FR2110141A5 - 2-thiazolyl-benzimidazoles prodn - from thiazole-4-carboxy- acid and ethylchloroformate with phenylenediamine via thiazolyl-carbo - Google Patents
2-thiazolyl-benzimidazoles prodn - from thiazole-4-carboxy- acid and ethylchloroformate with phenylenediamine via thiazolyl-carboInfo
- Publication number
- FR2110141A5 FR2110141A5 FR7139052A FR7139052A FR2110141A5 FR 2110141 A5 FR2110141 A5 FR 2110141A5 FR 7139052 A FR7139052 A FR 7139052A FR 7139052 A FR7139052 A FR 7139052A FR 2110141 A5 FR2110141 A5 FR 2110141A5
- Authority
- FR
- France
- Prior art keywords
- thiazolyl
- thiazole
- ethylchloroformate
- prodn
- benzimidazoles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GEYOCULIXLDCMW-UHFFFAOYSA-N 1,2-phenylenediamine Chemical compound NC1=CC=CC=C1N GEYOCULIXLDCMW-UHFFFAOYSA-N 0.000 title abstract 2
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 title abstract 2
- JBAITADHMBPOQQ-UHFFFAOYSA-N 2-(1h-benzimidazol-2-yl)-1,3-thiazole Chemical class C1=CSC(C=2NC3=CC=CC=C3N=2)=N1 JBAITADHMBPOQQ-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- ZMANZCXQSJIPKH-UHFFFAOYSA-N Triethylamine Chemical compound CCN(CC)CC ZMANZCXQSJIPKH-UHFFFAOYSA-N 0.000 abstract 3
- HMVYYTRDXNKRBQ-UHFFFAOYSA-N 1,3-thiazole-4-carboxylic acid Chemical compound OC(=O)C1=CSC=N1 HMVYYTRDXNKRBQ-UHFFFAOYSA-N 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 235000011007 phosphoric acid Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT3119170A IT1033046B (it) | 1970-10-31 | 1970-10-31 | Procedimento di fabbricazione di benzimidazoli sostituiti |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2110141A5 true FR2110141A5 (en) | 1972-05-26 |
Family
ID=11233253
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7139052A Expired FR2110141A5 (en) | 1970-10-31 | 1971-10-29 | 2-thiazolyl-benzimidazoles prodn - from thiazole-4-carboxy- acid and ethylchloroformate with phenylenediamine via thiazolyl-carbo |
Country Status (4)
| Country | Link |
|---|---|
| DE (1) | DE2062265A1 (it) |
| ES (1) | ES396567A1 (it) |
| FR (1) | FR2110141A5 (it) |
| IT (1) | IT1033046B (it) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1416928A2 (en) * | 2001-08-07 | 2004-05-12 | F. Hoffmann-La Roche Ag | N-monoacylated derivatives of o-phenylenediamines, their six membered heterocyclic analogues and their use as pharmaceutical agents |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200426138A (en) | 2002-12-10 | 2004-12-01 | Hoffmann La Roche | Novel arylene-carboxylic acid (2-amino-phenyl)-amide derivatives, their manufacture and use as pharmaceutical agents |
| TW200424174A (en) | 2003-02-06 | 2004-11-16 | Hoffmann La Roche | New TP diamide |
| US7208491B2 (en) | 2003-02-07 | 2007-04-24 | Hoffmann-La Roche Inc. | N-monoacylated o-phenylenediamines |
| TW200424187A (en) | 2003-04-04 | 2004-11-16 | Hoffmann La Roche | New oxime derivatives and their use as pharmaceutically active agents |
| KR101198057B1 (ko) | 2008-01-29 | 2012-11-07 | 에프. 호프만-라 로슈 아게 | 신규한 n-(2-아미노-페닐)-아미드 유도체 |
| MX2010012297A (es) | 2008-05-16 | 2010-12-06 | Hoffmann La Roche | Nuevas n-(2-amino-fenil)-acrilamidas. |
| US8202866B2 (en) | 2008-09-17 | 2012-06-19 | Hoffmann-La Roche Inc. | Ortho-aminoanilides for the treatment of cancer |
| BRPI1007995A2 (pt) | 2009-02-23 | 2019-09-24 | Hoffmann La Roche | orto-aminoamidas para o tratamento de cãncer. |
-
1970
- 1970-10-31 IT IT3119170A patent/IT1033046B/it active
- 1970-12-17 DE DE19702062265 patent/DE2062265A1/de active Pending
-
1971
- 1971-10-29 FR FR7139052A patent/FR2110141A5/fr not_active Expired
- 1971-10-30 ES ES396567A patent/ES396567A1/es not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1416928A2 (en) * | 2001-08-07 | 2004-05-12 | F. Hoffmann-La Roche Ag | N-monoacylated derivatives of o-phenylenediamines, their six membered heterocyclic analogues and their use as pharmaceutical agents |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2062265A1 (de) | 1972-05-18 |
| ES396567A1 (es) | 1974-05-16 |
| IT1033046B (it) | 1979-07-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE390894B (sv) | Forfarande for absorption av so71?3 eller fukt ur gasformiga medier med svavelsyra | |
| FR2110141A5 (en) | 2-thiazolyl-benzimidazoles prodn - from thiazole-4-carboxy- acid and ethylchloroformate with phenylenediamine via thiazolyl-carbo | |
| NO741549L (no) | Fremgangsmåte for fremstilling av akrylsyre og metakrylsyre ved omsetning av propylen eller isobutylen med molekylær oksygen | |
| IT956299B (it) | Procedimento per la produzione di corpi sagomati di carbonio | |
| GB1381320A (en) | Benzoxazole derivatives | |
| IT1057859B (it) | Perivato del triamoinolone | |
| TR18053A (tr) | O-etil-s, n-propil-o-/piridaz- (3)-on-6-il/tiono-fiolfosforik asid esterler, bunlarin en hazirlanmasina mahsus usul ve bunlarin en sektisidler ve akarisidler olarak kullanilmalari | |
| FR2186470A1 (en) | Purine nucleoside nitrates - for treating cardiac insufficiency | |
| IT943823B (it) | Procedimento per la preparazione di anidride maleica pura | |
| ES423716A1 (es) | Procedimiento para la obtencion de 1,4-dihidroquinolinas. | |
| SE394660B (sv) | Forfarande for framstellning av svavelsyra | |
| IT1000002B (it) | Procedimento per la produzione di acido l glutammico ed acido alfa chetoglutarico | |
| SU77367A2 (ru) | Способ интенсификации теплообмена | |
| SU78448A1 (ru) | Способ очистки лимонной кислоты | |
| FR2094444A5 (en) | Trichlorovinylsulphochloride prodn - with antibacterial and antifungal activity | |
| IT1050706B (it) | Processo per la preparazione del l 8 2 feniletil 1 ossa 3, 8 diazaspiro 4, 5 decan 2 one | |
| ES335892A1 (es) | Procedimiento para la preparacion de nitrocolorantes de la serie adridonica. | |
| SU76336A1 (ru) | Способ получени флуореион-2-сульфокислоты | |
| IT943822B (it) | Procedimento per la preparazione di anidride maleica pura | |
| GB1289072A (it) | ||
| IT974714B (it) | Procedimento per la produzione di elastasi mediante batteri | |
| SU83286A1 (ru) | Способ термической обработки изделий из углеродистой стали | |
| SE386668B (sv) | Forfarande for framstellning av tiodipropionsyraderivat | |
| FR2069758A5 (en) | 9 alpha -hydroxy-11 beta-nitrato-steroids | |
| ES405081A1 (es) | Procedimiento para la obtencion de dibenzo (d,f) dioxepinas-(1,3). |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |