FR2372628A2 - Nouveaux derives de 5-thiazol methane amine, un procede pour leur preparation, leur application a titre de medicaments - Google Patents

Nouveaux derives de 5-thiazol methane amine, un procede pour leur preparation, leur application a titre de medicaments

Info

Publication number
FR2372628A2
FR2372628A2 FR7609337A FR7609337A FR2372628A2 FR 2372628 A2 FR2372628 A2 FR 2372628A2 FR 7609337 A FR7609337 A FR 7609337A FR 7609337 A FR7609337 A FR 7609337A FR 2372628 A2 FR2372628 A2 FR 2372628A2
Authority
FR
France
Prior art keywords
alkyl
methyl
thiazole
antilipolytic
amines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7609337A
Other languages
English (en)
Other versions
FR2372628B2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7609337A priority Critical patent/FR2372628A2/fr
Priority to SE7609666A priority patent/SE7609666L/xx
Priority to US05/721,370 priority patent/US4108994A/en
Priority to JP51107981A priority patent/JPS5236664A/ja
Priority to NL7610062A priority patent/NL7610062A/xx
Priority to CH1157176A priority patent/CH613958A5/fr
Priority to AU17630/76A priority patent/AU499425B2/en
Priority to CA261,119A priority patent/CA1082716A/fr
Priority to DK408176A priority patent/DK408176A/da
Priority to LU75764A priority patent/LU75764A1/xx
Priority to ES451466A priority patent/ES451466A1/es
Priority to IE2042/76A priority patent/IE44294B1/en
Priority to DE19762641129 priority patent/DE2641129A1/de
Priority to GB37770/76A priority patent/GB1526038A/en
Publication of FR2372628A2 publication Critical patent/FR2372628A2/fr
Application granted granted Critical
Publication of FR2372628B2 publication Critical patent/FR2372628B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'addition a pour objet les produits de formule I du brevet principal, ainsi que les sels de produits de formule I du brevet principal dont les noms suivent : - la 2-n-propyl 5-thiazol méthane amine et son hémisuccinate, - le 2-méthyl 5-(pipéridin-l-yl-méthyl) thiazole et son hémiéthanedisulfonate, - le 2-méthyl 5-(4-méthyl pipérazin- l-yl-méthyl) thiazole, produits qui constituent, comme les produits du brevet principal, des médicaments utiles en thérapeutique, notamment comme hypolipémiants. La presente addition a également pour objet un nouveau procédé de préparation des produits de formule I du brevet principal dans laquelle R2 et R3 représentent un atome d'hydrogène.
FR7609337A 1975-09-12 1976-03-31 Nouveaux derives de 5-thiazol methane amine, un procede pour leur preparation, leur application a titre de medicaments Granted FR2372628A2 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FR7609337A FR2372628A2 (fr) 1976-03-31 1976-03-31 Nouveaux derives de 5-thiazol methane amine, un procede pour leur preparation, leur application a titre de medicaments
SE7609666A SE7609666L (sv) 1975-09-12 1976-09-01 Sett att framstella nya 5-aminometyltiazolderivat
US05/721,370 US4108994A (en) 1975-09-12 1976-09-08 5-thiazole-methane-amines, and their use as antilipolytics
AU17630/76A AU499425B2 (en) 1975-09-12 1976-09-10 5-thiazole methane amine derivatives
NL7610062A NL7610062A (nl) 1975-09-12 1976-09-10 Werkwijze voor de bereiding van 5-thiazolyl- methylaminen en zouten daarvan, alsmede een werkwijze voor de bereiding van preparaten die ze bevatten.
CH1157176A CH613958A5 (en) 1975-09-12 1976-09-10 Process for the preparation of new 5-thiazolemethanamine derivatives and of their salts
JP51107981A JPS5236664A (en) 1975-09-12 1976-09-10 Production of novel 55 thiazolemethaneamine derivatives and salts and pharmaceutical composition
CA261,119A CA1082716A (fr) 1975-09-12 1976-09-10 Procede de preparation de nouveaux derives de 5- thiazole methane amine
DK408176A DK408176A (da) 1975-09-12 1976-09-10 Fremgangsmade til fremstilling af 5-thiazolmethanaminderivater eller salte deraf
LU75764A LU75764A1 (fr) 1975-09-12 1976-09-10
ES451466A ES451466A1 (es) 1975-09-12 1976-09-11 Procedimiento para la preparacion de nuevos derivados de 5- tiazol-metanoamina.
DE19762641129 DE2641129A1 (de) 1975-09-12 1976-09-13 Derivate des 5-aminomethylthiazols, ihr herstellungsverfahren und pharmazeutische zusammensetzungen
IE2042/76A IE44294B1 (en) 1975-09-12 1976-09-13 5-thiazole methane amine derivatives and salts thereof, processes for preparing them,and pharmaceuitcal compositions containing them
GB37770/76A GB1526038A (en) 1975-09-12 1976-09-13 5-thiazole methane amine derivatives and salts thereof processes for preparing them and pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7609337A FR2372628A2 (fr) 1976-03-31 1976-03-31 Nouveaux derives de 5-thiazol methane amine, un procede pour leur preparation, leur application a titre de medicaments

Publications (2)

Publication Number Publication Date
FR2372628A2 true FR2372628A2 (fr) 1978-06-30
FR2372628B2 FR2372628B2 (fr) 1979-03-23

Family

ID=9171209

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7609337A Granted FR2372628A2 (fr) 1975-09-12 1976-03-31 Nouveaux derives de 5-thiazol methane amine, un procede pour leur preparation, leur application a titre de medicaments

Country Status (1)

Country Link
FR (1) FR2372628A2 (fr)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Also Published As

Publication number Publication date
FR2372628B2 (fr) 1979-03-23

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