FR2000281A1 - Compn contng polyestriol phosphate for treatment of - Google Patents
Compn contng polyestriol phosphate for treatment ofInfo
- Publication number
- FR2000281A1 FR2000281A1 FR6900505A FR6900505A FR2000281A1 FR 2000281 A1 FR2000281 A1 FR 2000281A1 FR 6900505 A FR6900505 A FR 6900505A FR 6900505 A FR6900505 A FR 6900505A FR 2000281 A1 FR2000281 A1 FR 2000281A1
- Authority
- FR
- France
- Prior art keywords
- contng
- compn
- treatment
- iii
- polyestriol phosphate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 229910019142 PO4 Inorganic materials 0.000 title abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title abstract 2
- 239000010452 phosphate Substances 0.000 title abstract 2
- HZAXFHJVJLSVMW-UHFFFAOYSA-N 2-Aminoethan-1-ol Chemical compound NCCO HZAXFHJVJLSVMW-UHFFFAOYSA-N 0.000 abstract 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 abstract 1
- UEEJHVSXFDXPFK-UHFFFAOYSA-N N-dimethylaminoethanol Chemical compound CN(C)CCO UEEJHVSXFDXPFK-UHFFFAOYSA-N 0.000 abstract 1
- YQKAVWCGQQXBGW-UHFFFAOYSA-N Piperocaine Chemical compound CC1CCCCN1CCCOC(=O)C1=CC=CC=C1 YQKAVWCGQQXBGW-UHFFFAOYSA-N 0.000 abstract 1
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 abstract 1
- 230000003444 anaesthetic effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229960002023 chloroprocaine Drugs 0.000 abstract 1
- VDANGULDQQJODZ-UHFFFAOYSA-N chloroprocaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1Cl VDANGULDQQJODZ-UHFFFAOYSA-N 0.000 abstract 1
- 229960002887 deanol Drugs 0.000 abstract 1
- ZBCBWPMODOFKDW-UHFFFAOYSA-N diethanolamine Chemical compound OCCNCCO ZBCBWPMODOFKDW-UHFFFAOYSA-N 0.000 abstract 1
- HPNMFZURTQLUMO-UHFFFAOYSA-N diethylamine Chemical compound CCNCC HPNMFZURTQLUMO-UHFFFAOYSA-N 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 229960004194 lidocaine Drugs 0.000 abstract 1
- -1 menocaine Chemical compound 0.000 abstract 1
- 230000009245 menopause Effects 0.000 abstract 1
- 229960002409 mepivacaine Drugs 0.000 abstract 1
- INWLQCZOYSRPNW-UHFFFAOYSA-N mepivacaine Chemical compound CN1CCCCC1C(=O)NC1=C(C)C=CC=C1C INWLQCZOYSRPNW-UHFFFAOYSA-N 0.000 abstract 1
- 229960001045 piperocaine Drugs 0.000 abstract 1
- 229960004919 procaine Drugs 0.000 abstract 1
- MFDFERRIHVXMIY-UHFFFAOYSA-N procaine Chemical compound CCN(CC)CCOC(=O)C1=CC=C(N)C=C1 MFDFERRIHVXMIY-UHFFFAOYSA-N 0.000 abstract 1
- 230000002035 prolonged effect Effects 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Injectable soln. contng. polyestriol phosphate (I), a local anaesthetic (II) and a solubilising agent (III) at pH 6.3-7.5. Treatment of menopause symptoms. The compns. show prolonged effects. (1-2 months between injections). Compn. conts. 2-12% (I), 0.25-4% (II) and 0.75-12% (III). (II) may be mepivacaine, chloroprocaine, menocaine, piperocaine, procaine, or lidocaine, and (III) may be nicotinamide, morpholine, diethanolamine, diethylamine, ethanolamine or dimethylaminoethanol. Dose: 20-100 mg(I).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69815268A | 1968-01-16 | 1968-01-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2000281A1 true FR2000281A1 (en) | 1969-09-05 |
Family
ID=24804122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR6900505A Withdrawn FR2000281A1 (en) | 1968-01-16 | 1969-01-15 | Compn contng polyestriol phosphate for treatment of |
Country Status (2)
| Country | Link |
|---|---|
| BE (1) | BE726959A (en) |
| FR (1) | FR2000281A1 (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB778142A (en) * | 1953-11-20 | 1957-07-03 | Leo Ab | High-molecular weight derivatives of hydroxyl group-containing steroids and a method of producing them |
-
1969
- 1969-01-15 FR FR6900505A patent/FR2000281A1/en not_active Withdrawn
- 1969-01-16 BE BE726959D patent/BE726959A/xx unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB778142A (en) * | 1953-11-20 | 1957-07-03 | Leo Ab | High-molecular weight derivatives of hydroxyl group-containing steroids and a method of producing them |
Non-Patent Citations (1)
| Title |
|---|
| LA *REVUE "UNLISTED DRUGS", 1968, PAGE 8C CITE: "MBR. INTERKANT KONTR. HEILM." 67:415, SEPT. 67 * |
Also Published As
| Publication number | Publication date |
|---|---|
| BE726959A (en) | 1969-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |