FR2360603A1 - Nouveaux derives semi-synthetiques de l'oleandomycine modifies en position 8 - Google Patents

Nouveaux derives semi-synthetiques de l'oleandomycine modifies en position 8

Info

Publication number
FR2360603A1
FR2360603A1 FR7724261A FR7724261A FR2360603A1 FR 2360603 A1 FR2360603 A1 FR 2360603A1 FR 7724261 A FR7724261 A FR 7724261A FR 7724261 A FR7724261 A FR 7724261A FR 2360603 A1 FR2360603 A1 FR 2360603A1
Authority
FR
France
Prior art keywords
oleandomycin
modified
new semi
synthetic derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7724261A
Other languages
English (en)
Other versions
FR2360603B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of FR2360603A1 publication Critical patent/FR2360603A1/fr
Application granted granted Critical
Publication of FR2360603B1 publication Critical patent/FR2360603B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Nouveaux dérivés d'oléandomycine semi-synthétiques, présentant des modifications sur l'atome de carbone en position 8. On obtient ces composés par contact d'une oléandomycine ou de ses dérivés avec un amalgame métallique dans un solvant non aprotique en mélange avec un solvant inerte vis-à-vis de la réaction. Les nouveaux composés de l'invention sont doués de propriétés antibactériennes.
FR7724261A 1976-08-06 1977-08-05 Nouveaux derives semi-synthetiques de l'oleandomycine modifies en position 8 Granted FR2360603A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/712,360 US4036853A (en) 1976-08-06 1976-08-06 Semi-synthetic oleandomycin derivatives-C8 modifications

Publications (2)

Publication Number Publication Date
FR2360603A1 true FR2360603A1 (fr) 1978-03-03
FR2360603B1 FR2360603B1 (fr) 1980-03-21

Family

ID=24861786

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7724261A Granted FR2360603A1 (fr) 1976-08-06 1977-08-05 Nouveaux derives semi-synthetiques de l'oleandomycine modifies en position 8

Country Status (12)

Country Link
US (3) US4036853A (fr)
JP (1) JPS5321185A (fr)
AR (3) AR217652A1 (fr)
BE (1) BE857536A (fr)
DE (1) DE2733867C3 (fr)
DK (1) DK148281C (fr)
ES (1) ES461210A1 (fr)
FR (1) FR2360603A1 (fr)
GB (1) GB1530569A (fr)
IE (1) IE45964B1 (fr)
LU (1) LU77939A1 (fr)
NL (1) NL173273C (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4125705A (en) * 1977-02-04 1978-11-14 Pfizer Inc. Semi-synthetic 4-amino-oleandomycin derivatives
US4085119A (en) * 1977-02-04 1978-04-18 Pfizer Inc. 4-Substituted amino derivatives of oleandomycin
US4090017A (en) * 1977-02-04 1978-05-16 Pfizer Inc. 4-Deoxy-4-substituted amino derivatives of oleandomycin
US4098993A (en) * 1977-07-25 1978-07-04 Pfizer Inc. Semi-synthetic 4-ureido-oleandomycin derivatives
US4098994A (en) * 1977-09-15 1978-07-04 Pfizer Inc. Sulfamide derivatives of 4 -deoxy-oleandomycin
US4438109A (en) 1980-07-25 1984-03-20 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Tylosin derivatives
IT1169013B (it) 1981-01-09 1987-05-20 Pierrel Spa Composti macrolidici ad attivita' antibiotica, procedimento e microorganismo per la loro preparazione e relative composizioni farmaceutiche
AU551142B2 (en) * 1981-07-09 1986-04-17 Zaidan Hojin Biseibutsu Kagaku Kenkyukai Tylosin derivatives
US4474768A (en) * 1982-07-19 1984-10-02 Pfizer Inc. N-Methyl 11-aza-10-deoxo-10-dihydro-erytromycin A, intermediates therefor

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3022219A (en) * 1958-03-07 1962-02-20 Pfizer & Co C Acyl esters of oleandomycin
US3179652A (en) * 1961-09-05 1965-04-20 Pfizer & Co C Antibiotic recovery process and salts produced thereby
US3144466A (en) * 1963-03-08 1964-08-11 Pfizer & Co C Diacyl esters of de-oleandrosehydroxyoleandomycin and process therefor

Also Published As

Publication number Publication date
DK148281B (da) 1985-05-28
IE45964B1 (en) 1983-01-12
NL173273B (nl) 1983-08-01
DK148281C (da) 1985-11-11
DE2733867B2 (de) 1980-10-30
FR2360603B1 (fr) 1980-03-21
DK343877A (da) 1978-02-07
US4110531A (en) 1978-08-29
AR217664A1 (es) 1980-04-15
US4110530A (en) 1978-08-29
ES461210A1 (es) 1978-08-16
JPS5321185A (en) 1978-02-27
NL173273C (nl) 1984-01-02
US4036853A (en) 1977-07-19
JPS552438B2 (fr) 1980-01-19
BE857536A (fr) 1978-02-06
NL7708427A (nl) 1978-02-08
LU77939A1 (fr) 1979-05-23
IE45964L (en) 1978-02-06
AR217652A1 (es) 1980-04-15
GB1530569A (en) 1978-11-01
AR220904A1 (es) 1980-12-15
DE2733867C3 (de) 1981-08-27
DE2733867A1 (de) 1978-02-09

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