FR2070005A2 - (n-(2-pyrimidinyl)-b22-ornithine)-insulins- prolonged action hypoglyc - anabolic used to treat schizophrenia and in healing - Google Patents

(n-(2-pyrimidinyl)-b22-ornithine)-insulins- prolonged action hypoglyc - anabolic used to treat schizophrenia and in healing

Info

Publication number
FR2070005A2
FR2070005A2 FR6944788A FR6944788A FR2070005A2 FR 2070005 A2 FR2070005 A2 FR 2070005A2 FR 6944788 A FR6944788 A FR 6944788A FR 6944788 A FR6944788 A FR 6944788A FR 2070005 A2 FR2070005 A2 FR 2070005A2
Authority
FR
France
Prior art keywords
insulins
ornithine
pyrimidinyl
hypoglyc
anabolic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR6944788A
Other languages
French (fr)
Other versions
FR2070005B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR6944788A priority Critical patent/FR2070005A2/en
Publication of FR2070005A2 publication Critical patent/FR2070005A2/en
Application granted granted Critical
Publication of FR2070005B2 publication Critical patent/FR2070005B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • C07K14/625—Extraction from natural sources
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Salts of tris-NA1, NB1, NEB29-Q- N8-4-Z6-R-pyrimidinyl-2)-B22-ornithine -insulins and the free non-salified insulins are novel cpds. The salts are water-soluble and the cpds. exist in a dissociated or weakly associated state having formula: (where Q = CH3CO, CH3CO-C=CH-, H2N-CO-, HN=C(NH2)-; Z, R = alkyl, aralkyl, aryl .
FR6944788A 1969-12-24 1969-12-24 (n-(2-pyrimidinyl)-b22-ornithine)-insulins- prolonged action hypoglyc - anabolic used to treat schizophrenia and in healing Granted FR2070005A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR6944788A FR2070005A2 (en) 1969-12-24 1969-12-24 (n-(2-pyrimidinyl)-b22-ornithine)-insulins- prolonged action hypoglyc - anabolic used to treat schizophrenia and in healing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR6944788A FR2070005A2 (en) 1969-12-24 1969-12-24 (n-(2-pyrimidinyl)-b22-ornithine)-insulins- prolonged action hypoglyc - anabolic used to treat schizophrenia and in healing

Publications (2)

Publication Number Publication Date
FR2070005A2 true FR2070005A2 (en) 1971-09-10
FR2070005B2 FR2070005B2 (en) 1973-01-12

Family

ID=9045129

Family Applications (1)

Application Number Title Priority Date Filing Date
FR6944788A Granted FR2070005A2 (en) 1969-12-24 1969-12-24 (n-(2-pyrimidinyl)-b22-ornithine)-insulins- prolonged action hypoglyc - anabolic used to treat schizophrenia and in healing

Country Status (1)

Country Link
FR (1) FR2070005A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1468831A (en) * 1965-10-05 1967-02-10 Roussel Uclaf Process for the preparation of novel polypeptide compounds and resulting products

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1468831A (en) * 1965-10-05 1967-02-10 Roussel Uclaf Process for the preparation of novel polypeptide compounds and resulting products

Also Published As

Publication number Publication date
FR2070005B2 (en) 1973-01-12

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