FR2290907A2 - Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent - Google Patents

Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent

Info

Publication number
FR2290907A2
FR2290907A2 FR7437295A FR7437295A FR2290907A2 FR 2290907 A2 FR2290907 A2 FR 2290907A2 FR 7437295 A FR7437295 A FR 7437295A FR 7437295 A FR7437295 A FR 7437295A FR 2290907 A2 FR2290907 A2 FR 2290907A2
Authority
FR
France
Prior art keywords
alkyl
hydroxyethylpiperidino
phenothiazines
antiemetic activity
antiemetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7437295A
Other languages
English (en)
Other versions
FR2290907B2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Priority to FR7437295A priority Critical patent/FR2290907A2/fr
Priority to AR260778A priority patent/AR207789A1/es
Priority to AR257380A priority patent/AR205635A1/es
Priority to AR260779A priority patent/AR206441A1/es
Priority to NL7500421.A priority patent/NL165739C/xx
Priority to HURO818A priority patent/HU168855B/hu
Priority to CS75418A priority patent/CS187458B2/cs
Priority to CA218,368A priority patent/CA1021337A/fr
Priority to CH70975A priority patent/CH602718A5/xx
Priority to US05/542,799 priority patent/US3961055A/en
Priority to JP839775A priority patent/JPS541313B2/ja
Priority to IE109/75A priority patent/IE40364B1/xx
Priority to SU7502101069A priority patent/SU577994A3/ru
Priority to CH1069577A priority patent/CH599955A5/xx
Priority to IL7546484A priority patent/IL46484A/en
Priority to NO750182A priority patent/NO750182L/no
Priority to DK17275*#A priority patent/DK17275A/da
Priority to CH1069477A priority patent/CH602720A5/xx
Priority to GB259975A priority patent/GB1460427A/en
Priority to AU77487/75A priority patent/AU470810B2/en
Priority to LU71688*A priority patent/LU71688A1/xx
Priority to SE7500642A priority patent/SE414028B/xx
Priority to DE2502504A priority patent/DE2502504C3/de
Priority to AT46475A priority patent/AT338816B/de
Priority to ES434026A priority patent/ES434026A1/es
Priority to FI750160A priority patent/FI57948C/fi
Priority to ES439072A priority patent/ES439072A1/es
Priority to ES439073A priority patent/ES439073A1/es
Publication of FR2290907A2 publication Critical patent/FR2290907A2/fr
Priority to CS773616A priority patent/CS187499B2/cs
Priority to CS773617A priority patent/CS187500B2/cs
Priority to SE7709432A priority patent/SE414029B/xx
Priority to JP6008178A priority patent/JPS54109988A/ja
Application granted granted Critical
Publication of FR2290907B2 publication Critical patent/FR2290907B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
    • C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FR7437295A 1974-01-22 1974-11-12 Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent Granted FR2290907A2 (fr)

Priority Applications (32)

Application Number Priority Date Filing Date Title
FR7437295A FR2290907A2 (fr) 1974-11-12 1974-11-12 Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent
AR260778A AR207789A1 (es) 1974-01-22 1975-01-01 Procedimiento para preparar nuevos esteres derivados de 2-hidroxi-2-dimetilsulfamoil-6-(((hidroxi-2-etil)-4-pipedidino)-3-propil)-10-fenotiazina
AR257380A AR205635A1 (es) 1974-01-22 1975-01-01 Procedimiento para preparar nuevos derivados de la (((hidroxi-2 etil)-4-piperidino) -3 propil) -10 fenotiazina
AR260779A AR206441A1 (es) 1974-11-12 1975-01-01 Procedimiento para preparar hidroxi-2-dimetilsulfamoil-6(hidroxietil-4 piperidino)-3-propil)-10-fenotiazina
NL7500421.A NL165739C (nl) 1974-01-22 1975-01-14 Werkwijze ter bereiding van farmaceutische preparaten met antiemetische werking, die fenothiazinederivaten bevatten, verkregen gevormde preparaten en werkwijze ter bereiding van de nieuwe fenothiazinederivaten.
HURO818A HU168855B (fr) 1974-01-22 1975-01-20
SE7500642A SE414028B (sv) 1974-01-22 1975-01-21 Forfarande for framstellning av terapeutisk verksamma fentiazinderivat
CH70975A CH602718A5 (fr) 1974-01-22 1975-01-21
US05/542,799 US3961055A (en) 1974-01-22 1975-01-21 Hydroxy and ether containing phenothiazine derivatives
JP839775A JPS541313B2 (fr) 1974-01-22 1975-01-21
IE109/75A IE40364B1 (en) 1974-01-22 1975-01-21 New phenothiazine derivatives
SU7502101069A SU577994A3 (ru) 1974-01-22 1975-01-21 Способ получени производных фенотиазина или их солей
CH1069577A CH599955A5 (fr) 1974-11-12 1975-01-21
IL7546484A IL46484A (en) 1974-01-22 1975-01-21 2-hydroxy-10-(3-(4-(2-hydroxyethyl)-piperidino)propyl)-phenothiazine derivatives processes for the preparation thereof and pharmaceutical compositions containing the same
NO750182A NO750182L (fr) 1974-01-22 1975-01-21
DK17275*#A DK17275A (fr) 1974-01-22 1975-01-21
CS75418A CS187458B2 (en) 1974-01-22 1975-01-21 Process for preparing new derivatives of phenothiazine
GB259975A GB1460427A (en) 1974-01-22 1975-01-21 Phenothiazine derivatives
AU77487/75A AU470810B2 (en) 1974-01-22 1975-01-21 New phenothiazine derivatives
LU71688*A LU71688A1 (fr) 1974-01-22 1975-01-21
CA218,368A CA1021337A (fr) 1974-01-22 1975-01-21 Derives de la phenothiazine, leur preparation et les compositions qui les contiennent
CH1069477A CH602720A5 (fr) 1974-01-22 1975-01-21
AT46475A AT338816B (de) 1974-01-22 1975-01-22 Verfahren zur herstellung von neuen phenthiazinderivaten und von ihren saureadditionssalzen
ES434026A ES434026A1 (es) 1974-01-22 1975-01-22 Procedimiento para preparar derivados de la fenotiazina.
FI750160A FI57948C (fi) 1974-01-22 1975-01-22 Foerfarande foer framstaellning av antiemetiska 10-(3-(4-(2-hydroxietyl)piperidino)propyl)fenotiaziner
DE2502504A DE2502504C3 (de) 1974-01-22 1975-01-22 Phenothiazinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
ES439073A ES439073A1 (es) 1974-11-12 1975-07-02 Procedimiento para preparar derivados de la fenotiazina.
ES439072A ES439072A1 (es) 1974-01-22 1975-07-02 Procedimiento para preparar derivados de la fenotiazina.
CS773616A CS187499B2 (en) 1974-01-22 1977-06-01 Process for preparing new derivatives of phenothiazine
CS773617A CS187500B2 (en) 1974-11-12 1977-06-01 Process for preparing new derivatives of phenothiazine
SE7709432A SE414029B (sv) 1974-01-22 1977-08-22 Forfarande for framstellning av terapeutiskt aktiva fentiazinderivat
JP6008178A JPS54109988A (en) 1974-11-12 1978-05-22 Manufacture of novel phenothiazine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7437295A FR2290907A2 (fr) 1974-11-12 1974-11-12 Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent

Publications (2)

Publication Number Publication Date
FR2290907A2 true FR2290907A2 (fr) 1976-06-11
FR2290907B2 FR2290907B2 (fr) 1978-08-18

Family

ID=9144859

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7437295A Granted FR2290907A2 (fr) 1974-01-22 1974-11-12 Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent

Country Status (5)

Country Link
JP (1) JPS54109988A (fr)
AR (1) AR206441A1 (fr)
CH (1) CH599955A5 (fr)
ES (1) ES439073A1 (fr)
FR (1) FR2290907A2 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1212031A (fr) * 1957-10-21 1960-03-21 Rhone Poulenc Sa Dérivés de la phénothiazine substitués à l'azote par une chaîne basique comportant un hétérocycle et leur préparation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1212031A (fr) * 1957-10-21 1960-03-21 Rhone Poulenc Sa Dérivés de la phénothiazine substitués à l'azote par une chaîne basique comportant un hétérocycle et leur préparation

Also Published As

Publication number Publication date
JPS54109988A (en) 1979-08-29
FR2290907B2 (fr) 1978-08-18
ES439073A1 (es) 1977-03-01
CH599955A5 (fr) 1978-06-15
AR206441A1 (es) 1976-07-23

Similar Documents

Publication Publication Date Title
ES503768A0 (es) Procedimiento de preparacion de derivados de 1-fenil-1-hi- droxi-etilamina
SE7604376L (sv) Forsterkare lemplig for anvendning sasom ett drivorgan for fergbildror
ES418924A1 (es) Procedimiento para la obtencion de 13, 14-dihidroprosta- glandinas.
IT1057845B (it) Endoprotesi per un articolazione del corpo umano
BE843536A (fr) Produits antisolaires pour l'usage corporel
SE7710114L (sv) 7-acylamino-8-oxo-3-oxa-1-azabicyklo(4.2.0)oktan-2-karbonsyraderivat
FR2258186A1 (en) 10-((4-hydroxyethylpiperidino)alkyl)-phenothiazines - with antiemetic activity
FR2290907A2 (fr) Nouveaux derives de la phenothiazine, leur preparation et les compositions qui les contiennent
ES393986A1 (es) Un procedimiento para la preparacion de derivados de alco- hol 3,4-dihidroxibencilico.
FR2422651A1 (fr) Derives de pyrrolidinecarboxaldehyde et de piperidinecarboxaldehyde a usage therapeutique
ES434026A1 (es) Procedimiento para preparar derivados de la fenotiazina.
DE3368609D1 (en) Carbacyclines, process for their preparation and their use as medicines
FR2430946A1 (fr) Derives imidazolylethoxyles de pyrazolo (3,4-b)-pyridine-5-methanols, a action antifongique et antibacterienne
FR2427094B1 (fr) Medicament constitue par un derive de cyclopentyl-aldehyde et composition le renfermant
FR2286132A1 (fr) Preparation d'un derive de 2-aminopyrroline
ES452174A1 (es) Procedimiento de preparacion de 2,9-dioxatriciclo (4,3,1, 03,7) decanos.
ES461779A1 (es) Procedimiento para la preparacion de lariloxi-3-amino-3-pro-panoles.
ES434827A1 (es) Procedimiento para la preparacion de derivados aminicos de los azidofenoles.
GB1223635A (en) Substituted cysteamines of use in anti-seborrhoeic compositions
ES449895A1 (es) Procedimiento para preparar alcoxiacilaminofenilacetamidas.
ES401174A1 (es) Procedimiento para la preparacion de nuevos esteres alcohi-licos del acido tiolcarbamidico basicamente sustituidos.
GB1530848A (en) 2-(phenylalkylhydrazono)-propionic acid derivatives
FR2281363A1 (fr) Composes pesticides
NL7414311A (en) Promoting hair growth with prepn contg urea (deriv) - applied externally, avoiding difficulties of oral medication
ES424787A1 (es) Un procedimiento para la preparacion de 4,5-dialquil-6,7- benzomorfano.