FR2289487A2 - Procede de recuperation de phenylalcoylamines optiquement actives en vue de leur transformation en leurs enanthiomorphes - Google Patents

Procede de recuperation de phenylalcoylamines optiquement actives en vue de leur transformation en leurs enanthiomorphes

Info

Publication number: FR2289487A2
Authority: FR; France
Prior art keywords: reaction; oxidising; ketone; racemising; aminopropanes
Prior art date: 1974-10-31
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

FR7436361A

Other languages

English (en)

Other versions

FR2289487B2 (fr

Inventor

Henry Najer

Yves Robert Alain Pascal

Regis Dupont

Don Pierre Rene Luc Giudicelli

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Synthelabo SA

Original Assignee

Synthelabo SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-10-31

Filing date

1974-10-31

Publication date

1976-05-28

1973-05-18 Priority to DE19732325328 priority Critical patent/DE2325328C3/de

1974-10-31 Application filed by Synthelabo SA filed Critical Synthelabo SA

1974-10-31 Priority to FR7436361A priority patent/FR2289487A2/fr

1974-11-26 Priority to IE2419/14A priority patent/IE40218B1/xx

1974-11-26 Priority to DE19742455914 priority patent/DE2455914C3/de

1974-11-27 Priority to NL7415466A priority patent/NL7415466A/xx

1974-11-27 Priority to DK616474A priority patent/DK616474A/da

1974-11-27 Priority to AU75795/74A priority patent/AU492268B2/en

1974-11-28 Priority to LU71383A priority patent/LU71383A1/xx

1974-11-28 Priority to AT952574A priority patent/AT335421B/de

1974-11-28 Priority to CA214,853A priority patent/CA1038406A/fr

1974-11-28 Priority to NO744291A priority patent/NO744291L/no

1974-11-28 Priority to SE7414938A priority patent/SE7414938L/xx

1974-11-29 Priority to CH1588674A priority patent/CH603544A5/xx

1974-11-29 Priority to GB5182874A priority patent/GB1470110A/en

1974-11-29 Priority to JP13761874A priority patent/JPS5331136B2/ja

1976-05-28 Publication of FR2289487A2 publication Critical patent/FR2289487A2/fr

1979-02-09 Application granted granted Critical

1979-02-09 Publication of FR2289487B2 publication Critical patent/FR2289487B2/fr

Status Granted legal-status Critical Current

Links

JRNVZBWKYDBUCA-UHFFFAOYSA-N N-chlorosuccinimide Chemical compound ClN1C(=O)CCC1=O JRNVZBWKYDBUCA-UHFFFAOYSA-N 0.000 title abstract 4
238000006243 chemical reaction Methods 0.000 title abstract 4
150000002576 ketones Chemical class 0.000 title abstract 3
KWTSXDURSIMDCE-UHFFFAOYSA-N 1-phenylpropan-2-amine Chemical class CC(N)CC1=CC=CC=C1 KWTSXDURSIMDCE-UHFFFAOYSA-N 0.000 title 1
150000001412 amines Chemical class 0.000 title 1
-1 CF3S Chemical group 0.000 abstract 1
239000003513 alkali Substances 0.000 abstract 1
150000004703 alkoxides Chemical class 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
230000003287 optical effect Effects 0.000 abstract 1
230000020477 pH reduction Effects 0.000 abstract 1
125000003884 phenylalkyl group Chemical group 0.000 abstract 1
239000002798 polar solvent Substances 0.000 abstract 1
238000010992 reflux Methods 0.000 abstract 1
125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

FR7436361A 1972-05-31 1974-10-31 Procede de recuperation de phenylalcoylamines optiquement actives en vue de leur transformation en leurs enanthiomorphes Granted FR2289487A2 (fr)

Priority Applications (15)

Application Number	Priority Date	Filing Date	Title
DE19732325328 DE2325328C3 (de)	1972-05-31	1973-05-18	Phenyläthylaminderivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel
FR7436361A FR2289487A2 (fr)	1974-10-31	1974-10-31	Procede de recuperation de phenylalcoylamines optiquement actives en vue de leur transformation en leurs enanthiomorphes
IE2419/14A IE40218B1 (en)	1973-11-29	1974-11-26	Process for recovering phenylalkylamines
DE19742455914 DE2455914C3 (de)	1973-11-29	1974-11-26	Verfahren zur Herstellung von racemischen Phenylpropylaminen
DK616474A DK616474A (fr)	1973-11-29	1974-11-27
AU75795/74A AU492268B2 (en)	1973-11-29	1974-11-27	Process for recovering phenylalkylamines
NL7415466A NL7415466A (nl)	1973-11-29	1974-11-27	Werkwijze voor het winnen van fenylalkylaminen.
AT952574A AT335421B (de)	1973-11-29	1974-11-28	Verfahren zur herstellung von racemischen phenylalkylaminen
LU71383A LU71383A1 (fr)	1973-11-29	1974-11-28
CA214,853A CA1038406A (fr)	1973-11-29	1974-11-28	Procede de recuperation de phenylalkylamines
NO744291A NO744291L (fr)	1973-11-29	1974-11-28
SE7414938A SE7414938L (fr)	1973-11-29	1974-11-28
CH1588674A CH603544A5 (fr)	1973-11-29	1974-11-29
GB5182874A GB1470110A (en)	1973-11-29	1974-11-29	Process for recovering phenylalkylamines
JP13761874A JPS5331136B2 (fr)	1973-11-29	1974-11-29

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR7436361A FR2289487A2 (fr)	1974-10-31	1974-10-31	Procede de recuperation de phenylalcoylamines optiquement actives en vue de leur transformation en leurs enanthiomorphes

Publications (2)

Publication Number	Publication Date
FR2289487A2 true FR2289487A2 (fr)	1976-05-28
FR2289487B2 FR2289487B2 (fr)	1979-02-09

Family

ID=9144573

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FR7436361A Granted FR2289487A2 (fr)	1972-05-31	1974-10-31	Procede de recuperation de phenylalcoylamines optiquement actives en vue de leur transformation en leurs enanthiomorphes

Country Status (1)

Country	Link
FR (1)	FR2289487A2 (fr)

1974
- 1974-10-31 FR FR7436361A patent/FR2289487A2/fr active Granted

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Also Published As

Publication number	Publication date
FR2289487B2 (fr)	1979-02-09

Similar Documents

Publication	Publication Date	Title
GB1040723A (en)	1966-09-01	Process for the preparation of new amino ketones
DK179681A (da)	1981-10-24	Fremgangsmaade til fremstilling af acylcyanider
FR2289487A2 (fr)	1976-05-28	Procede de recuperation de phenylalcoylamines optiquement actives en vue de leur transformation en leurs enanthiomorphes
FR2253014A1 (en)	1975-06-27	Racemising 1-phenyl-2-aminopropanes - by oxidising to ketone with N-chloro succinimide then reaction with amine
ATE54913T1 (de)	1990-08-15	Industrielle verbindungen anwendbar als zwischenprodukte in der herstellung von in stellung 2 substituierten 4-hydroxy 3quinolincarboxamid-derivaten und die herstellung von diesen zwischenprodukten.
DK185789D0 (da)	1989-04-18	Fremgangsmaade til fremstilling af optisk aktive 3-(carbonhydridsulfonyloxy)thiolaner eller deres 1-oxider og mellemprodukter ved fremgangsmaaden
ES8800193A1 (es)	1987-10-16	Procedimiento para preparar 2,4-difenil-1,3-dioxanos
FR2155856A1 (en)	1973-05-25	N-2 pyridylureas - with antiinflammatory and analgesic activity
DK552682A (da)	1983-06-15	Fremgangsmaade til fremstilling af hydroxybenzylaminobenzener
ES337227A1 (es)	1968-02-16	Procedimiento para la obtencion de derivados de alqueno.
SE7904396L (sv)	1979-11-24	Sett att framstella arylettiksyraderivat
FR2168136A1 (en)	1973-08-31	2-aminobenzoyl hydrazones - with antiinflammatory, analgesic and antipyretic activity
FR2042302A1 (en)	1971-02-12	Therapeutic indole derivs. prodn.
FR2094501A5 (en)	1972-02-04	3-salicyloyloxy derivatives of phenylbutazone - and analogues - with antiinflammatory antipyretic, analgesic, antirhe
ES395164A1 (es)	1974-11-16	Un procedimiento de preparacion de un nuevo compuesto de difenil-sulfona.
FR2121033A5 (en)	1972-08-18	Pyrimidine 5-carboxylic acid esters - from polychloroalkylimide acid chlorides and beta-aminoacrylic acid esters, plant protec
FR2268779A1 (en)	1975-11-21	Trimethyl-para-benzoquinone prepn. - by oxidn. of 2,3,5-trimethyl-phenol in presence of complex salts of cobalt and Schiff's bases
GB1197251A (en)	1970-07-01	N-Phenyl p-Chlorobenzamide Derivatives and their Conversion to Indolyl Acetic Acid Derivatives
FR2130974A5 (en)	1972-11-10	4-(5-thiazolecarbonyl)-2-phenyl-(3-alkyl)-morpholines - - useful as hypocholesterolemics and anorexigenics
GB1353133A (en)	1974-05-15	Bisstyryltriazoles their use for the optical brightening of organic materials and process for their manufacture
FR1417723A (fr)	1965-11-12	Procédé d'oxydation microbiologique de composés organiques
FR2197570A1 (en)	1974-03-29	Esters of penicillins with hydroxychalcones - with higher antibacterial activity than the parent penicillins
FR2229399A2 (en)	1974-12-13	2-(3-Chloro-4-(4-tetrahydropyranyl) phenyl)propionic acid - and esters with analgesic and antiflammatory activity
FR2081319A1 (en)	1971-12-03	Alpha-iminobenzyl penicillins - by direct reaction of aldehydes with unisolated derivs of alpha aminobenzylpenicillin
US2802834A (en)	1957-08-13	3-tetrahydrofurfuryloxyphthalide