FR2372813A2 - Derives d'isoxazoles, leur procede de preparation et leur application en therapeutique - Google Patents
Derives d'isoxazoles, leur procede de preparation et leur application en therapeutiqueInfo
- Publication number
- FR2372813A2 FR2372813A2 FR7736546A FR7736546A FR2372813A2 FR 2372813 A2 FR2372813 A2 FR 2372813A2 FR 7736546 A FR7736546 A FR 7736546A FR 7736546 A FR7736546 A FR 7736546A FR 2372813 A2 FR2372813 A2 FR 2372813A2
- Authority
- FR
- France
- Prior art keywords
- preparation process
- therapeutic application
- isoxazoles
- derivatives
- isoxazoles derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title abstract 2
- 150000002545 isoxazoles Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- PAYRUJLWNCNPSJ-UHFFFAOYSA-N Aniline Chemical compound NC1=CC=CC=C1 PAYRUJLWNCNPSJ-UHFFFAOYSA-N 0.000 abstract 2
- VQBXUKGMJCPBMF-UHFFFAOYSA-N 5-methyl-1,2-oxazole-4-carboxylic acid Chemical compound CC=1ON=CC=1C(O)=O VQBXUKGMJCPBMF-UHFFFAOYSA-N 0.000 abstract 1
- 229940051881 anilide analgesics and antipyretics Drugs 0.000 abstract 1
- 150000003931 anilides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
L'invention a pour objet des anilides de l'acide-5-méthylisoxazole-4-carboxylique du type décrit au brevet principal, ainsi qu'un procédé sur leur préparation qui consiste à faire réagir une aniline de formule III :
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762655094 DE2655094A1 (de) | 1976-12-04 | 1976-12-04 | Isoxazolderivate, verfahren zu ihrer herstellung und diese enthaltende mittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2372813A2 true FR2372813A2 (fr) | 1978-06-30 |
| FR2372813B2 FR2372813B2 (fr) | 1980-06-20 |
Family
ID=5994722
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7736546A Granted FR2372813A2 (fr) | 1976-12-04 | 1977-12-05 | Derives d'isoxazoles, leur procede de preparation et leur application en therapeutique |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5371069A (fr) |
| AT (1) | AT362788B (fr) |
| BE (1) | BE861502R (fr) |
| CA (1) | CA1094564A (fr) |
| CH (1) | CH614945A5 (fr) |
| DE (1) | DE2655094A1 (fr) |
| DK (1) | DK538577A (fr) |
| ES (1) | ES464553A2 (fr) |
| FR (1) | FR2372813A2 (fr) |
| GB (1) | GB1595467A (fr) |
| IE (1) | IE46102B1 (fr) |
| IT (1) | IT1113801B (fr) |
| LU (1) | LU78626A1 (fr) |
| NL (1) | NL7713148A (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2538806A1 (fr) * | 1982-12-30 | 1984-07-06 | Bago Sa Labor | Composes phenyl-3 methyl isoxazole-5 carboxy-4 anilides substitues, actifs therapeutiquement contre l'inflammation et la douleur |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1980000964A1 (fr) * | 1978-11-03 | 1980-05-15 | American Cyanamid Co | Agents anti-inflammatoires comprenant des 2-carbonyl-3-hydroxy-2-alkenonitriles |
| EP0035285A3 (fr) * | 1979-08-17 | 1981-10-14 | American Cyanamid Company | Phénylester d'acides isoxazole carboxyliques, compositions pharmaceutiques contenant certains de ces esters, et leur procédé de préparation |
| DE3247454A1 (de) * | 1982-12-22 | 1984-06-28 | Laboratorios Bago S.A., Buenos Aires | Substituierte 3-phenyl-5-methyl-isoxazol-4-carboxy-anilide, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US20040110802A1 (en) * | 2002-08-23 | 2004-06-10 | Atli Thorarensen | Antibacterial benzoic acid derivatives |
| WO2026057018A1 (fr) * | 2024-09-12 | 2026-03-19 | Fulcrum Therapeutics, Inc. | Inhibiteurs de nox et leurs méthodes d'utilisation |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2126329A (en) * | 1936-03-20 | 1938-08-09 | Hoffmann La Roche | Amide derivatives of isoxazole carboxylic acids |
| US2288863A (en) * | 1940-02-27 | 1942-07-07 | Hoffmann La Roche | Process for the manufacture of substituted amides of 3,5-dimethylisoxazole-4-carboxylic acid |
-
1976
- 1976-12-04 DE DE19762655094 patent/DE2655094A1/de not_active Withdrawn
-
1977
- 1977-11-15 CH CH1393377A patent/CH614945A5/xx not_active IP Right Cessation
- 1977-11-29 NL NL7713148A patent/NL7713148A/xx not_active Application Discontinuation
- 1977-11-29 ES ES464553A patent/ES464553A2/es not_active Expired
- 1977-12-02 AT AT0866277A patent/AT362788B/de not_active IP Right Cessation
- 1977-12-02 IE IE245177A patent/IE46102B1/en unknown
- 1977-12-02 DK DK538577A patent/DK538577A/da unknown
- 1977-12-02 CA CA292,276A patent/CA1094564A/fr not_active Expired
- 1977-12-02 GB GB5034677A patent/GB1595467A/en not_active Expired
- 1977-12-02 LU LU78626A patent/LU78626A1/xx unknown
- 1977-12-02 IT IT3035177A patent/IT1113801B/it active
- 1977-12-03 JP JP14562177A patent/JPS5371069A/ja active Pending
- 1977-12-05 BE BE183169A patent/BE861502R/fr not_active IP Right Cessation
- 1977-12-05 FR FR7736546A patent/FR2372813A2/fr active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2126329A (en) * | 1936-03-20 | 1938-08-09 | Hoffmann La Roche | Amide derivatives of isoxazole carboxylic acids |
| US2288863A (en) * | 1940-02-27 | 1942-07-07 | Hoffmann La Roche | Process for the manufacture of substituted amides of 3,5-dimethylisoxazole-4-carboxylic acid |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2538806A1 (fr) * | 1982-12-30 | 1984-07-06 | Bago Sa Labor | Composes phenyl-3 methyl isoxazole-5 carboxy-4 anilides substitues, actifs therapeutiquement contre l'inflammation et la douleur |
Also Published As
| Publication number | Publication date |
|---|---|
| CA1094564A (fr) | 1981-01-27 |
| DK538577A (da) | 1978-06-05 |
| ES464553A2 (es) | 1979-08-01 |
| BE861502R (fr) | 1978-06-05 |
| NL7713148A (nl) | 1978-06-06 |
| CH614945A5 (en) | 1979-12-28 |
| ATA866277A (de) | 1980-11-15 |
| AT362788B (de) | 1981-06-10 |
| LU78626A1 (fr) | 1978-07-11 |
| DE2655094A1 (de) | 1978-06-15 |
| FR2372813B2 (fr) | 1980-06-20 |
| IE46102B1 (en) | 1983-02-23 |
| IT1113801B (it) | 1986-01-27 |
| GB1595467A (en) | 1981-08-12 |
| JPS5371069A (en) | 1978-06-24 |
| IE46102L (en) | 1978-06-04 |
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