FR2071570A5 - Creatinol o-phosphate prepn - Google Patents

Creatinol o-phosphate prepn

Info

Publication number
FR2071570A5
FR2071570A5 FR7009190A FR7009190A FR2071570A5 FR 2071570 A5 FR2071570 A5 FR 2071570A5 FR 7009190 A FR7009190 A FR 7009190A FR 7009190 A FR7009190 A FR 7009190A FR 2071570 A5 FR2071570 A5 FR 2071570A5
Authority
FR
France
Prior art keywords
creatinol
treating
phosphate
prepn
soln
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7009190A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siphar SA
Original Assignee
Siphar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siphar SA filed Critical Siphar SA
Application granted granted Critical
Publication of FR2071570A5 publication Critical patent/FR2071570A5/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/091—Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Title cpd. which is useful for treating myocardiopathies, is prepd. by converting creatinol hydrobromide into the salt of creatinol with orthophosphoric acid (e.g. by treating an alcoholic soln. of the hydrobormide with NaOH and treating the resulting soln. with H3PO4) and dehydrating the phosphate salt (e.g. heating in vacuo at 160-200 degrees C).
FR7009190A 1969-11-18 1970-03-13 Creatinol o-phosphate prepn Expired FR2071570A5 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1724069A CH516596A (en) 1969-11-18 1969-11-18 New process for the preparation of creatinol phosphoric ester (creatinol O-phosphate)

Publications (1)

Publication Number Publication Date
FR2071570A5 true FR2071570A5 (en) 1971-09-17

Family

ID=4423853

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7009190A Expired FR2071570A5 (en) 1969-11-18 1970-03-13 Creatinol o-phosphate prepn

Country Status (4)

Country Link
JP (1) JPS4821930B1 (en)
CH (1) CH516596A (en)
DE (1) DE2006484C3 (en)
FR (1) FR2071570A5 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101671358B (en) * 2009-10-16 2012-07-11 天津天成制药有限公司 Preparation method for creatinol-O-organic phosphate
CN106117087A (en) * 2016-07-13 2016-11-16 启东瑞华药业有限公司 A kind of creatinol method for production of phosphate salt
CN107445984B (en) * 2017-07-26 2019-07-19 泰山医学院 A kind of preparation method of creatinol-o-phosphate

Also Published As

Publication number Publication date
DE2006484C3 (en) 1973-09-13
DE2006484B2 (en) 1973-02-15
JPS4821930B1 (en) 1973-07-02
CH516596A (en) 1971-12-15
DE2006484A1 (en) 1971-07-08

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Legal Events

Date Code Title Description
ST Notification of lapse