FR2073427A1 - 4-methyl-5-ethyl-n-heterocyclic thiazoles - with antianoxic activity - Google Patents

4-methyl-5-ethyl-n-heterocyclic thiazoles - with antianoxic activity

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Publication number
FR2073427A1
FR2073427A1 FR7041137A FR7041137A FR2073427A1 FR 2073427 A1 FR2073427 A1 FR 2073427A1 FR 7041137 A FR7041137 A FR 7041137A FR 7041137 A FR7041137 A FR 7041137A FR 2073427 A1 FR2073427 A1 FR 2073427A1
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FR
France
Prior art keywords
heterocyclic
cpds
thiazoles
ethyl
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7041137A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SOGERAS
Original Assignee
SOGERAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SOGERAS filed Critical SOGERAS
Publication of FR2073427A1 publication Critical patent/FR2073427A1/en
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)

Abstract

4-Methyl-5- ethyl-N-heterocyclic thiazoles - with antianoxic activity. Cpds. of formula: (where R is H, Me, Et or C6H5; Z is a nitrogen heterocycle connected via the N-atom, esp. morpholine, 2,6dimethylmorpholine, N-(2-aminoethyl)morpholine, imidazole, pyridazole, piperidine, pyrrodlidine, phthalimide, 1,2,3,4-tetrahydroquinoline, 1,2,3,4-tetrahydro-6-methylquinoline or N-methylpiperazine). The cpds. and their salts are anti-anoxic agents useful in treating ischaemic, and also have antipyretic and central anticholinergic activity. Cpds. are used at a daily dosage of 200-600 mg. Prepd. by treating the alpha-chloroethylthiazoles with appropriate N-heterocyclic cpds.
FR7041137A 1969-11-28 1970-11-17 4-methyl-5-ethyl-n-heterocyclic thiazoles - with antianoxic activity Withdrawn FR2073427A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5840769 1969-11-28

Publications (1)

Publication Number Publication Date
FR2073427A1 true FR2073427A1 (en) 1971-10-01

Family

ID=10481551

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7041137A Withdrawn FR2073427A1 (en) 1969-11-28 1970-11-17 4-methyl-5-ethyl-n-heterocyclic thiazoles - with antianoxic activity

Country Status (1)

Country Link
FR (1) FR2073427A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172137A (en) * 1976-08-11 1979-10-23 Roussel Uclaf 5-Thiazole-alkylamines used as antilipolytics
EP0244803A3 (en) * 1986-05-06 1991-01-16 Merrell Dow Pharmaceuticals Inc. Novel dopamine beta hydroxylase inhibitors
WO1991010656A1 (en) * 1990-01-19 1991-07-25 Cedona Pharmaceuticals B.V. Thiazole derivatives

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4172137A (en) * 1976-08-11 1979-10-23 Roussel Uclaf 5-Thiazole-alkylamines used as antilipolytics
EP0244803A3 (en) * 1986-05-06 1991-01-16 Merrell Dow Pharmaceuticals Inc. Novel dopamine beta hydroxylase inhibitors
WO1991010656A1 (en) * 1990-01-19 1991-07-25 Cedona Pharmaceuticals B.V. Thiazole derivatives

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