FR2373545A1 - Procede pour la preparation d'ethers de l'acide clavulanique - Google Patents
Procede pour la preparation d'ethers de l'acide clavulaniqueInfo
- Publication number
- FR2373545A1 FR2373545A1 FR7736817A FR7736817A FR2373545A1 FR 2373545 A1 FR2373545 A1 FR 2373545A1 FR 7736817 A FR7736817 A FR 7736817A FR 7736817 A FR7736817 A FR 7736817A FR 2373545 A1 FR2373545 A1 FR 2373545A1
- Authority
- FR
- France
- Prior art keywords
- compounds
- formula
- clavulanic acid
- ethers
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- HZZVJAQRINQKSD-UHFFFAOYSA-N Clavulanic acid Natural products OC(=O)C1C(=CCO)OC2CC(=O)N21 HZZVJAQRINQKSD-UHFFFAOYSA-N 0.000 title abstract 2
- HZZVJAQRINQKSD-PBFISZAISA-N clavulanic acid Chemical compound OC(=O)[C@H]1C(=C/CO)/O[C@@H]2CC(=O)N21 HZZVJAQRINQKSD-PBFISZAISA-N 0.000 title abstract 2
- 229960003324 clavulanic acid Drugs 0.000 title abstract 2
- 150000002170 ethers Chemical class 0.000 title 1
- 150000001733 carboxylic acid esters Chemical class 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 2
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 150000001734 carboxylic acid salts Chemical class 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 150000002960 penicillins Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical class O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Cette invention concerne la préparation d'éthers de l'acide. Ces composés répondent à la formule :
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB51808/76A GB1589367A (en) | 1976-12-11 | 1976-12-11 | Clavulanic acid ethers |
| GB1111677 | 1977-03-16 | ||
| GB3875377 | 1977-09-16 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2373545A1 true FR2373545A1 (fr) | 1978-07-07 |
| FR2373545B1 FR2373545B1 (fr) | 1982-04-16 |
Family
ID=27256638
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7736817A Granted FR2373545A1 (fr) | 1976-12-11 | 1977-12-07 | Procede pour la preparation d'ethers de l'acide clavulanique |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5377090A (fr) |
| AR (1) | AR216117A1 (fr) |
| AT (1) | AT356269B (fr) |
| CA (1) | CA1097653A (fr) |
| CH (1) | CH636880A5 (fr) |
| DE (1) | DE2754763A1 (fr) |
| ES (1) | ES464941A1 (fr) |
| FR (1) | FR2373545A1 (fr) |
| GR (1) | GR64001B (fr) |
| IE (1) | IE46436B1 (fr) |
| IL (1) | IL53465A (fr) |
| MX (1) | MX4846E (fr) |
| NL (1) | NL7713644A (fr) |
| NZ (1) | NZ185849A (fr) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0002370B1 (fr) * | 1977-12-02 | 1983-05-11 | Beecham Group Plc | Procédé pour la préparation de derivés ether de l'acide clavulanique |
| DE3062347D1 (en) * | 1979-08-11 | 1983-04-21 | Beecham Group Plc | Process for the preparation of derivatives of clavulanic acid |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2335222A1 (fr) * | 1975-12-17 | 1977-07-15 | Glaxo Lab Ltd | Derives etherifies de l'acide clavulanique, leur preparation et compositions therapeutiques en contenant |
-
1977
- 1977-11-25 IL IL53465A patent/IL53465A/xx unknown
- 1977-12-05 NZ NZ185849A patent/NZ185849A/xx unknown
- 1977-12-07 FR FR7736817A patent/FR2373545A1/fr active Granted
- 1977-12-08 DE DE19772754763 patent/DE2754763A1/de not_active Withdrawn
- 1977-12-09 MX MX776680U patent/MX4846E/es unknown
- 1977-12-09 CA CA292,807A patent/CA1097653A/fr not_active Expired
- 1977-12-09 AR AR270306A patent/AR216117A1/es active
- 1977-12-09 NL NL7713644A patent/NL7713644A/xx not_active Application Discontinuation
- 1977-12-09 ES ES464941A patent/ES464941A1/es not_active Expired
- 1977-12-09 JP JP14865677A patent/JPS5377090A/ja active Pending
- 1977-12-09 IE IE2501/77A patent/IE46436B1/en unknown
- 1977-12-09 AT AT881677A patent/AT356269B/de not_active IP Right Cessation
- 1977-12-09 GR GR54946A patent/GR64001B/el unknown
- 1977-12-12 CH CH1523577A patent/CH636880A5/de not_active IP Right Cessation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2335222A1 (fr) * | 1975-12-17 | 1977-07-15 | Glaxo Lab Ltd | Derives etherifies de l'acide clavulanique, leur preparation et compositions therapeutiques en contenant |
Non-Patent Citations (1)
| Title |
|---|
| NV134A/74 * |
Also Published As
| Publication number | Publication date |
|---|---|
| MX4846E (es) | 1982-10-28 |
| NZ185849A (en) | 1980-11-28 |
| GR64001B (en) | 1980-01-18 |
| NL7713644A (nl) | 1978-06-13 |
| ATA881677A (de) | 1979-09-15 |
| IE772501L (en) | 1978-06-11 |
| IE46436B1 (en) | 1983-06-15 |
| IL53465A (en) | 1980-11-30 |
| AR216117A1 (es) | 1979-11-30 |
| FR2373545B1 (fr) | 1982-04-16 |
| ES464941A1 (es) | 1979-12-16 |
| DE2754763A1 (de) | 1978-06-15 |
| AT356269B (de) | 1980-04-25 |
| CA1097653A (fr) | 1981-03-17 |
| JPS5377090A (en) | 1978-07-08 |
| CH636880A5 (en) | 1983-06-30 |
| IL53465A0 (en) | 1978-01-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |