FI971777L - Katepsiini O2-proteaasi - Google Patents
Katepsiini O2-proteaasi Download PDFInfo
- Publication number
- FI971777L FI971777L FI971777A FI971777A FI971777L FI 971777 L FI971777 L FI 971777L FI 971777 A FI971777 A FI 971777A FI 971777 A FI971777 A FI 971777A FI 971777 L FI971777 L FI 971777L
- Authority
- FI
- Finland
- Prior art keywords
- cathepsin
- protease
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6472—Cysteine endopeptidases (3.4.22)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/330,121 US5736357A (en) | 1994-10-27 | 1994-10-27 | Cathespin O protease |
| US08/536,861 US6544767B1 (en) | 1994-10-27 | 1995-10-02 | Cathespin O2 protease |
| PCT/US1995/013820 WO1996013523A1 (en) | 1994-10-27 | 1995-10-26 | Cathepsin o2 protease |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI971777L true FI971777L (fi) | 1997-04-25 |
| FI971777A0 FI971777A0 (fi) | 1997-04-25 |
| FI971777A7 FI971777A7 (fi) | 1997-04-25 |
Family
ID=26987129
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI971777A FI971777A7 (fi) | 1994-10-27 | 1995-10-26 | Katepsiini O2-proteaasi |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US6544767B1 (de) |
| EP (1) | EP0783527B1 (de) |
| JP (1) | JP3670666B2 (de) |
| KR (1) | KR100473219B1 (de) |
| CN (1) | CN1148382C (de) |
| AT (1) | ATE317441T1 (de) |
| AU (1) | AU711810B2 (de) |
| CA (1) | CA2203765C (de) |
| DE (1) | DE69534778T2 (de) |
| ES (1) | ES2256849T3 (de) |
| FI (1) | FI971777A7 (de) |
| HU (1) | HU220960B1 (de) |
| NO (1) | NO971875L (de) |
| NZ (1) | NZ296003A (de) |
| WO (1) | WO1996013523A1 (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6403304B1 (en) | 1993-04-06 | 2002-06-11 | Forsyth Dental Infirmary For Children | Human osteoclast-specific and -related DNA sequences |
| US5501969A (en) | 1994-03-08 | 1996-03-26 | Human Genome Sciences, Inc. | Human osteoclast-derived cathepsin |
| SK56798A3 (en) * | 1995-10-30 | 1998-12-02 | Smithkline Beecham Corp | Protease inhibitors, pharmaceutical composition containing them and their use |
| US6586466B2 (en) | 1995-10-30 | 2003-07-01 | Smithkline Beecham Corporation | Carbohydrazide-protease inhibitors |
| HUP9802488A3 (en) | 1995-10-30 | 2001-10-29 | Smithkline Beecham Corp | Method of inhibiting cathepsin k |
| EP0812916A3 (de) * | 1996-06-14 | 1998-12-09 | Smithkline Beecham Corporation | Cathepsin K Gen |
| AU3802297A (en) * | 1996-07-03 | 1998-01-21 | Novadx, Inc. | Method for detecting degenerative bone disease |
| GB9701888D0 (en) * | 1997-01-30 | 1997-03-19 | Ciba Geigy Ag | Novel methods |
| US5948669A (en) * | 1997-02-26 | 1999-09-07 | Smithkline Beecham Corporation | Rat cathepsin K polynucleotide and polypeptide sequence |
| US20030144175A1 (en) | 1998-12-23 | 2003-07-31 | Smithkline Beecham Corporation | Protease inhibitors |
| US6346373B1 (en) * | 1999-05-05 | 2002-02-12 | Merck Frosst Canada & Co., | Whole cell assay for cathepsin K activity |
| AU6199100A (en) * | 1999-06-25 | 2001-01-31 | Hybritech Incorporated | Cloning and expressing of human cathepsin k in mammalian cells |
| JP2003513971A (ja) | 1999-11-10 | 2003-04-15 | スミスクライン・ビーチャム・コーポレイション | プロテア−ゼ阻害剤 |
| EP1229914A4 (de) | 1999-11-10 | 2004-06-23 | Smithkline Beecham Corp | Proteasehemmer |
| US6583137B1 (en) | 1999-11-10 | 2003-06-24 | Smithkline Beecham Corporation | Protease inhibitors |
| CA2397194C (en) | 2000-01-20 | 2011-05-17 | Mark E. Duggan | Alpha v integrin receptor antagonists |
| KR20020082896A (ko) | 2000-03-21 | 2002-10-31 | 스미스클라인 비참 코포레이션 | 프로테아제 억제제 |
| AU2002239753A1 (en) * | 2000-10-18 | 2002-05-21 | Incyte Genomics, Inc. | Proteases |
| CN100408681C (zh) * | 2002-06-17 | 2008-08-06 | 株式会社日冷 | 来源于粉红色虾的新型组织蛋白酶l样半胱氨酸蛋白酶 |
| AU2003256305A1 (en) * | 2002-06-24 | 2004-01-06 | Axys Pharmaceuticals, Inc. | Peptidic compounds as cysteine protease inhibitors |
| TW200510436A (en) * | 2003-07-21 | 2005-03-16 | Novartis Ag | Combinations of a cathepsin k inhibitor and a bisphosphonate in the treatment of bone metastasis, tumor growth and tumor-induced bone loss |
| AU2004266740B2 (en) | 2003-08-21 | 2010-08-26 | Merck Frosst Canada Ltd | Cathepsin cysteine protease inhibitors |
| US20070015234A1 (en) * | 2003-09-23 | 2007-01-18 | Sylvie Desmarais | Whole cell assay for inhibitors of cathepsin k |
| WO2005093421A1 (de) * | 2004-03-10 | 2005-10-06 | Biovendor Laboratory Medicine, Inc. | Enzymimmunoassay zur bestimmung von cathepsin k |
| US7029902B2 (en) * | 2004-03-26 | 2006-04-18 | Applera Corporation | Isolated monkey cathepsin S proteins, nucleic acid molecules encoding monkey cathepsin S proteins, and uses thereof |
| UA87854C2 (en) | 2004-06-07 | 2009-08-25 | Мерк Энд Ко., Инк. | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators |
| AU2013202011C1 (en) * | 2008-03-06 | 2015-10-01 | Halozyme, Inc. | In vivo temporal control of activatable matrix-degrading enzymes |
| TWI395593B (zh) | 2008-03-06 | 2013-05-11 | Halozyme Inc | 可活化的基質降解酵素之活體內暫時性控制 |
| US8901144B2 (en) | 2013-02-07 | 2014-12-02 | Scifluor Life Sciences, Llc | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives |
| HRP20171873T1 (hr) | 2013-02-07 | 2018-02-23 | Scifluor Life Sciences, Inc | Fluorinirani antagonisti integrina |
| SG11201609050UA (en) | 2014-05-30 | 2016-12-29 | Pfizer | Carbonitrile derivatives as selective androgen receptor modulators |
| KR102647026B1 (ko) | 2015-02-19 | 2024-03-12 | 사이플루어 라이프 사이언시즈, 인크 | 플루오르화 테트라히드로나프티리디닐 노난산 유도체 및 이의 용도 |
| WO2023275715A1 (en) | 2021-06-30 | 2023-01-05 | Pfizer Inc. | Metabolites of selective androgen receptor modulators |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5501969A (en) | 1994-03-08 | 1996-03-26 | Human Genome Sciences, Inc. | Human osteoclast-derived cathepsin |
| AU6333296A (en) | 1996-06-14 | 1998-01-07 | Human Genome Sciences, Inc. | Cathepsin k gene |
-
1995
- 1995-10-02 US US08/536,861 patent/US6544767B1/en not_active Expired - Fee Related
- 1995-10-26 AU AU39688/95A patent/AU711810B2/en not_active Ceased
- 1995-10-26 JP JP51472296A patent/JP3670666B2/ja not_active Expired - Fee Related
- 1995-10-26 KR KR1019970702787A patent/KR100473219B1/ko not_active Expired - Fee Related
- 1995-10-26 CA CA002203765A patent/CA2203765C/en not_active Expired - Fee Related
- 1995-10-26 WO PCT/US1995/013820 patent/WO1996013523A1/en not_active Ceased
- 1995-10-26 ES ES95937639T patent/ES2256849T3/es not_active Expired - Lifetime
- 1995-10-26 AT AT95937639T patent/ATE317441T1/de not_active IP Right Cessation
- 1995-10-26 DE DE69534778T patent/DE69534778T2/de not_active Expired - Fee Related
- 1995-10-26 HU HU9701942A patent/HU220960B1/hu not_active IP Right Cessation
- 1995-10-26 NZ NZ296003A patent/NZ296003A/en unknown
- 1995-10-26 EP EP95937639A patent/EP0783527B1/de not_active Revoked
- 1995-10-26 FI FI971777A patent/FI971777A7/fi not_active Application Discontinuation
- 1995-10-26 CN CNB951968416A patent/CN1148382C/zh not_active Expired - Fee Related
-
1997
- 1997-04-23 NO NO971875A patent/NO971875L/no not_active Application Discontinuation
-
2002
- 2002-12-13 US US10/318,584 patent/US20030175937A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| NO971875D0 (no) | 1997-04-23 |
| ES2256849T3 (es) | 2006-07-16 |
| KR100473219B1 (ko) | 2005-05-16 |
| US20030175937A1 (en) | 2003-09-18 |
| FI971777A0 (fi) | 1997-04-25 |
| DE69534778T2 (de) | 2006-08-17 |
| CN1170415A (zh) | 1998-01-14 |
| EP0783527A1 (de) | 1997-07-16 |
| AU3968895A (en) | 1996-05-23 |
| AU711810B2 (en) | 1999-10-21 |
| HUT77049A (hu) | 1998-03-02 |
| NO971875L (no) | 1997-06-12 |
| WO1996013523A1 (en) | 1996-05-09 |
| DE69534778D1 (en) | 2006-04-20 |
| FI971777A7 (fi) | 1997-04-25 |
| JPH10512740A (ja) | 1998-12-08 |
| KR970707153A (ko) | 1997-12-01 |
| CN1148382C (zh) | 2004-05-05 |
| EP0783527A4 (de) | 1998-12-02 |
| ATE317441T1 (de) | 2006-02-15 |
| EP0783527B1 (de) | 2006-02-08 |
| CA2203765C (en) | 2002-04-23 |
| NZ296003A (en) | 1999-10-28 |
| CA2203765A1 (en) | 1996-05-09 |
| HU220960B1 (hu) | 2002-07-29 |
| JP3670666B2 (ja) | 2005-07-13 |
| US6544767B1 (en) | 2003-04-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |