FR2391191A1 - Nouveaux composes polypeptidiques, lyeptidiques, leur preparation et leur application comme medicaments - Google Patents

Nouveaux composes polypeptidiques, lyeptidiques, leur preparation et leur application comme medicaments

Info

Publication number
FR2391191A1
FR2391191A1 FR7814372A FR7814372A FR2391191A1 FR 2391191 A1 FR2391191 A1 FR 2391191A1 FR 7814372 A FR7814372 A FR 7814372A FR 7814372 A FR7814372 A FR 7814372A FR 2391191 A1 FR2391191 A1 FR 2391191A1
Authority
FR
France
Prior art keywords
preparation
lyeptidic
new
application
medicinal products
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7814372A
Other languages
English (en)
Inventor
Francois Cardinaux
Janos Pless
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2391191A1 publication Critical patent/FR2391191A1/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • C07K14/70—Enkephalins
    • C07K14/702—Enkephalins with at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

L'invention concerne de nouveaux polypeptides et leur préparation. Les composés de l'invention répondent à la formule : A - B- Gly - D - E dans laquelle A représente un reste alpha -amino-phénéthylcarbonyle substitué; B désigne un groupe -D-Ala-,-D-Ser-, -D-Thr-, -Aib- ou -D-Met ou un reste du D-méthionine-sulfoxyde ou de la D-méthionine-sulfone; D représente un groupe alpha -amino-phénéthylcarbonyle éventuellement substitué et E signifie un reste aminé. Ces polypeptides peuvent être utilisés en thérapeutique comme substances actives de médicaments.
FR7814372A 1977-05-16 1978-05-16 Nouveaux composes polypeptidiques, lyeptidiques, leur preparation et leur application comme medicaments Withdrawn FR2391191A1 (fr)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
CH606177 1977-05-16
CH740277 1977-06-16
CH751877 1977-06-20
CH757677 1977-06-21
CH757777 1977-06-21
CH771377 1977-06-23
CH1386277 1977-11-14

Publications (1)

Publication Number Publication Date
FR2391191A1 true FR2391191A1 (fr) 1978-12-15

Family

ID=27561110

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7814372A Withdrawn FR2391191A1 (fr) 1977-05-16 1978-05-16 Nouveaux composes polypeptidiques, lyeptidiques, leur preparation et leur application comme medicaments

Country Status (12)

Country Link
JP (1) JPS53141236A (fr)
AU (1) AU3611378A (fr)
BE (1) BE867121A (fr)
DE (1) DE2819277A1 (fr)
DK (1) DK199578A (fr)
FR (1) FR2391191A1 (fr)
GB (1) GB1601754A (fr)
IL (1) IL54714A0 (fr)
IT (1) IT7849374A0 (fr)
NL (1) NL7805165A (fr)
NZ (1) NZ187280A (fr)
PT (1) PT68036B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044451A1 (fr) * 1980-07-17 1982-01-27 Sandoz Ag Pentapeptides, leurs procédés de préparation, compositions pharmaceutiques les contenant et leur emploi
EP0077122A3 (en) * 1981-09-15 1984-06-27 Imperial Chemical Industries Plc Amino-substituted tetralins and related homocyclic compounds
EP0649443A4 (fr) * 1992-06-30 1995-11-08 Legomer Partners Lp Matieres derivees d'oxazolone.
EP2419117A4 (fr) * 2009-04-13 2014-10-22 Elc Man Llc Peptide de méthionine sulfoxyde, compositions et procédés d'utilisation

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1604850A (en) * 1977-11-24 1981-12-16 Wellcome Found Biologically active peptides
JPS55118444A (en) * 1979-03-07 1980-09-11 Takeda Chem Ind Ltd Tetrapeptide derivative
IL63205A0 (en) * 1980-07-02 1981-09-13 Merrell Dow Pharma Antiviral 1-aryl-5amino-penten-3-ones
JPS5756447A (en) * 1980-07-17 1982-04-05 Sandoz Ag Novel pentapeptides
EP0076557B1 (fr) * 1981-06-22 1985-11-13 Imperial Chemical Industries Plc Peptides et pseudopeptides ayant au N-terminus deux substituants
CN115143181B (zh) * 2021-03-31 2024-07-30 日本电产株式会社 中空轴及中空轴的制造方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2338925A1 (fr) * 1976-01-26 1977-08-19 Wellcome Found Nouveaux peptides et medicament contenant ces substances
FR2339590A1 (fr) * 1976-02-02 1977-08-26 Sandoz Sa Nouveaux composes polypeptidiques, leur preparation et leur application comme medicaments
FR2359120A1 (fr) * 1976-07-19 1978-02-17 Sandoz Sa Nouveaux composes polypeptidiques, leur preparation et leur application comme medicaments

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2338925A1 (fr) * 1976-01-26 1977-08-19 Wellcome Found Nouveaux peptides et medicament contenant ces substances
FR2339590A1 (fr) * 1976-02-02 1977-08-26 Sandoz Sa Nouveaux composes polypeptidiques, leur preparation et leur application comme medicaments
FR2359120A1 (fr) * 1976-07-19 1978-02-17 Sandoz Sa Nouveaux composes polypeptidiques, leur preparation et leur application comme medicaments

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EXBK/77 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0044451A1 (fr) * 1980-07-17 1982-01-27 Sandoz Ag Pentapeptides, leurs procédés de préparation, compositions pharmaceutiques les contenant et leur emploi
EP0077122A3 (en) * 1981-09-15 1984-06-27 Imperial Chemical Industries Plc Amino-substituted tetralins and related homocyclic compounds
EP0649443A4 (fr) * 1992-06-30 1995-11-08 Legomer Partners Lp Matieres derivees d'oxazolone.
EP2419117A4 (fr) * 2009-04-13 2014-10-22 Elc Man Llc Peptide de méthionine sulfoxyde, compositions et procédés d'utilisation

Also Published As

Publication number Publication date
AU3611378A (en) 1979-11-22
BE867121A (fr) 1978-11-16
NL7805165A (nl) 1978-11-20
NZ187280A (en) 1981-05-15
DK199578A (da) 1978-11-17
DE2819277A1 (de) 1978-11-23
JPS53141236A (en) 1978-12-08
IL54714A0 (en) 1978-07-31
IT7849374A0 (it) 1978-05-16
GB1601754A (en) 1981-11-04
PT68036A (en) 1978-06-01
PT68036B (en) 1980-03-05

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ST Notification of lapse