FR2070145A1 - Furopyran derivs with cytotoxic activity - Google Patents
Furopyran derivs with cytotoxic activityInfo
- Publication number
- FR2070145A1 FR2070145A1 FR7037305A FR7037305A FR2070145A1 FR 2070145 A1 FR2070145 A1 FR 2070145A1 FR 7037305 A FR7037305 A FR 7037305A FR 7037305 A FR7037305 A FR 7037305A FR 2070145 A1 FR2070145 A1 FR 2070145A1
- Authority
- FR
- France
- Prior art keywords
- derivs
- beta
- furopyran
- cytotoxic activity
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- OMICGTSJVWEQMZ-UHFFFAOYSA-N 5h-furo[3,2-b]pyran Chemical compound C1=CCOC2=C1OC=C2 OMICGTSJVWEQMZ-UHFFFAOYSA-N 0.000 title abstract 2
- 230000001472 cytotoxic effect Effects 0.000 title abstract 2
- XXBVEGKVQYREKW-UHFFFAOYSA-N 2-(furan-3-yl)ethanol Chemical compound OCCC=1C=COC=1 XXBVEGKVQYREKW-UHFFFAOYSA-N 0.000 abstract 1
- 239000012024 dehydrating agents Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Furopyran derivs. with cytotoxic activity. Novel cpds. having th} partial structure:- (where R1 and R2 are H or opt. substd. hydrocarbyl) may be used for treating virus infections and neoplastic diseases, and may be prepd. from the corresp. beta-(3-furyl)- ethanol derivs. by treating with a dehydrating agent at 150 degrees C. Preferred products include 6',6'-dimethyl, 6'-methyl- and 6'-phenyl-5 beta,14 beta-6'H-androstano 16,1-2'-,3' furo 3", 2"-4', 5' pyran-3 beta, 14-diol.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8370869 | 1969-10-20 | ||
| JP45086189A JPS5010600B1 (en) | 1970-10-01 | 1970-10-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2070145A1 true FR2070145A1 (en) | 1971-09-10 |
| FR2070145B1 FR2070145B1 (en) | 1973-12-21 |
Family
ID=26424738
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7037305A Granted FR2070145A1 (en) | 1969-10-20 | 1970-10-15 | Furopyran derivs with cytotoxic activity |
Country Status (2)
| Country | Link |
|---|---|
| DE (1) | DE2051496A1 (en) |
| FR (1) | FR2070145A1 (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3939178A (en) * | 1971-06-01 | 1976-02-17 | American Home Products Corporation | Certain pyrano [3,4-b]indoles and thiopyrano[3,4-b]indoles |
| US3880853A (en) * | 1972-01-13 | 1975-04-29 | Ayerst Mckenna & Harrison | Pyrano-and thiopyranoindole |
| US4118394A (en) * | 1976-10-18 | 1978-10-03 | Ayerst, Mckenna & Harrison Limited | Pyrano- and thiopyranoindole derivatives |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1201360B (en) * | 1962-12-12 | 1965-09-23 | Hoechst Ag | Process for the preparation of 2, 5-diisopropyl-3, 3-dimethyl-tetrahydrofuranone- (4) |
-
1970
- 1970-10-15 FR FR7037305A patent/FR2070145A1/en active Granted
- 1970-10-20 DE DE19702051496 patent/DE2051496A1/de active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1201360B (en) * | 1962-12-12 | 1965-09-23 | Hoechst Ag | Process for the preparation of 2, 5-diisopropyl-3, 3-dimethyl-tetrahydrofuranone- (4) |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2051496A1 (en) | 1971-04-29 |
| FR2070145B1 (en) | 1973-12-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |