FR2123196A1 - Extraction of bufotenidine - cardio tonic from toad venom - Google Patents

Extraction of bufotenidine - cardio tonic from toad venom

Info

Publication number: FR2123196A1
Authority: FR; France
Prior art keywords: bufotenidine; extraction; toad venom; treated; acid
Prior art date: 1971-01-28
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

FR7102896A

Other languages

English (en)

French (fr)

Other versions

FR2123196B1 (2

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Kyushin Seiyaku KK

Original Assignee

Kyushin Seiyaku KK

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-01-28

Filing date

1971-01-28

Publication date

1972-09-08

1971-01-28 Application filed by Kyushin Seiyaku KK filed Critical Kyushin Seiyaku KK

1971-01-28 Priority to FR7102896A priority Critical patent/FR2123196A1/fr

1972-09-08 Publication of FR2123196A1 publication Critical patent/FR2123196A1/fr

1974-04-12 Application granted granted Critical

1974-04-12 Publication of FR2123196B1 publication Critical patent/FR2123196B1/fr

Status Granted legal-status Critical Current

Links

239000003088 amphibian venom Substances 0.000 title abstract 2
HIYGARYIJIZXGW-UHFFFAOYSA-N bufotenidine Chemical compound C1=C([O-])C=C2C(CC[N+](C)(C)C)=CNC2=C1 HIYGARYIJIZXGW-UHFFFAOYSA-N 0.000 title abstract 2
230000003177 cardiotonic effect Effects 0.000 title 1
238000000605 extraction Methods 0.000 title 1
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 abstract 2
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 abstract 2
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
230000001476 alcoholic effect Effects 0.000 abstract 1
238000001704 evaporation Methods 0.000 abstract 1
230000008020 evaporation Effects 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229940075930 picrate Drugs 0.000 abstract 1
OXNIZHLAWKMVMX-UHFFFAOYSA-M picrate anion Chemical compound [O-]C1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-M 0.000 abstract 1
OXNIZHLAWKMVMX-UHFFFAOYSA-N picric acid Chemical compound OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
229910000030 sodium bicarbonate Inorganic materials 0.000 abstract 1
235000017557 sodium bicarbonate Nutrition 0.000 abstract 1
239000011780 sodium chloride Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

FR7102896A 1971-01-28 1971-01-28 Extraction of bufotenidine - cardio tonic from toad venom Granted FR2123196A1 (en)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
FR7102896A FR2123196A1 (en)	1971-01-28	1971-01-28	Extraction of bufotenidine - cardio tonic from toad venom

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR7102896A FR2123196A1 (en)	1971-01-28	1971-01-28	Extraction of bufotenidine - cardio tonic from toad venom

Publications (2)

Publication Number	Publication Date
FR2123196A1 true FR2123196A1 (en)	1972-09-08
FR2123196B1 FR2123196B1 (2)	1974-04-12

Family

ID=9071057

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR7102896A Granted FR2123196A1 (en)	1971-01-28	1971-01-28	Extraction of bufotenidine - cardio tonic from toad venom

Country Status (1)

Country	Link
FR (1)	FR2123196A1 (2)

1971
- 1971-01-28 FR FR7102896A patent/FR2123196A1/fr active Granted

Also Published As

Publication number	Publication date
FR2123196B1 (2)	1974-04-12

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Legal Events

Date	Code	Title	Description
1984-11-23	ST	Notification of lapse