FR2158796A5 - 1-oxa-2-oxo-3, 8-diaza-8-phenethyl-spiro (4, 5)-decane prepn - - starting from 1-phenethyl-4-piperidinone - Google Patents

1-oxa-2-oxo-3, 8-diaza-8-phenethyl-spiro (4, 5)-decane prepn - - starting from 1-phenethyl-4-piperidinone

Info

Publication number: FR2158796A5
Authority: FR; France
Prior art keywords: phenethyl; piperidinone; prepn; diaza; oxa
Prior art date: 1971-09-07
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

FR7226755A

Other languages

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Buskine SA

Original Assignee

Buskine SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-09-07

Filing date

1972-07-25

Publication date

1973-06-15

1972-07-25 Application filed by Buskine SA filed Critical Buskine SA

1973-06-15 Application granted granted Critical

1973-06-15 Publication of FR2158796A5 publication Critical patent/FR2158796A5/fr

Status Expired legal-status Critical Current

Links

YDJXNYNKKXZBMP-UHFFFAOYSA-N n-phenethyl-4-piperidinone Chemical compound C1CC(=O)CCN1CCC1=CC=CC=C1 YDJXNYNKKXZBMP-UHFFFAOYSA-N 0.000 title abstract 2
FVNFBBAOMBJTST-UHFFFAOYSA-N 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one Chemical compound O1C(=O)NCC11CCN(CCC=2C=CC=CC=2)CC1 FVNFBBAOMBJTST-UHFFFAOYSA-N 0.000 title 1
NWZSZGALRFJKBT-KNIFDHDWSA-N (2s)-2,6-diaminohexanoic acid;(2s)-2-hydroxybutanedioic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O.NCCCC[C@H](N)C(O)=O NWZSZGALRFJKBT-KNIFDHDWSA-N 0.000 abstract 1
OMNRFKVAOXLLMC-UHFFFAOYSA-N 2-[4-hydroxy-1-(1-phenylethyl)piperidin-4-yl]acetohydrazide Chemical compound C1(=CC=CC=C1)C(C)N1CCC(CC1)(CC(=O)NN)O OMNRFKVAOXLLMC-UHFFFAOYSA-N 0.000 abstract 1
IOVCWXUNBOPUCH-UHFFFAOYSA-N Nitrous acid Chemical compound ON=O IOVCWXUNBOPUCH-UHFFFAOYSA-N 0.000 abstract 1
238000006680 Reformatsky reaction Methods 0.000 abstract 1
QVKVZYNSQGGYJO-UHFFFAOYSA-N ethyl 2-[4-hydroxy-1-(1-phenylethyl)piperidin-4-yl]acetate Chemical compound C1(=CC=CC=C1)C(C)N1CCC(CC1)(CC(=O)OCC)O QVKVZYNSQGGYJO-UHFFFAOYSA-N 0.000 abstract 1
PQJJJMRNHATNKG-UHFFFAOYSA-N ethyl bromoacetate Chemical compound CCOC(=O)CBr PQJJJMRNHATNKG-UHFFFAOYSA-N 0.000 abstract 1
IKDUDTNKRLTJSI-UHFFFAOYSA-N hydrazine monohydrate Substances O.NN IKDUDTNKRLTJSI-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/48—Oxygen atoms attached in position 4 having an acyclic carbon atom attached in position 4

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

FR7226755A 1971-09-07 1972-07-25 1-oxa-2-oxo-3, 8-diaza-8-phenethyl-spiro (4, 5)-decane prepn - - starting from 1-phenethyl-4-piperidinone Expired FR2158796A5 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH1314171A CH536314A (fr)	1971-09-07	1971-09-07	Procédé de synthèse du oxa-1, oxo-2, diaza-3,8, phénéthyl-8, spiro(4,5)-décane

Publications (1)

Publication Number	Publication Date
FR2158796A5 true FR2158796A5 (en)	1973-06-15

Family

ID=4389675

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR7226755A Expired FR2158796A5 (en)	1971-09-07	1972-07-25	1-oxa-2-oxo-3, 8-diaza-8-phenethyl-spiro (4, 5)-decane prepn - - starting from 1-phenethyl-4-piperidinone

Country Status (12)

Country	Link
AR (1)	AR204072A1 (fr)
AT (1)	AT319942B (fr)
BE (1)	BE774170A (fr)
BR (1)	BR7204892D0 (fr)
CA (1)	CA1011737A (fr)
CH (1)	CH536314A (fr)
DE (2)	DE2242387A1 (fr)
ES (1)	ES396186A1 (fr)
FR (1)	FR2158796A5 (fr)
HU (1)	HU166971B (fr)
NL (1)	NL7210183A (fr)
ZA (1)	ZA724587B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2498599A1 (fr) *	1981-01-28	1982-07-30	Sandoz Sa	Nouvelles 4-aminomethylpolyalkylpiperidines utilisables comme stabilisants de polymeres et leur preparation

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4248877A (en)	1973-06-22	1981-02-03	Sandoz Ltd.	Organic compounds
US4558049A (en) *	1982-11-24	1985-12-10	Farmitalia Carlo Erba S.P.A.	Antipsycotic benzoxazines
DE10132746A1 (de) *	2001-07-05	2003-02-06	Gruenenthal Gmbh	Substituierte 1-Phenethylpiperidinverbindungen
CN111484507B (zh) *	2019-01-29	2022-05-17	南京药石科技股份有限公司	一种氧氮杂螺环类化合物的制备方法

1971
- 1971-09-07 CH CH1314171A patent/CH536314A/fr not_active IP Right Cessation
- 1971-10-19 BE BE774170A patent/BE774170A/fr unknown
- 1971-10-20 ES ES396186A patent/ES396186A1/es not_active Expired
1972
- 1972-01-01 AR AR243173A patent/AR204072A1/es active
- 1972-07-04 CA CA146,291A patent/CA1011737A/en not_active Expired
- 1972-07-04 ZA ZA724587A patent/ZA724587B/xx unknown
- 1972-07-21 BR BR004892/72A patent/BR7204892D0/pt unknown
- 1972-07-24 NL NL7210183A patent/NL7210183A/xx not_active Application Discontinuation
- 1972-07-25 FR FR7226755A patent/FR2158796A5/fr not_active Expired
- 1972-07-28 AT AT650672A patent/AT319942B/de not_active IP Right Cessation
- 1972-08-29 DE DE2242387A patent/DE2242387A1/de active Pending
- 1972-08-29 DE DE19722265193 patent/DE2265193A1/de active Pending
- 1972-09-06 HU HUBU624A patent/HU166971B/hu unknown

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2498599A1 (fr) *	1981-01-28	1982-07-30	Sandoz Sa	Nouvelles 4-aminomethylpolyalkylpiperidines utilisables comme stabilisants de polymeres et leur preparation

Also Published As

Publication number	Publication date
CA1011737A (en)	1977-06-07
CH536314A (fr)	1973-04-30
BR7204892D0 (pt)	1973-07-26
AT319942B (de)	1975-01-10
ZA724587B (en)	1973-04-25
AR204072A1 (es)	1975-11-20
DE2242387A1 (de)	1973-03-15
ES396186A1 (es)	1974-04-16
DE2265193A1 (de)	1976-12-30
AU4427972A (en)	1974-01-10
HU166971B (fr)	1975-07-28
NL7210183A (fr)	1973-03-09
BE774170A (fr)	1972-02-14

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Legal Events

Date	Code	Title	Description
1983-05-20	ST	Notification of lapse