FR2128348A1 - Mercapto-thienopyrimidine derivs - with sedative antitussive and hypocholesterolaemic activity - Google Patents

Mercapto-thienopyrimidine derivs - with sedative antitussive and hypocholesterolaemic activity

Info

Publication number: FR2128348A1
Authority: FR; France
Prior art keywords: derivs; thienopyrimidine; antitussive; sedative; mercapto
Prior art date: 1971-03-08
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

FR7206053A

Other languages

English (en)

Other versions

FR2128348B1 (fr

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

CENTRE ETD IND PHARMA

Original Assignee

CENTRE ETD IND PHARMA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-03-08

Filing date

1972-02-23

Publication date

1972-10-20

1972-02-23 Application filed by CENTRE ETD IND PHARMA filed Critical CENTRE ETD IND PHARMA

1972-10-20 Publication of FR2128348A1 publication Critical patent/FR2128348A1/fr

1975-10-10 Application granted granted Critical

1975-10-10 Publication of FR2128348B1 publication Critical patent/FR2128348B1/fr

Status Granted legal-status Critical Current

Links

DTUNAUYGSZGOFG-UHFFFAOYSA-N 1H-thieno[3,2-d]pyrimidine-2-thione Chemical compound N1C(=S)N=CC2=C1C=CS2 DTUNAUYGSZGOFG-UHFFFAOYSA-N 0.000 title 1
230000000954 anitussive effect Effects 0.000 title 1
229940124584 antitussives Drugs 0.000 title 1
ZZVUWRFHKOJYTH-UHFFFAOYSA-N diphenhydramine Chemical compound C=1C=CC=CC=1C(OCCN(C)C)C1=CC=CC=C1 ZZVUWRFHKOJYTH-UHFFFAOYSA-N 0.000 title 1
230000000871 hypocholesterolemic effect Effects 0.000 title 1
239000000932 sedative agent Substances 0.000 title 1
230000001624 sedative effect Effects 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 4
UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 abstract 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
229940100198 alkylating agent Drugs 0.000 abstract 1
239000002168 alkylating agent Substances 0.000 abstract 1
125000005336 allyloxy group Chemical group 0.000 abstract 1
SOIFLUNRINLCBN-UHFFFAOYSA-N ammonium thiocyanate Chemical compound [NH4+].[S-]C#N SOIFLUNRINLCBN-UHFFFAOYSA-N 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

FR7206053A 1971-03-08 1972-02-23 Mercapto-thienopyrimidine derivs - with sedative antitussive and hypocholesterolaemic activity Granted FR2128348A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
AT195571A AT303046B (de)	1971-03-08	1971-03-08	Verfahren zur Herstellung von neuen 2-Mercapto-3,4-dihydro-thieno[2,3-d]pyrimidin-4-on-Derivaten und von deren Metallsalzen

Publications (2)

Publication Number	Publication Date
FR2128348A1 true FR2128348A1 (en)	1972-10-20
FR2128348B1 FR2128348B1 (fr)	1975-10-10

Family

ID=3524652

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR7206053A Granted FR2128348A1 (en)	1971-03-08	1972-02-23	Mercapto-thienopyrimidine derivs - with sedative antitussive and hypocholesterolaemic activity

Country Status (3)

Country	Link
AT (1)	AT303046B (fr)
DE (1)	DE2210503A1 (fr)
FR (1)	FR2128348A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE793423A (fr) *	1972-01-04	1973-04-16	Centre Etd Ind Pharma	Derives thiazoliques, leur procede de preparation et leurs application
JP4010563B2 (ja) *	1995-07-05	2007-11-21	イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー	殺菌・殺カビ性のピリミジノン類

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2079314A1 (en) *	1970-02-09	1971-11-12	Centre Etd Ind Pharma	2, 4-dioxo-1, 2, 3, 4, 5, 6, 7, 8-octahydrobenzothieno - (2, 3-d) pyrimidines - with antiinflammatory, analgesic, antitussive
FR2081496A1 (en) *	1970-02-09	1971-12-03	Centre Etd Ind Pharma	Antiinflammatory and analgesic benzo-thieno-pyrimidine - deriv

1971
- 1971-03-08 AT AT195571A patent/AT303046B/de not_active IP Right Cessation
1972
- 1972-02-23 FR FR7206053A patent/FR2128348A1/fr active Granted
- 1972-03-04 DE DE19722210503 patent/DE2210503A1/de active Pending

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2079314A1 (en) *	1970-02-09	1971-11-12	Centre Etd Ind Pharma	2, 4-dioxo-1, 2, 3, 4, 5, 6, 7, 8-octahydrobenzothieno - (2, 3-d) pyrimidines - with antiinflammatory, analgesic, antitussive
FR2081496A1 (en) *	1970-02-09	1971-12-03	Centre Etd Ind Pharma	Antiinflammatory and analgesic benzo-thieno-pyrimidine - deriv

Also Published As

Publication number	Publication date
DE2210503A1 (de)	1972-09-21
FR2128348B1 (fr)	1975-10-10
AT303046B (de)	1972-11-10

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Legal Events

Date	Code	Title	Description
1985-12-20	ST	Notification of lapse