FI964914L - 2-amino-3-aroyylibentso/beta/tiofeenejä ja menetelmä niiden valmistamiseksi - Google Patents

2-amino-3-aroyylibentso/beta/tiofeenejä ja menetelmä niiden valmistamiseksi Download PDF

Info

Publication number
FI964914L
FI964914L FI964914A FI964914A FI964914L FI 964914 L FI964914 L FI 964914L FI 964914 A FI964914 A FI 964914A FI 964914 A FI964914 A FI 964914A FI 964914 L FI964914 L FI 964914L
Authority
FI
Finland
Prior art keywords
aroylbenzo
thiophenes
beta
amino
preparation
Prior art date
Application number
FI964914A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI964914A0 (fi
FI964914A7 (fi
Inventor
Alexander Glenn Godfrey
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI964914A0 publication Critical patent/FI964914A0/fi
Publication of FI964914L publication Critical patent/FI964914L/fi
Publication of FI964914A7 publication Critical patent/FI964914A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/66—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Oncology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Cephalosporin Compounds (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Thermal Insulation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
FI964914A 1994-06-10 1995-06-07 2-amino-3-aroyylibentso/beta/tiofeenejä ja menetelmä niiden valmistami seksi FI964914A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/257,859 US5466810A (en) 1994-06-10 1994-06-10 2-amino-3-aroyl-benzo[β]thiophenes and methods for preparing and using same to produce 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-(2-aminoethoxy)-benzoyl]benzo[β]thiophenes
PCT/US1995/007397 WO1995034557A1 (en) 1994-06-10 1995-06-07 2-AMINO-3-AROYL-BENZO[β]THIOPHENES AND METHOD OF MAKING THE SAME

Publications (3)

Publication Number Publication Date
FI964914A0 FI964914A0 (fi) 1996-12-09
FI964914L true FI964914L (fi) 1996-12-09
FI964914A7 FI964914A7 (fi) 1996-12-09

Family

ID=22978079

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964914A FI964914A7 (fi) 1994-06-10 1995-06-07 2-amino-3-aroyylibentso/beta/tiofeenejä ja menetelmä niiden valmistami seksi

Country Status (14)

Country Link
US (3) US5466810A (da)
EP (1) EP0765321B1 (da)
JP (1) JPH10502057A (da)
AT (1) ATE200671T1 (da)
AU (1) AU2702995A (da)
BR (1) BR9507956A (da)
CA (1) CA2192097A1 (da)
DE (1) DE69520738T2 (da)
DK (1) DK0765321T3 (da)
ES (1) ES2155891T3 (da)
FI (1) FI964914A7 (da)
GR (1) GR3036028T3 (da)
PT (1) PT765321E (da)
WO (1) WO1995034557A1 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5770609A (en) 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US5595722A (en) 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
ATE377418T1 (de) 1995-06-07 2007-11-15 Poniard Pharmaceuticals Inc Vorbeugung und behandlung von kardiovaskulären beschwerden mit tamoxifen-analogen
US5606075A (en) * 1995-06-07 1997-02-25 Eli Lilly And Company Process for the synthesis of benzo[b]thiophenes
CA2207141A1 (en) * 1996-07-15 1998-01-15 David Thompson Berg Benzothiophene compounds, and uses and formulations thereof
US5792798A (en) * 1996-07-29 1998-08-11 Eli Lilly And Company Method for inhibiting plasminogen activator inhibitor 1
ZA9710262B (en) * 1996-11-19 1999-05-13 Lilly Co Eli Process for the synthesis of benzothiophenes
US6117911A (en) * 1997-04-11 2000-09-12 Neorx Corporation Compounds and therapies for the prevention of vascular and non-vascular pathologies
ES2246234T3 (es) 1999-05-04 2006-02-16 Strakan International Limited Glicosidos de androgenos y actividad androgenica de los mismos.
US6232260B1 (en) 1999-10-14 2001-05-15 Equistar Chemicals, L.P. Single-site catalysts for olefin polymerization
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US7144885B2 (en) * 2002-02-22 2006-12-05 Bayer Pharmaceuticals Corporation Fused tricyclic heterocycles useful for treating hyper-proliferative disorders
CN1639146A (zh) * 2002-02-22 2005-07-13 拜尔药品公司 用于治疗过度增生疾病的稠合三环杂环
EP2316468A1 (en) 2002-02-22 2011-05-04 Shire LLC Delivery system and methods for protecting and administering dextroamphetamine
US20100125073A1 (en) * 2006-09-01 2010-05-20 Olaf Weber Benzofuran and benzothiophene derivatives useful in the treatment of cancers of the central nervous system
WO2011109679A2 (en) * 2010-03-05 2011-09-09 Amira Pharmaceuticals, Inc. Inhibitors of 5-lipoxygenase
CN102653520A (zh) * 2012-04-10 2012-09-05 苏州大学 一种2-羟基-2-芳基硫代乙酰胺的制备方法
WO2018060224A1 (en) * 2016-09-27 2018-04-05 Dsm Ip Assets B.V. Transparent drawn article

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US4380635A (en) * 1981-04-03 1983-04-19 Eli Lilly And Company Synthesis of acylated benzothiophenes
US5420349A (en) * 1994-06-10 1995-05-30 Eli Lilly And Company 2-amino-3-aroyl-benzo[β]thiophenes and methods for preparing and using same to produce 6-hydroxy-2-(4-hydroxyphenyl)-3-]benzo[4-(2-aminoethoxy)-benzoyl[β]thiophenes

Also Published As

Publication number Publication date
US5466810A (en) 1995-11-14
EP0765321B1 (en) 2001-04-18
DK0765321T3 (da) 2001-05-07
ATE200671T1 (de) 2001-05-15
ES2155891T3 (es) 2001-06-01
FI964914A0 (fi) 1996-12-09
CA2192097A1 (en) 1995-12-21
AU2702995A (en) 1996-01-05
FI964914A7 (fi) 1996-12-09
GR3036028T3 (en) 2001-09-28
PT765321E (pt) 2001-07-31
EP0765321A4 (da) 1997-05-02
DE69520738D1 (de) 2001-05-23
US5554755A (en) 1996-09-10
EP0765321A1 (en) 1997-04-02
WO1995034557A1 (en) 1995-12-21
US5792870A (en) 1998-08-11
BR9507956A (pt) 1997-08-12
DE69520738T2 (de) 2001-09-13
JPH10502057A (ja) 1998-02-24

Similar Documents

Publication Publication Date Title
FI964914L (fi) 2-amino-3-aroyylibentso/beta/tiofeenejä ja menetelmä niiden valmistamiseksi
FI962954A7 (fi) Substituoidut 3-arylideeni-7-atsaoksindoliyhdisteet ja menetelmä niiden valmistamiseksi
FI960751A7 (fi) Substituoidut atsaindolylideeniyhdisteet ja menetelmä niiden valmistamiseksi
FI914723A7 (fi) 17b-substituoituja 4-atsa-5a-androstan-3-oni-johdannaisia ja menetelmä niiden valmistamiseksi
FI973426L (fi) Bentsopyraania sisältävät yhdisteet ja menetelmä niiden valmistamiseksi
EE9900014A (et) Erütromütsiinid ja nende valmistamise protsess
FI941137L (fi) 2-debentsoyyli-2-asyylitaksolijohdannaisia ja menetelmiä niiden valmistamiseksi
EE03231B1 (et) Tetratsüklilised derivaadid, nende valmistamismeetod ja kasutamine
FI972309A0 (fi) 2-heterosyklyylioksi- ja tiometyyli-1,2,5-tiaditsolidin-3-oni-1,1-dioksideja, niitä sisältäviä koostumuksia ja menetelmä niiden valmistamiseksi
FI953981A7 (fi) 2-Bentsyyli-polysykliset guaniinijohdannaiset ja menetelmä niiden valmistamiseksi
FI962917A7 (fi) Mikrokapselit, menetelmä niiden valmistamiseksi, ja niiden käyttö
FI953919A7 (fi) Pyrrolydeenimetyylijohdannaiset ja menetelmä niiden valmistamiseksi
FI964102L (fi) Menetelmä fenolin ja fenolijohdannaisten valmistamiseksi
FI971268A7 (fi) Menetelmä 1,3-alkaanidiolien ja 3-hydroksialdehydien valmistamiseksi
FI944713L (fi) 4-difenyylimetyylipiperidiinijohdannaisia ja menetelmä niiden valmistamiseksi
FI942546L (fi) Menetelmä hienojakoisten ja muunnettujen tärkkelyksien valmistamiseksi
FI971138A7 (fi) Keraamisia eristeitä ja menetelmiä niiden muodostamiseksi
FI960316L (fi) Oksatiolaanit, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
FI942298A0 (fi) Menetelmä ja sovitelma tilaelementtien siirtämiseksi
FI955123A0 (fi) Kolestyramiinia sisältävä koostumus ja menetelmä tämän valmistamiseksi
FI973434L (fi) Aminotetralonijohdannaisia ja menetelmä niiden valmistamiseksi
FI905173A7 (fi) Diatsabisykloamiiniyhdisteet ja menetelmä niiden valmistamiseksi
FI944842L (fi) Fluoratut 4-aminoandrostadienonijohdannaiset ja menetelmä niiden valmistamiseksi
FI932863A7 (fi) Menetelmä uusien tienotiatsiinijohdosten valmistamiseksi ja niiden käyttö
FI981359L (fi) Uudet tiomarinolin johdannaiset ja menetelmät niiden valmistamiseksi