FR2106830A5 - 1-phenyl-2-styryl pyrazolin-5-one-3-yl salicylates - with antirheumatic activity - Google Patents
1-phenyl-2-styryl pyrazolin-5-one-3-yl salicylates - with antirheumatic activityInfo
- Publication number
- FR2106830A5 FR2106830A5 FR7034742A FR7034742A FR2106830A5 FR 2106830 A5 FR2106830 A5 FR 2106830A5 FR 7034742 A FR7034742 A FR 7034742A FR 7034742 A FR7034742 A FR 7034742A FR 2106830 A5 FR2106830 A5 FR 2106830A5
- Authority
- FR
- France
- Prior art keywords
- alkyl
- pyrazolin
- salicylates
- styryl
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 1-phenyl-2-styryl pyrazolin-5-one-3-yl salicylates Chemical class 0.000 title abstract 3
- 230000003356 anti-rheumatic effect Effects 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005055 alkyl alkoxy group Chemical group 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000002221 antipyretic Substances 0.000 abstract 1
- 229940125716 antipyretic agent Drugs 0.000 abstract 1
- 239000003435 antirheumatic agent Substances 0.000 abstract 1
- 239000011230 binding agent Substances 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- DNTVKOMHCDKATN-UHFFFAOYSA-N pyrazolidine-3,5-dione Chemical compound O=C1CC(=O)NN1 DNTVKOMHCDKATN-UHFFFAOYSA-N 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/28—Two oxygen or sulfur atoms
- C07D231/30—Two oxygen or sulfur atoms attached in positions 3 and 5
- C07D231/32—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Cpds of formula: where R=1-6C alkyl, 1-6C alkanoyl, R1=H,halogen, alkyl alkoxy, R2=1 or 2 optional halogen, alkyl or alkoxy substs. or R2 is a 3,4-methylenedioxy gp. R3, R4=H or 1-4C alkyl. The esters are antirheumatic, anti-inflammatory, analgesic, and antipyretic agents. They are prepd by treating the corresp. pyrazolidine-3,5-dione or its sodio-derivative with the desired salicyl halide, pref. in an inert liq. solvent, in presence of an acid-binding agent when the sodio-derivative is not used.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7034742A FR2106830A5 (en) | 1970-09-25 | 1970-09-25 | 1-phenyl-2-styryl pyrazolin-5-one-3-yl salicylates - with antirheumatic activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7034742A FR2106830A5 (en) | 1970-09-25 | 1970-09-25 | 1-phenyl-2-styryl pyrazolin-5-one-3-yl salicylates - with antirheumatic activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2106830A5 true FR2106830A5 (en) | 1972-05-05 |
Family
ID=9061847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7034742A Expired FR2106830A5 (en) | 1970-09-25 | 1970-09-25 | 1-phenyl-2-styryl pyrazolin-5-one-3-yl salicylates - with antirheumatic activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2106830A5 (en) |
-
1970
- 1970-09-25 FR FR7034742A patent/FR2106830A5/en not_active Expired
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES449655A1 (en) | Anti-inflammatory 1,2-benzisoxazole derivatives | |
| ES409436A1 (en) | Isoindoline derivatives | |
| GB1317210A (en) | Reduction of thebaine | |
| AU464808B2 (en) | Polymers of alkoxyalkyl acrylates, alkyl acrylates and substituted norbornene compounds | |
| SE7504842L (en) | PROCEDURE FOR THE PREPARATION OF ADENINE DERIVATIVES .. | |
| ES427893A1 (en) | Combating weeds in rice with benzothiazole derivatives | |
| FI53660C (en) | 3 - ((3-CARBAMOYL-2,4,6-TRIODOPHENOXY) -ALCOXY) -2-ALKYL-PROPIONSYROR THERE IS AN INTENDED COMPOSITION OF THE COMPOSITION OF THE RENTGENCOTRASMEDEL | |
| FR2106830A5 (en) | 1-phenyl-2-styryl pyrazolin-5-one-3-yl salicylates - with antirheumatic activity | |
| SE7711821L (en) | N-CHLORACETYL-N-PHENYL-ALANINE ESTERS FOR USE AS FUNGICIDES AND METHODS OF PREPARING THE ASSOCIATIONS | |
| NL7501739A (en) | BIPHENYLYL ALKANOYL AND ALKENOYL ACID DERIVATIVES. | |
| FI49963C (en) | Process for the preparation of antibacterially active 1: 1 and 2: 1 complexes of phosphanilic acid and 9-amino-3-nitroacridine. | |
| FR2094501A5 (en) | 3-salicyloyloxy derivatives of phenylbutazone - and analogues - with antiinflammatory antipyretic, analgesic, antirhe | |
| BG34037A3 (en) | METHOD FOR OBTAINING SUBSTITUTED N-METHYLENE DERIVATIVES OF THIENAMYCIN | |
| SE401829B (en) | PROCEDURE FOR THE PREPARATION OF 5-PHENYL-6,7-BENZOMORPHENE DERIVATIVES AND SALTS THEREOF | |
| ES408318A1 (en) | 1-Phenyl-3-hydroxy-3-methyl-triazenes | |
| FR2097031A1 (en) | 2-aminoethoxyethyl-6,6-dimethyl nor pinane derivs - local anaesthetics spasmolytics and anticholinergics | |
| SE400972B (en) | UNSATURATED PHOSPHORIC CARBONIC ACID DERIVATIVES USED FOR THE PREPARATION OF HOMO AND CO POLYMERIZATES WITH ACRYLIC ACID DERIVATIVES, STYRENES AND VINYL COMPOUNDS | |
| SE7904808L (en) | ESTER DERIVATIVES OF KINOLOPYRANE-4-ON-2-CARBOXYLIC ACIDS AND ANTIALLERGIC AGENTS FOR ASTHMA | |
| JPS5266626A (en) | Non-medical fungicide and anti-phytophagineae agent, and their prepara tion | |
| ES446051A1 (en) | Azabicycloalkanes | |
| FR2146952A1 (en) | 4-nicotinoylamido-1-phenyl-5-pyrazolones - with antiinflammatory analgesic, antipyretic and antirheumatic activity | |
| FR383M (en) | Anilinobenzoquinone derivatives. | |
| FR2085632A1 (en) | Glycylglycollic acid derivs - hepatoprojectors normolipemiants and hypocholesterol emiants | |
| FR2133025A5 (en) | 3-benzoyloxy-1,2-diphenylpyrazolin-5-ones - with antirheumatic and allied activities | |
| BE759106A (en) | Substd n-hydroxy propargyloxyphenylaceta - mide derivs, anti inflammatories |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |