FI971777L - Katepsiini O2-proteaasi - Google Patents

Katepsiini O2-proteaasi Download PDF

Info

Publication number
FI971777L
FI971777L FI971777A FI971777A FI971777L FI 971777 L FI971777 L FI 971777L FI 971777 A FI971777 A FI 971777A FI 971777 A FI971777 A FI 971777A FI 971777 L FI971777 L FI 971777L
Authority
FI
Finland
Prior art keywords
cathepsin
protease
Prior art date
Application number
FI971777A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI971777A0 (fi
FI971777A7 (fi
Inventor
Dieter Broemme
Kathleen Okamoto
Original Assignee
Arris Pharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26987129&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI971777(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/330,121 external-priority patent/US5736357A/en
Application filed by Arris Pharm Corp filed Critical Arris Pharm Corp
Publication of FI971777L publication Critical patent/FI971777L/fi
Publication of FI971777A0 publication Critical patent/FI971777A0/fi
Publication of FI971777A7 publication Critical patent/FI971777A7/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472Cysteine endopeptidases (3.4.22)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI971777A 1994-10-27 1995-10-26 Katepsiini O2-proteaasi FI971777A7 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/330,121 US5736357A (en) 1994-10-27 1994-10-27 Cathespin O protease
US08/536,861 US6544767B1 (en) 1994-10-27 1995-10-02 Cathespin O2 protease
PCT/US1995/013820 WO1996013523A1 (en) 1994-10-27 1995-10-26 Cathepsin o2 protease

Publications (3)

Publication Number Publication Date
FI971777L true FI971777L (fi) 1997-04-25
FI971777A0 FI971777A0 (fi) 1997-04-25
FI971777A7 FI971777A7 (fi) 1997-04-25

Family

ID=26987129

Family Applications (1)

Application Number Title Priority Date Filing Date
FI971777A FI971777A7 (fi) 1994-10-27 1995-10-26 Katepsiini O2-proteaasi

Country Status (15)

Country Link
US (2) US6544767B1 (de)
EP (1) EP0783527B1 (de)
JP (1) JP3670666B2 (de)
KR (1) KR100473219B1 (de)
CN (1) CN1148382C (de)
AT (1) ATE317441T1 (de)
AU (1) AU711810B2 (de)
CA (1) CA2203765C (de)
DE (1) DE69534778T2 (de)
ES (1) ES2256849T3 (de)
FI (1) FI971777A7 (de)
HU (1) HU220960B1 (de)
NO (1) NO971875L (de)
NZ (1) NZ296003A (de)
WO (1) WO1996013523A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403304B1 (en) 1993-04-06 2002-06-11 Forsyth Dental Infirmary For Children Human osteoclast-specific and -related DNA sequences
US5501969A (en) 1994-03-08 1996-03-26 Human Genome Sciences, Inc. Human osteoclast-derived cathepsin
SK56798A3 (en) * 1995-10-30 1998-12-02 Smithkline Beecham Corp Protease inhibitors, pharmaceutical composition containing them and their use
US6586466B2 (en) 1995-10-30 2003-07-01 Smithkline Beecham Corporation Carbohydrazide-protease inhibitors
HUP9802488A3 (en) 1995-10-30 2001-10-29 Smithkline Beecham Corp Method of inhibiting cathepsin k
EP0812916A3 (de) * 1996-06-14 1998-12-09 Smithkline Beecham Corporation Cathepsin K Gen
AU3802297A (en) * 1996-07-03 1998-01-21 Novadx, Inc. Method for detecting degenerative bone disease
GB9701888D0 (en) * 1997-01-30 1997-03-19 Ciba Geigy Ag Novel methods
US5948669A (en) * 1997-02-26 1999-09-07 Smithkline Beecham Corporation Rat cathepsin K polynucleotide and polypeptide sequence
US20030144175A1 (en) 1998-12-23 2003-07-31 Smithkline Beecham Corporation Protease inhibitors
US6346373B1 (en) * 1999-05-05 2002-02-12 Merck Frosst Canada & Co., Whole cell assay for cathepsin K activity
AU6199100A (en) * 1999-06-25 2001-01-31 Hybritech Incorporated Cloning and expressing of human cathepsin k in mammalian cells
JP2003513971A (ja) 1999-11-10 2003-04-15 スミスクライン・ビーチャム・コーポレイション プロテア−ゼ阻害剤
EP1229914A4 (de) 1999-11-10 2004-06-23 Smithkline Beecham Corp Proteasehemmer
US6583137B1 (en) 1999-11-10 2003-06-24 Smithkline Beecham Corporation Protease inhibitors
CA2397194C (en) 2000-01-20 2011-05-17 Mark E. Duggan Alpha v integrin receptor antagonists
KR20020082896A (ko) 2000-03-21 2002-10-31 스미스클라인 비참 코포레이션 프로테아제 억제제
AU2002239753A1 (en) * 2000-10-18 2002-05-21 Incyte Genomics, Inc. Proteases
CN100408681C (zh) * 2002-06-17 2008-08-06 株式会社日冷 来源于粉红色虾的新型组织蛋白酶l样半胱氨酸蛋白酶
AU2003256305A1 (en) * 2002-06-24 2004-01-06 Axys Pharmaceuticals, Inc. Peptidic compounds as cysteine protease inhibitors
TW200510436A (en) * 2003-07-21 2005-03-16 Novartis Ag Combinations of a cathepsin k inhibitor and a bisphosphonate in the treatment of bone metastasis, tumor growth and tumor-induced bone loss
AU2004266740B2 (en) 2003-08-21 2010-08-26 Merck Frosst Canada Ltd Cathepsin cysteine protease inhibitors
US20070015234A1 (en) * 2003-09-23 2007-01-18 Sylvie Desmarais Whole cell assay for inhibitors of cathepsin k
WO2005093421A1 (de) * 2004-03-10 2005-10-06 Biovendor Laboratory Medicine, Inc. Enzymimmunoassay zur bestimmung von cathepsin k
US7029902B2 (en) * 2004-03-26 2006-04-18 Applera Corporation Isolated monkey cathepsin S proteins, nucleic acid molecules encoding monkey cathepsin S proteins, and uses thereof
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
AU2013202011C1 (en) * 2008-03-06 2015-10-01 Halozyme, Inc. In vivo temporal control of activatable matrix-degrading enzymes
TWI395593B (zh) 2008-03-06 2013-05-11 Halozyme Inc 可活化的基質降解酵素之活體內暫時性控制
US8901144B2 (en) 2013-02-07 2014-12-02 Scifluor Life Sciences, Llc Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives
HRP20171873T1 (hr) 2013-02-07 2018-02-23 Scifluor Life Sciences, Inc Fluorinirani antagonisti integrina
SG11201609050UA (en) 2014-05-30 2016-12-29 Pfizer Carbonitrile derivatives as selective androgen receptor modulators
KR102647026B1 (ko) 2015-02-19 2024-03-12 사이플루어 라이프 사이언시즈, 인크 플루오르화 테트라히드로나프티리디닐 노난산 유도체 및 이의 용도
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5501969A (en) 1994-03-08 1996-03-26 Human Genome Sciences, Inc. Human osteoclast-derived cathepsin
AU6333296A (en) 1996-06-14 1998-01-07 Human Genome Sciences, Inc. Cathepsin k gene

Also Published As

Publication number Publication date
NO971875D0 (no) 1997-04-23
ES2256849T3 (es) 2006-07-16
KR100473219B1 (ko) 2005-05-16
US20030175937A1 (en) 2003-09-18
FI971777A0 (fi) 1997-04-25
DE69534778T2 (de) 2006-08-17
CN1170415A (zh) 1998-01-14
EP0783527A1 (de) 1997-07-16
AU3968895A (en) 1996-05-23
AU711810B2 (en) 1999-10-21
HUT77049A (hu) 1998-03-02
NO971875L (no) 1997-06-12
WO1996013523A1 (en) 1996-05-09
DE69534778D1 (en) 2006-04-20
FI971777A7 (fi) 1997-04-25
JPH10512740A (ja) 1998-12-08
KR970707153A (ko) 1997-12-01
CN1148382C (zh) 2004-05-05
EP0783527A4 (de) 1998-12-02
ATE317441T1 (de) 2006-02-15
EP0783527B1 (de) 2006-02-08
CA2203765C (en) 2002-04-23
NZ296003A (en) 1999-10-28
CA2203765A1 (en) 1996-05-09
HU220960B1 (hu) 2002-07-29
JP3670666B2 (ja) 2005-07-13
US6544767B1 (en) 2003-04-08

Similar Documents

Publication Publication Date Title
FI971777L (fi) Katepsiini O2-proteaasi
KR970701725A (ko) 사람 파골세포 유래 카텝신(Human osteoclast-derived cathepsin)
FI954647L (fi) Proteaasimuunnokset
FI944033A7 (fi) Uusia proteaaseja
DK0778880T3 (da) Forbedret proteolytisk enzymrensemiddel
ID18001A (id) Penghambat-penghambat protease
NO944558L (no) Trykkveksler
FI951462A7 (fi) Paine-erokytkin
DK0979240T3 (da) Serinproteaseinhibitor
DE69535069D1 (de) Vermittlungseinrichtung
FI961350A7 (fi) Hapteenimerkityt peptidit
FI961097L (fi) Hapettumisenkestäviä proteaaseja
FI945163L (fi) Sieniproteaasi
FI970168A0 (fi) Peptidejä
FI964363L (fi) Peptidejä
DE69534544D1 (de) Vermittlungseinrichtung
DE69704741D1 (de) Schwimmflosse
FI940647A0 (fi) Parannetut erittäin alkaliset proteaasit
MA23665A1 (fr) Matllas gonflable
LV10836A (lv) Gofreta asinsvadu proteze
DK29795A (da) Trykafbryder
SE9400770D0 (sv) Integrerade knappar
KR960004318U (ko) 소형화한 예금통장
KR950023915U (ko) 플로우 스위치
KR960023689U (ko) 유로 전환밸브

Legal Events

Date Code Title Description
FD Application lapsed