FR2400518A1 - Benzo(b)thieno(3,2-c) et (2,3-c)pyridines, leur procede de preparation et leur application en therapeutique - Google Patents
Benzo(b)thieno(3,2-c) et (2,3-c)pyridines, leur procede de preparation et leur application en therapeutiqueInfo
- Publication number
- FR2400518A1 FR2400518A1 FR7725238A FR7725238A FR2400518A1 FR 2400518 A1 FR2400518 A1 FR 2400518A1 FR 7725238 A FR7725238 A FR 7725238A FR 7725238 A FR7725238 A FR 7725238A FR 2400518 A1 FR2400518 A1 FR 2400518A1
- Authority
- FR
- France
- Prior art keywords
- platelet aggregation
- blood platelet
- antiinflammatory agents
- benzothieno
- useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229940121363 anti-inflammatory agent Drugs 0.000 title abstract 2
- 239000002260 anti-inflammatory agent Substances 0.000 title abstract 2
- WIUZHVZUGQDRHZ-UHFFFAOYSA-N [1]benzothiolo[3,2-b]pyridine Chemical compound C1=CN=C2C3=CC=CC=C3SC2=C1 WIUZHVZUGQDRHZ-UHFFFAOYSA-N 0.000 title 1
- 239000000106 platelet aggregation inhibitor Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- DHKHKXVYLBGOIT-UHFFFAOYSA-N 1,1-Diethoxyethane Chemical compound CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000005605 benzo group Chemical group 0.000 abstract 2
- 125000001475 halogen functional group Chemical group 0.000 abstract 2
- -1 -CONH2 Chemical group 0.000 abstract 1
- SPEUIVXLLWOEMJ-UHFFFAOYSA-N acetaldehyde dimethyl acetal Natural products COC(C)OC SPEUIVXLLWOEMJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
- DBDCNCCRPKTRSD-UHFFFAOYSA-N thieno[3,2-b]pyridine Chemical compound C1=CC=C2SC=CC2=N1 DBDCNCCRPKTRSD-UHFFFAOYSA-N 0.000 abstract 1
- 229940125670 thienopyridine Drugs 0.000 abstract 1
- 239000002175 thienopyridine Substances 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/58—Radicals substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
L'invention a pour objet des dérivés de benzoØbõ thiéno pyridine répondant à l'une ou l'autre des formules :
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7725238A FR2400518A1 (fr) | 1977-08-18 | 1977-08-18 | Benzo(b)thieno(3,2-c) et (2,3-c)pyridines, leur procede de preparation et leur application en therapeutique |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7725238A FR2400518A1 (fr) | 1977-08-18 | 1977-08-18 | Benzo(b)thieno(3,2-c) et (2,3-c)pyridines, leur procede de preparation et leur application en therapeutique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2400518A1 true FR2400518A1 (fr) | 1979-03-16 |
| FR2400518B1 FR2400518B1 (fr) | 1980-02-01 |
Family
ID=9194594
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7725238A Granted FR2400518A1 (fr) | 1977-08-18 | 1977-08-18 | Benzo(b)thieno(3,2-c) et (2,3-c)pyridines, leur procede de preparation et leur application en therapeutique |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2400518A1 (fr) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0206225A3 (fr) * | 1985-06-27 | 1987-09-23 | MERCK PATENT GmbH | Dérivés de l'indole |
| US4985422A (en) * | 1988-04-27 | 1991-01-15 | Glaxo Group Limited | Lactam derivatives |
| US6541505B1 (en) | 1998-12-24 | 2003-04-01 | Aventis Pharmaceuticals Inc. | Substituted (aminoiminomethyl or aminomethyl) benzoheteroaryl compounds |
-
1977
- 1977-08-18 FR FR7725238A patent/FR2400518A1/fr active Granted
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0206225A3 (fr) * | 1985-06-27 | 1987-09-23 | MERCK PATENT GmbH | Dérivés de l'indole |
| US4740602A (en) * | 1985-06-27 | 1988-04-26 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Indole derivatives |
| US4985422A (en) * | 1988-04-27 | 1991-01-15 | Glaxo Group Limited | Lactam derivatives |
| US6541505B1 (en) | 1998-12-24 | 2003-04-01 | Aventis Pharmaceuticals Inc. | Substituted (aminoiminomethyl or aminomethyl) benzoheteroaryl compounds |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2400518B1 (fr) | 1980-02-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |