FR2070126A1 - New 2-(2-alkyl-4-amino-5-pyrimidinylmethyl)- - quinolinium salts as anti-coccidiosis agents - Google Patents
New 2-(2-alkyl-4-amino-5-pyrimidinylmethyl)- - quinolinium salts as anti-coccidiosis agentsInfo
- Publication number
- FR2070126A1 FR2070126A1 FR7036980A FR7036980A FR2070126A1 FR 2070126 A1 FR2070126 A1 FR 2070126A1 FR 7036980 A FR7036980 A FR 7036980A FR 7036980 A FR7036980 A FR 7036980A FR 2070126 A1 FR2070126 A1 FR 2070126A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- pyrimidinylmethyl
- amino
- new
- quinolinium salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 208000003495 Coccidiosis Diseases 0.000 title abstract 2
- 206010023076 Isosporiasis Diseases 0.000 title abstract 2
- SMWDFEZZVXVKRB-UHFFFAOYSA-N Quinoline Chemical compound N1=CC=CC2=CC=CC=C21 SMWDFEZZVXVKRB-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- PUAQLLVFLMYYJJ-UHFFFAOYSA-N 2-aminopropiophenone Chemical compound CC(N)C(=O)C1=CC=CC=C1 PUAQLLVFLMYYJJ-UHFFFAOYSA-N 0.000 abstract 1
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical compound C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 230000001165 anti-coccidial effect Effects 0.000 abstract 1
- 238000010348 incorporation Methods 0.000 abstract 1
- 244000144977 poultry Species 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000011592 zinc chloride Substances 0.000 abstract 1
- 235000005074 zinc chloride Nutrition 0.000 abstract 1
- JIAARYAFYJHUJI-UHFFFAOYSA-L zinc dichloride Chemical compound [Cl-].[Cl-].[Zn+2] JIAARYAFYJHUJI-UHFFFAOYSA-L 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
New quat. 1-(2-alkyl-4-amino-5-pyrimidinylmethyl)-quinolinium salts of formula (I), possessing anti-coccidial activity are useful in the prevention and treatment of coccidiosis in poultry by incorporation in the feed, are prepd. by reaction of pyrimidine derivs. (II) with quinoline derivs. (III) and quaternisation. (where R = lower alkyl; R' = H or lower alkyl; Y = an anion). When Y = Cl, treatment of the compd. with ZnCl2 gives a complex with Y = ZnCl24-.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUCI000925 | 1969-10-14 | ||
| HUCI000926 | 1969-10-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2070126A1 true FR2070126A1 (en) | 1971-09-10 |
Family
ID=26318382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7036980A Withdrawn FR2070126A1 (en) | 1969-10-14 | 1970-10-13 | New 2-(2-alkyl-4-amino-5-pyrimidinylmethyl)- - quinolinium salts as anti-coccidiosis agents |
Country Status (4)
| Country | Link |
|---|---|
| DE (1) | DE2049009A1 (en) |
| ES (1) | ES384445A1 (en) |
| FR (1) | FR2070126A1 (en) |
| IL (1) | IL35438A0 (en) |
-
1970
- 1970-10-06 DE DE19702049009 patent/DE2049009A1/en active Pending
- 1970-10-12 IL IL35438A patent/IL35438A0/en unknown
- 1970-10-13 ES ES384445A patent/ES384445A1/en not_active Expired
- 1970-10-13 FR FR7036980A patent/FR2070126A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| IL35438A0 (en) | 1970-12-24 |
| ES384445A1 (en) | 1974-06-01 |
| DE2049009A1 (en) | 1971-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Withdrawal of published application |