FR2390964A1 - Associations medicamenteuses comprenant de la prostacycline ou de la dihydroprostacycline - Google Patents

Associations medicamenteuses comprenant de la prostacycline ou de la dihydroprostacycline

Info

Publication number
FR2390964A1
FR2390964A1 FR7814729A FR7814729A FR2390964A1 FR 2390964 A1 FR2390964 A1 FR 2390964A1 FR 7814729 A FR7814729 A FR 7814729A FR 7814729 A FR7814729 A FR 7814729A FR 2390964 A1 FR2390964 A1 FR 2390964A1
Authority
FR
France
Prior art keywords
blood
pharmaceutical composition
dihydroprostacycline
prostacycline
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7814729A
Other languages
English (en)
Other versions
FR2390964B1 (fr
Inventor
Pedro Cuatrecasas
Salvador Moncada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of FR2390964A1 publication Critical patent/FR2390964A1/fr
Application granted granted Critical
Publication of FR2390964B1 publication Critical patent/FR2390964B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne de nouvelles associations médicamenteuses. Elles comprennent de la prostacycline ou de la dihydroprostacycline ou un de leurs sels convenant en pharmacie, avec un inhibiteur de phosphodiestérase, et elles peuvent être mises sous forme de médicaments divers avec des véhicules pharmaceutiques. Elles peuvent être utilisées notamment pour prévenir l'agrégation des plaquettes sanguines, par exemple dans le traitement de thromboses, de lésions gastriques et de plaies, dans la circulation sanguine extracorporelle et dans les procédés de séparation des constituants du sang.
FR7814729A 1977-05-20 1978-05-18 Associations medicamenteuses comprenant de la prostacycline ou de la dihydroprostacycline Granted FR2390964A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79900777A 1977-05-20 1977-05-20
GB3526177 1977-08-23

Publications (2)

Publication Number Publication Date
FR2390964A1 true FR2390964A1 (fr) 1978-12-15
FR2390964B1 FR2390964B1 (fr) 1980-07-11

Family

ID=26262642

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7814729A Granted FR2390964A1 (fr) 1977-05-20 1978-05-18 Associations medicamenteuses comprenant de la prostacycline ou de la dihydroprostacycline

Country Status (8)

Country Link
JP (1) JPS542335A (fr)
CH (1) CH643458A5 (fr)
DE (1) DE2821737A1 (fr)
FR (1) FR2390964A1 (fr)
HU (1) HU180548B (fr)
IT (1) IT1105506B (fr)
NL (1) NL7805402A (fr)
SE (1) SE443716B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0005768A1 (fr) * 1978-05-17 1979-12-12 The Wellcome Foundation Limited Formulations pharmaceutiques contenant des composés de prostaglandine et méthode pour leur fabrication

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3526362A1 (de) * 1985-07-19 1987-01-22 Schering Ag Prostacycline, ihre analoga oder prostaglandine und thromboxanantagonisten zur behandlung von thrombotischen und thromboembolischen krankheitsbildern
ES2045124T3 (es) * 1987-07-14 1994-01-16 Sankyo Co Un proceso para la preparacion de una composicion antitrombotica.

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2235678A1 (en) * 1973-07-02 1975-01-31 Merck & Co Inc Topical antipsoriasis agents - contg. prostaglandin E1 or E2

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2235678A1 (en) * 1973-07-02 1975-01-31 Merck & Co Inc Topical antipsoriasis agents - contg. prostaglandin E1 or E2

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0005768A1 (fr) * 1978-05-17 1979-12-12 The Wellcome Foundation Limited Formulations pharmaceutiques contenant des composés de prostaglandine et méthode pour leur fabrication
FR2425856A1 (fr) * 1978-05-17 1979-12-14 Wellcome Found Medicament a base de prostaglandines

Also Published As

Publication number Publication date
IT1105506B (it) 1985-11-04
DE2821737C2 (fr) 1988-05-19
CH643458A5 (en) 1984-06-15
SE443716B (sv) 1986-03-10
JPS542335A (en) 1979-01-09
IT7849485A0 (it) 1978-05-22
DE2821737A1 (de) 1978-11-30
FR2390964B1 (fr) 1980-07-11
SE7805707L (sv) 1978-11-21
NL7805402A (nl) 1978-11-22
HU180548B (en) 1983-03-28

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