmaceutical compositions containing them
US6011031A (en) * 1997-05-30 2000-01-04 Dr. Reddy's Research Foundation Azolidinediones useful for the treatment of diabetes, dyslipidemia and hypertension: process for their preparation and pharmaceutical compositions containing them
US7045519B2 (en) 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
KR100581199B1 (en) 1998-06-19 2006-05-17 카이론 코포레이션 Inhibitors of Glycogen Synthase Kinase 3
CN1053186C (en) * 1998-07-09 2000-06-07 华东理工大学 Quinolinoxazole compound
JP2000044551A (en) * 1998-07-27 2000-02-15 Konica Corp Production of 3-substituted-3-oxo-2-(2,4-oxazolidinedion-3-yl) propionamide compound
AU6331199A (en) * 1998-09-30 2000-04-17 Roche Diagnostics Gmbh Oxazolidine derivatives for the treatment and prevention of metabolic bone disorders
US6121300A (en) * 1998-11-10 2000-09-19 Wagle; Dilip R. Reversing advanced glycosylation cross-links using heterocyclic-substituted thiazolium salts
PL197077B1 (en) * 1998-12-01 2008-02-29 Reddys Lab Inc Dr New pharmaceutical composition and the process for its preparation
ES2343104T3 (en) 1999-04-07 2010-07-23 Daiichi Sankyo Company, Limited AMINA DERIVATIVES
ES2277842T3 (en) 1999-06-18 2007-08-01 MERCK & CO., INC. DERIVATIVES OF ARILTIAZOLIDINDIONA AND ARILOXAZOLIDINDIONA.
DE60029446T2 (en) 1999-06-18 2007-02-08 Merck & Co., Inc. ARYLTHIAZOLIDEINDIONE AND ARYLOXAZOIDIDE DERIVATIVES
GB9914977D0 (en) 1999-06-25 1999-08-25 Glaxo Group Ltd Chemical compounds
JP4316787B2 (en) * 2000-01-11 2009-08-19 壽製薬株式会社 An ether or amide derivative, a process for producing the same, and a therapeutic agent for diabetes containing the same,
US7105551B2 (en) 2000-12-20 2006-09-12 Smithkline Beecham Corporation Thiazole derivatives for treating PPAR related disorders
EP1394154A4 (en) * 2001-03-23 2005-05-18 Takeda Pharmaceutical HETEROCYCLIC DERIVATIVE WITH FIVE MEMBERS OF ALKANOIC ACID
TW200300681A (en) * 2001-11-12 2003-06-16 Ono Pharmaceutical Co Carboxylic acid derivative compound and medicament containing same as active ingredient
AU2003203170A1 (en) * 2002-01-17 2003-07-30 Takeda Chemical Industries, Ltd. Nitrogenous heterocyclic compounds, process for preparation of the same and use thereof
TWI327462B (en) * 2002-01-18 2010-07-21 Sumitomo Chemical Co Condensed heterocyclic sulfonyl urea compound, a herbicide containing the same, and a method for weed control using the same
US7232828B2 (en) 2002-08-10 2007-06-19 Bethesda Pharmaceuticals, Inc. PPAR Ligands that do not cause fluid retention, edema or congestive heart failure
US6794401B2 (en) * 2003-01-17 2004-09-21 Bexel Pharmaceuticals, Inc. Amino acid phenoxy ethers
US7521465B2 (en) * 2003-01-17 2009-04-21 Bexel Pharmaceuticals, Inc. Diphenyl ether derivatives
US7781464B2 (en) * 2003-01-17 2010-08-24 Bexel Pharmaceuticals, Inc. Heterocyclic diphenyl ethers
CN1812977A (en) 2003-04-30 2006-08-02 药物研发有限责任公司 Substituted carboxylic acids
US7087576B2 (en) * 2003-10-07 2006-08-08 Bexel Pharmaceuticals, Inc. Dipeptide phenyl ethers
CN100451008C (en) * 2004-01-20 2009-01-14 默克公司 Antidiabetic oxazolidinediones and thiazolidinediones
TW200630327A (en) * 2004-10-28 2006-09-01 Inst For Pharm Discovery Inc Substituted phenylalkanoic acids
TW200932219A (en) * 2007-10-24 2009-08-01 Astellas Pharma Inc Oxadiazolidinedione compound
WO2021016043A1 (en) 2019-07-19 2021-01-28 Inari Agriculture, Inc. Improved homology dependent repair genome editing
WO2026008867A1 (en) * 2024-07-04 2026-01-08 Institut National de la Santé et de la Recherche Médicale Novel inhibitors of acsl4 and their use as medicines

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US4430337A (en) * 1982-06-23 1984-02-07 Pfizer Inc. Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity
US5232925A (en) * 1987-09-04 1993-08-03 Beecham Group P.L.C. Compounds
WO1989008650A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Thiazolidinedione hypoglycemic agents
WO1991007107A1 (en) * 1989-11-13 1991-05-30 Pfizer Inc. Oxazolidinedione hypoglycemic agents
US5143930A (en) * 1990-02-07 1992-09-01 Sankyo Company, Limited Thiazolidine derivatives with anti-diabetic activity, their preparation and their use
JP2991801B2 (en) * 1990-04-27 1999-12-20 三共株式会社 Benzylidene thiazolidine compound
US5037842A (en) 1990-06-05 1991-08-06 Pfizer Inc. Oxa- and thiazolidinedione hypoglycemic and hypocholesterolemic agents
GB9017218D0 (en) * 1990-08-06 1990-09-19 Beecham Group Plc Novel compounds
CA2106967C (en) * 1991-04-11 2003-12-09 Takashi Sohda Thiazolidinedione derivatives, production and use thereof
HUT70421A (en) * 1991-07-30 1995-10-30 Yamanouchi Pharma Co Ltd Novel bisoxazolidine derivatives pharmaceutical compositions containing them and process for preparing them
JPH05202042A (en) * 1992-01-24 1993-08-10 Sankyo Co Ltd Therapeutic agent for diabetic complication
HU220601B1 (en) * 1992-04-30 2002-03-28 Taiho Pharmaceutical Co. Ltd. Phenoxyalkyloxazolidine derivatives, process for their preparation and pharmaceutical compositions containing them
US5928152A (en) * 1994-08-05 1999-07-27 Acuson Corporation Method and apparatus for a baseband processor of a receive beamformer system

Also Published As

Publication number Publication date
HU9400578D0 (en) 1994-05-30
GR3025342T3 (en) 1998-02-27
CA2116387C (en) 2003-12-23
JPH07165735A (en) 1995-06-27
JP3328720B2 (en) 2002-09-30
AU5515894A (en) 1994-09-01
US6147099A (en) 2000-11-14
AU673034B2 (en) 1996-10-24
FI940904A7 (en) 1994-11-29
TW268952B (en) 1996-01-21
PH31468A (en) 1998-11-03
CN1098411A (en) 1995-02-08
DE69405425T2 (en) 1998-03-19
DK0612743T3 (en) 1998-04-20
EP0612743B1 (en) 1997-09-10
EP0612743A1 (en) 1994-08-31
ATE157975T1 (en) 1997-09-15
ES2108375T3 (en) 1997-12-16
HUT70159A (en) 1995-09-28
NO305079B1 (en) 1999-03-29
CA2116387A1 (en) 1994-08-27
KR940019699A (en) 1994-09-14
DE69405425D1 (en) 1997-10-16
NO940610D0 (en) 1994-02-23
RU2126797C1 (en) 1999-02-27
FI940904A0 (en) 1994-02-25
NO940610L (en) 1994-08-29
US6552058B1 (en) 2003-04-22
US5972970A (en) 1999-10-26
US5665748A (en) 1997-09-09
JP2000191651A (en) 2000-07-11

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