ATE317441T1 - Cathepsin-02-protease - Google Patents

Cathepsin-02-protease

Info

Publication number
ATE317441T1
ATE317441T1 AT95937639T AT95937639T ATE317441T1 AT E317441 T1 ATE317441 T1 AT E317441T1 AT 95937639 T AT95937639 T AT 95937639T AT 95937639 T AT95937639 T AT 95937639T AT E317441 T1 ATE317441 T1 AT E317441T1
Authority
AT
Austria
Prior art keywords
cathepsin
protease
antibodies
proteins
relates
Prior art date
Application number
AT95937639T
Other languages
English (en)
Inventor
Dieter Broemme
Kathleen Okamoto
Original Assignee
Arris Pharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26987129&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE317441(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/330,121 external-priority patent/US5736357A/en
Application filed by Arris Pharm Corp filed Critical Arris Pharm Corp
Application granted granted Critical
Publication of ATE317441T1 publication Critical patent/ATE317441T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6472—Cysteine endopeptidases (3.4.22)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT95937639T 1994-10-27 1995-10-26 Cathepsin-02-protease ATE317441T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/330,121 US5736357A (en) 1994-10-27 1994-10-27 Cathespin O protease
US08/536,861 US6544767B1 (en) 1994-10-27 1995-10-02 Cathespin O2 protease

Publications (1)

Publication Number Publication Date
ATE317441T1 true ATE317441T1 (de) 2006-02-15

Family

ID=26987129

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95937639T ATE317441T1 (de) 1994-10-27 1995-10-26 Cathepsin-02-protease

Country Status (15)

Country Link
US (2) US6544767B1 (de)
EP (1) EP0783527B1 (de)
JP (1) JP3670666B2 (de)
KR (1) KR100473219B1 (de)
CN (1) CN1148382C (de)
AT (1) ATE317441T1 (de)
AU (1) AU711810B2 (de)
CA (1) CA2203765C (de)
DE (1) DE69534778T2 (de)
ES (1) ES2256849T3 (de)
FI (1) FI971777L (de)
HU (1) HU220960B1 (de)
NO (1) NO971875L (de)
NZ (1) NZ296003A (de)
WO (1) WO1996013523A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403304B1 (en) 1993-04-06 2002-06-11 Forsyth Dental Infirmary For Children Human osteoclast-specific and -related DNA sequences
US5501969A (en) 1994-03-08 1996-03-26 Human Genome Sciences, Inc. Human osteoclast-derived cathepsin
US6586466B2 (en) 1995-10-30 2003-07-01 Smithkline Beecham Corporation Carbohydrazide-protease inhibitors
CN1177293A (zh) 1995-10-30 1998-03-25 史密丝克莱恩比彻姆公司 抑制组织蛋白酶k的方法
CZ132798A3 (cs) 1995-10-30 1999-02-17 Smithkline Beecham Corporation Inhibitory proteázy
EP0812916A3 (de) * 1996-06-14 1998-12-09 Smithkline Beecham Corporation Cathepsin K Gen
AU3802297A (en) * 1996-07-03 1998-01-21 Novadx, Inc. Method for detecting degenerative bone disease
GB9701888D0 (en) * 1997-01-30 1997-03-19 Ciba Geigy Ag Novel methods
US5948669A (en) * 1997-02-26 1999-09-07 Smithkline Beecham Corporation Rat cathepsin K polynucleotide and polypeptide sequence
US20030144175A1 (en) 1998-12-23 2003-07-31 Smithkline Beecham Corporation Protease inhibitors
US6346373B1 (en) * 1999-05-05 2002-02-12 Merck Frosst Canada & Co., Whole cell assay for cathepsin K activity
AU6199100A (en) * 1999-06-25 2001-01-31 Hybritech Incorporated Cloning and expressing of human cathepsin k in mammalian cells
EP1232155A4 (de) 1999-11-10 2002-11-20 Smithkline Beecham Corp Protease inhibitoren
EP1232154A4 (de) 1999-11-10 2004-06-23 Smithkline Beecham Corp Protease inhibitoren
WO2001034156A1 (en) 1999-11-10 2001-05-17 Smithkline Beecham Corporation Protease inhibitors
WO2001053297A1 (en) 2000-01-20 2001-07-26 Merck & Co., Inc. Alpha v integrin receptor antagonists
IL150964A0 (en) 2000-03-21 2003-02-12 Smithkline Beecham Corp Protease inhibitors
EP1387886A2 (de) * 2000-10-18 2004-02-11 Incyte Genomics, Inc. Proteasen
WO2003106677A1 (ja) * 2002-06-17 2003-12-24 株式会社ニチレイ ホッコクアカエビ由来の新規なカテプシンl様システインプロテアーゼ
WO2004000838A1 (en) * 2002-06-24 2003-12-31 Axys Pharmaceuticals, Inc. Peptidic compounds as cysteine protease inhibitors
CA2532948A1 (en) * 2003-07-21 2005-02-17 Novartis Ag Combinations of a cathepsin k inhibitor and a bisphophonate in the treatment of bone metastasis, tumor growth and tumor-induced bone loss
CA2535359A1 (en) 2003-08-21 2005-03-03 Merck Frosst Canada Ltd. Cathepsin cysteine protease inhibitors
US20070015234A1 (en) * 2003-09-23 2007-01-18 Sylvie Desmarais Whole cell assay for inhibitors of cathepsin k
WO2005093421A1 (de) * 2004-03-10 2005-10-06 Biovendor Laboratory Medicine, Inc. Enzymimmunoassay zur bestimmung von cathepsin k
US7029902B2 (en) * 2004-03-26 2006-04-18 Applera Corporation Isolated monkey cathepsin S proteins, nucleic acid molecules encoding monkey cathepsin S proteins, and uses thereof
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
AU2013202011C1 (en) * 2008-03-06 2015-10-01 Halozyme, Inc. In vivo temporal control of activatable matrix-degrading enzymes
TWI395593B (zh) * 2008-03-06 2013-05-11 Halozyme Inc 可活化的基質降解酵素之活體內暫時性控制
EP2953948B1 (de) 2013-02-07 2017-09-27 Scifluor Life Sciences, Inc Fluorierte integrin-antagonisten
US8901144B2 (en) 2013-02-07 2014-12-02 Scifluor Life Sciences, Llc Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives
CA2950390C (en) 2014-05-30 2020-09-22 Pfizer Inc. Carbonitrile derivatives as selective androgen receptor modulators
AU2016219906B2 (en) 2015-02-19 2020-10-01 Scifluor Life Sciences, Inc. Fluorinated tetrahydronaphthyridinyl nonanoic acid derivatives and uses thereof
WO2023275715A1 (en) 2021-06-30 2023-01-05 Pfizer Inc. Metabolites of selective androgen receptor modulators

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5501969A (en) 1994-03-08 1996-03-26 Human Genome Sciences, Inc. Human osteoclast-derived cathepsin
AU6333296A (en) 1996-06-14 1998-01-07 Human Genome Sciences, Inc. Cathepsin k gene

Also Published As

Publication number Publication date
EP0783527B1 (de) 2006-02-08
CN1148382C (zh) 2004-05-05
NO971875D0 (no) 1997-04-23
KR970707153A (ko) 1997-12-01
DE69534778D1 (en) 2006-04-20
CA2203765A1 (en) 1996-05-09
NO971875L (no) 1997-06-12
KR100473219B1 (ko) 2005-05-16
FI971777A0 (fi) 1997-04-25
FI971777A7 (fi) 1997-04-25
HUT77049A (hu) 1998-03-02
ES2256849T3 (es) 2006-07-16
HU220960B1 (hu) 2002-07-29
CN1170415A (zh) 1998-01-14
FI971777L (fi) 1997-04-25
US20030175937A1 (en) 2003-09-18
WO1996013523A1 (en) 1996-05-09
JP3670666B2 (ja) 2005-07-13
JPH10512740A (ja) 1998-12-08
AU711810B2 (en) 1999-10-21
AU3968895A (en) 1996-05-23
EP0783527A1 (de) 1997-07-16
US6544767B1 (en) 2003-04-08
EP0783527A4 (de) 1998-12-02
NZ296003A (en) 1999-10-28
DE69534778T2 (de) 2006-08-17
CA2203765C (en) 2002-04-23

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