FR05C0027I2 - - Google Patents
Info
- Publication number
- FR05C0027I2 FR05C0027I2 FR05C0027C FR05C0027C FR05C0027I2 FR 05C0027 I2 FR05C0027 I2 FR 05C0027I2 FR 05C0027 C FR05C0027 C FR 05C0027C FR 05C0027 C FR05C0027 C FR 05C0027C FR 05C0027 I2 FR05C0027 I2 FR 05C0027I2
- Authority
- FR
- France
- Prior art keywords
- conopeptide
- omega
- medicament
- manufacture
- disclosed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 208000004296 neuralgia Diseases 0.000 abstract 1
- 208000021722 neuropathic pain Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Control Of El Displays (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/496,847 US5795864A (en) | 1995-06-27 | 1995-06-27 | Stable omega conopetide formulations |
| US08/613,400 US6054429A (en) | 1996-03-08 | 1996-03-08 | Epidural method of producing analgesia |
| PCT/US1996/011041 WO1997001351A1 (en) | 1995-06-27 | 1996-06-26 | Compositions and formulations for producing analgesia and for inhibiting progression of neuropathic pain disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR05C0027I1 FR05C0027I1 (2) | 2005-08-12 |
| FR05C0027I2 true FR05C0027I2 (2) | 2006-12-29 |
Family
ID=27052304
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR05C0027C Active FR05C0027I2 (2) | 1995-06-27 | 2005-06-23 |
Country Status (13)
| Country | Link |
|---|---|
| EP (2) | EP1336409B1 (2) |
| JP (1) | JP2838073B2 (2) |
| AT (2) | ATE359086T1 (2) |
| AU (1) | AU695166B2 (2) |
| CA (1) | CA2224795C (2) |
| DE (3) | DE69627153T2 (2) |
| DK (2) | DK0835126T3 (2) |
| ES (2) | ES2283671T3 (2) |
| FR (1) | FR05C0027I2 (2) |
| LU (1) | LU91181I2 (2) |
| NL (1) | NL300201I2 (2) |
| PT (2) | PT1336409E (2) |
| WO (1) | WO1997001351A1 (2) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5931809A (en) | 1995-07-14 | 1999-08-03 | Depotech Corporation | Epidural administration of therapeutic compounds with sustained rate of release |
| JP2002509080A (ja) * | 1998-02-20 | 2002-03-26 | シンジェンタ リミテッド | グラモストラ・スパチュラタの毒から得られる鎮痛性ペプチドおよびその使用 |
| AUPP627498A0 (en) | 1998-10-02 | 1998-10-22 | University Of Queensland, The | Novel peptides - i |
| EP2412719A1 (en) | 2002-12-02 | 2012-02-01 | Xenome Ltd | Chi-conotoxin peptides |
| WO2004050690A1 (en) | 2002-12-02 | 2004-06-17 | Xenome Ltd | NOVEL χ-CONOTOXIN PEPTIDES (-I) |
| SG168407A1 (en) | 2003-01-28 | 2011-02-28 | Ironwood Pharmaceuticals Inc | Methods and compositions for the treatment of gastrointestinal disorders |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US7268109B2 (en) | 2003-10-02 | 2007-09-11 | Elan Pharmaceuticals, Inc. | Method for reducing pain |
| GB0410215D0 (en) * | 2004-05-07 | 2004-06-09 | Lescroart Pol | Nerve damage |
| US8188048B2 (en) | 2006-06-23 | 2012-05-29 | Xenome Limited | Combination therapy |
| US8673856B2 (en) * | 2006-11-04 | 2014-03-18 | Anygen Co., Ltd. | Omega conotoxins |
| EP2527360B1 (en) | 2007-06-04 | 2015-10-28 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| WO2009135258A1 (en) * | 2008-05-06 | 2009-11-12 | Cnsbio Pty Ltd | Methods and compositions for the management of pain using omega-conotoxins |
| EP2810951B1 (en) | 2008-06-04 | 2017-03-15 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| EP3241839B1 (en) | 2008-07-16 | 2019-09-04 | Bausch Health Ireland Limited | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| CA2994066A1 (en) | 2008-12-03 | 2010-06-10 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase c agonists and methods of use |
| WO2018129556A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| SI2384318T1 (en) | 2008-12-31 | 2018-03-30 | Ardelyx, Inc. | MEASURES AND PROCEDURES FOR THE INHIBITION OF ANTIPORT INHIBITED BY NHE IN THE TREATMENT OF DISEASES RELATED TO STRENGTH OF FLAMMABILITY OR TRADEMARITY WITH SOLO, AND THE EMISSION OF GASTROINTESTINAL TREATMENT |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| MX366293B (es) | 2012-08-21 | 2019-07-04 | Ardelyx Inc | Compuestos y metodos para inhibir al antipuerto mediado por nhe en el tratamiento de trastornos asociados con la retencion de fluidos o la sobrecarga de sal y trastornos del tracto gastrointestinal. |
| US10376481B2 (en) | 2012-08-21 | 2019-08-13 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| CA2905435A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| CA2905438A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| LT2983667T (lt) | 2013-04-12 | 2019-07-10 | Ardelyx, Inc. | Nhe3 rišantys junginiai ir fosfato pernešimo slopinimo būdai |
| SI3004138T1 (sl) | 2013-06-05 | 2024-07-31 | Bausch Health Ireland Limited | Ultra čisti agonisti gvanilat ciklaze C, postopek za njihovo pripravo in uporabo |
| EA201991676A1 (ru) | 2017-01-09 | 2020-01-30 | Арделикс, Инк. | Ингибиторы nhe-опосредованного антипорта |
| CA3049678A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds useful for treating gastrointestinal tract disorders |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3926287A1 (de) * | 1989-08-09 | 1991-02-21 | Bernhard Clasbrummel | Medizinische anwendung von omega-conotoxin gvia oder omega-conotoxin gvia-analoga zur sympathikolyse |
| US5051403A (en) * | 1989-11-22 | 1991-09-24 | Neurex Corporation | Method of treating ischemia-related neuronal damage |
| WO1993010145A1 (en) * | 1991-11-12 | 1993-05-27 | Neurex Corporation | Compositions for delayed treatment of ischemia-related neuronal damage |
| SG50624A1 (en) * | 1991-12-30 | 1998-07-20 | Neurex Corp | Methods of producing analgesia and enhancing opiate analgesia |
| JPH06247879A (ja) * | 1993-02-17 | 1994-09-06 | Bristol Myers Squibb Co | デオキシチミジンヌクレオシドを含有する注射用製剤の安定化方法およびその方法によって得られる安定化注射用製剤 |
-
1996
- 1996-06-26 DE DE69627153T patent/DE69627153T2/de not_active Expired - Lifetime
- 1996-06-26 DK DK96923511T patent/DK0835126T3/da active
- 1996-06-26 AT AT03007342T patent/ATE359086T1/de active
- 1996-06-26 WO PCT/US1996/011041 patent/WO1997001351A1/en not_active Ceased
- 1996-06-26 DE DE69637021T patent/DE69637021T2/de not_active Expired - Lifetime
- 1996-06-26 ES ES03007342T patent/ES2283671T3/es not_active Expired - Lifetime
- 1996-06-26 AT AT96923511T patent/ATE235914T1/de active
- 1996-06-26 ES ES96923511T patent/ES2194998T3/es not_active Expired - Lifetime
- 1996-06-26 AU AU64002/96A patent/AU695166B2/en not_active Ceased
- 1996-06-26 DE DE1996627153 patent/DE122005000043I2/de active Active
- 1996-06-26 CA CA002224795A patent/CA2224795C/en not_active Expired - Fee Related
- 1996-06-26 EP EP03007342A patent/EP1336409B1/en not_active Expired - Lifetime
- 1996-06-26 PT PT03007342T patent/PT1336409E/pt unknown
- 1996-06-26 EP EP96923511A patent/EP0835126B1/en not_active Expired - Lifetime
- 1996-06-26 PT PT96923511T patent/PT835126E/pt unknown
- 1996-06-26 DK DK03007342T patent/DK1336409T3/da active
- 1996-06-27 JP JP8188120A patent/JP2838073B2/ja not_active Expired - Fee Related
-
2005
- 2005-06-23 FR FR05C0027C patent/FR05C0027I2/fr active Active
- 2005-07-06 LU LU91181C patent/LU91181I2/fr unknown
- 2005-07-13 NL NL300201C patent/NL300201I2/nl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE122005000043I2 (de) | 2006-08-03 |
| DK0835126T3 (da) | 2003-07-14 |
| JPH09104634A (ja) | 1997-04-22 |
| JP2838073B2 (ja) | 1998-12-16 |
| ES2194998T3 (es) | 2003-12-01 |
| AU6400296A (en) | 1997-01-30 |
| EP1336409B1 (en) | 2007-04-11 |
| LU91181I2 (fr) | 2005-09-06 |
| ATE235914T1 (de) | 2003-04-15 |
| ATE359086T1 (de) | 2007-05-15 |
| NL300201I1 (nl) | 2005-09-01 |
| EP1336409A1 (en) | 2003-08-20 |
| DE122005000043I1 (de) | 2006-06-29 |
| EP0835126A1 (en) | 1998-04-15 |
| DE69637021D1 (de) | 2007-05-24 |
| DE69637021T2 (de) | 2008-01-10 |
| PT835126E (pt) | 2003-07-31 |
| AU695166B2 (en) | 1998-08-06 |
| DE69627153T2 (de) | 2003-12-04 |
| FR05C0027I1 (2) | 2005-08-12 |
| WO1997001351A1 (en) | 1997-01-16 |
| HK1058146A1 (en) | 2004-05-07 |
| DK1336409T3 (da) | 2007-08-13 |
| PT1336409E (pt) | 2007-06-29 |
| CA2224795A1 (en) | 1997-01-16 |
| CA2224795C (en) | 2001-04-03 |
| ES2283671T3 (es) | 2007-11-01 |
| NL300201I2 (nl) | 2006-02-01 |
| EP0835126B1 (en) | 2003-04-02 |
| DE69627153D1 (de) | 2003-05-08 |
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