FI971177L - Bisyklisiä karboksiamideja 5-HT1A-antagonisteina - Google Patents

Bisyklisiä karboksiamideja 5-HT1A-antagonisteina Download PDF

Info

Publication number: FI971177L
Authority: FI; Finland
Prior art keywords: ht1a antagonists; carboxamides; bicyclic; bicyclic carboxamides; ht1a
Prior art date: 1994-09-21

Application number

FI971177A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI971177A0 (fi

FI971177A7 (fi

Inventor

Ian Anthony Cliffe

Howard Langham Mansell

Terence James Ward

James Albert Nelson

Uresh Shantilal Shah

Mira Ana Kanzelberger

Original Assignee

Wyeth John & Brother Ltd

American Home Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-21

Filing date

1995-08-23

Publication date

1997-05-20

1995-08-23 Application filed by Wyeth John & Brother Ltd, American Home Prod filed Critical Wyeth John & Brother Ltd

1997-03-20 Publication of FI971177A0 publication Critical patent/FI971177A0/fi

1997-05-20 Publication of FI971177A7 publication Critical patent/FI971177A7/fi

1997-05-20 Publication of FI971177L publication Critical patent/FI971177L/fi

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Epidemiology (AREA)
Heart & Thoracic Surgery (AREA)
Anesthesiology (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

FI971177A 1994-09-21 1995-08-23 Bisyklisiä karboksiamideja 5-HT1A-antagonisteina FI971177L (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB9419024A GB9419024D0 (en)	1994-09-21	1994-09-21	Bicyclic carboxamides
PCT/GB1995/002001 WO1996009302A1 (fr)	1994-09-21	1995-08-23	Carboxamides bicycliques en tant qu'antagonistes de 5-ht¿1a?

Publications (3)

Publication Number	Publication Date
FI971177A0 FI971177A0 (fi)	1997-03-20
FI971177A7 FI971177A7 (fi)	1997-05-20
FI971177L true FI971177L (fi)	1997-05-20

Family

ID=10761683

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI971177A FI971177L (fi)	1994-09-21	1995-08-23	Bisyklisiä karboksiamideja 5-HT1A-antagonisteina

Country Status (22)

Country	Link
US (1)	US5610154A (fr)
EP (1)	EP0782574B1 (fr)
JP (1)	JPH10505853A (fr)
KR (1)	KR970706280A (fr)
CN (1)	CN1043764C (fr)
AT (1)	ATE215083T1 (fr)
AU (1)	AU692917B2 (fr)
BR (1)	BR9508979A (fr)
CA (1)	CA2200443A1 (fr)
DE (1)	DE69526097D1 (fr)
DK (1)	DK0782574T3 (fr)
ES (1)	ES2170802T3 (fr)
FI (1)	FI971177L (fr)
GB (1)	GB9419024D0 (fr)
HU (1)	HUT77940A (fr)
IL (1)	IL115085A (fr)
MX (1)	MX9702089A (fr)
NZ (1)	NZ291855A (fr)
PT (1)	PT782574E (fr)
TW (1)	TW424092B (fr)
WO (1)	WO1996009302A1 (fr)
ZA (1)	ZA957449B (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5607936A (en) *	1994-09-30	1997-03-04	Merck & Co., Inc.	Substituted aryl piperazines as neurokinin antagonists
FR2756283A1 (fr) *	1996-11-27	1998-05-29	Pf Medicament	Amines aromatiques d'arylpiperazines, leur preparation et leurs applications comme medicaments
US5919802A (en) *	1997-12-05	1999-07-06	Princeton University	Methods of preventing and/or treating temporal lobe epilepsy
ITMI20021327A1 (it) *	2002-06-14	2003-12-15	Recordati Chem Pharm	Nuove ossialchilpiperazine
US20040153119A1 (en) *	2003-01-30	2004-08-05	Kusleika Richard S.	Embolic filters with a distal loop or no loop

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3422092A (en) *	1966-02-18	1969-01-14	Upjohn Co	2 - carbamoyl - 2-azabicyclo(2.2.2)octanes,and 3 - carbamoyl - 3 - azabicyclo(3.2.2) nonanes
KR0173310B1 (ko) *	1989-04-22	1999-02-01	폴 에이 리쳐	피페라진 유도체
GB9022820D0 (en) *	1990-10-19	1990-12-05	Wyeth John & Brother Ltd	Piperazine derivatives
GB9125900D0 (en) *	1991-12-05	1992-02-05	Wyeth John & Brother Ltd	Piperazine derivatives
GB9300195D0 (en) *	1993-01-06	1993-03-03	Wyeth John & Brother Ltd	Piperazine derivatives

1994
- 1994-09-21 GB GB9419024A patent/GB9419024D0/en active Pending
1995
- 1995-05-24 US US08/448,962 patent/US5610154A/en not_active Expired - Lifetime
- 1995-08-23 NZ NZ291855A patent/NZ291855A/xx unknown
- 1995-08-23 PT PT95929941T patent/PT782574E/pt unknown
- 1995-08-23 AU AU33501/95A patent/AU692917B2/en not_active Ceased
- 1995-08-23 DE DE69526097T patent/DE69526097D1/de not_active Expired - Lifetime
- 1995-08-23 CA CA002200443A patent/CA2200443A1/fr not_active Abandoned
- 1995-08-23 EP EP95929941A patent/EP0782574B1/fr not_active Expired - Lifetime
- 1995-08-23 JP JP8510658A patent/JPH10505853A/ja not_active Ceased
- 1995-08-23 CN CN95195207A patent/CN1043764C/zh not_active Expired - Fee Related
- 1995-08-23 FI FI971177A patent/FI971177L/fi unknown
- 1995-08-23 AT AT95929941T patent/ATE215083T1/de not_active IP Right Cessation
- 1995-08-23 HU HU9800408A patent/HUT77940A/hu unknown
- 1995-08-23 DK DK95929941T patent/DK0782574T3/da active
- 1995-08-23 MX MX9702089A patent/MX9702089A/es unknown
- 1995-08-23 WO PCT/GB1995/002001 patent/WO1996009302A1/fr not_active Ceased
- 1995-08-23 ES ES95929941T patent/ES2170802T3/es not_active Expired - Lifetime
- 1995-08-23 BR BR9508979A patent/BR9508979A/pt not_active Application Discontinuation
- 1995-08-28 IL IL11508595A patent/IL115085A/xx not_active IP Right Cessation
- 1995-09-05 ZA ZA957449A patent/ZA957449B/xx unknown
- 1995-09-19 TW TW084109809A patent/TW424092B/zh not_active IP Right Cessation
1997
- 1997-03-19 KR KR1019970701764A patent/KR970706280A/ko not_active Ceased

Also Published As

Publication number	Publication date
AU3350195A (en)	1996-04-09
WO1996009302A1 (fr)	1996-03-28
CA2200443A1 (fr)	1996-03-28
ZA957449B (en)	1997-03-05
FI971177A0 (fi)	1997-03-20
BR9508979A (pt)	1997-10-28
US5610154A (en)	1997-03-11
TW424092B (en)	2001-03-01
MX9702089A (es)	1997-06-28
AU692917B2 (en)	1998-06-18
GB9419024D0 (en)	1994-11-09
ES2170802T3 (es)	2002-08-16
NZ291855A (en)	1999-08-30
ATE215083T1 (de)	2002-04-15
EP0782574B1 (fr)	2002-03-27
IL115085A0 (en)	1995-12-08
FI971177A7 (fi)	1997-05-20
DE69526097D1 (de)	2002-05-02
KR970706280A (ko)	1997-11-03
JPH10505853A (ja)	1998-06-09
HUT77940A (hu)	1998-12-28
PT782574E (pt)	2002-08-30
DK0782574T3 (da)	2002-05-06
EP0782574A1 (fr)	1997-07-09
CN1043764C (zh)	1999-06-23
IL115085A (en)	1999-06-20
CN1158615A (zh)	1997-09-03

Publication	Publication Date	Title
DK0738150T3 (da)	2003-08-25	Bicykliske fibrinogene antagonister
NO972526D0 (no)	1997-06-03	Tachykininantagonister
EE9600186A (et)	1997-08-15	Neurokiniini (tahhüülkiniini) antagonistid
FI20040657A7 (fi)	2004-05-10	Kortikotropiinia vapauttavan tekijän antagonisteja
FI972194L (fi)	1997-05-22	Uusia bentsyylipyrimidiinejä
DE69533930D1 (de)	2005-02-17	Zahnbürste
FI971431L (fi)	1997-04-04	Hammasharja
DE59503597D1 (de)	1998-10-22	Zahnbürste
FI964815L (fi)	1996-12-02	Piperatsiinijohdoksia 5-HT1A antagonisteina
FI960727L (fi)	1996-02-16	Neurokiniiniantagonisteina käyttökelpoiset heterosyklit
FI954991A0 (fi)	1995-10-19	Bisyklisiä tetrahydropyrazolopyridiinejä
FI960516L (fi)	1996-08-07	Substituoituja bifenyylisulfonamidiendoteliiniantagonisteja
FI953710L (fi)	1996-02-05	Uusia pyrrolokarbatsoleja
ID22838A (id)	1999-12-09	Oksazolidina sebagai antagonis 5-ht2a
PT964867E (pt)	2005-07-29	Antagonistas da taquicinima
FI971177L (fi)	1997-05-20	Bisyklisiä karboksiamideja 5-HT1A-antagonisteina
FI963400L (fi)	1996-08-30	Bisykliset karbamaatit leukotrieeni D4 antagonisteina
KR960000268U (ko)	1996-01-17	치 솔
KR970702876A (ko)	1997-06-10	뉴로키닌 길항제(Neurokinine (tachykinine) antagonists)
KR950027351U (ko)	1995-10-18	반목 항타장치
DE59503458D1 (de)	1998-10-08	Balkon
KR950024320U (ko)	1995-09-13	치솔
KR950026481U (ko)	1995-10-16	칫솔
SI0782574T1 (en)	2002-06-30	Bicyclic carboxamides as 5-ht1a receptors ligands
SE9402421D0 (sv)	1994-07-08	New use