FR2401933A1 - Nouveau complexe de coordination du platine et medicament le contenant - Google Patents

Nouveau complexe de coordination du platine et medicament le contenant

Info

Publication number
FR2401933A1
FR2401933A1 FR7824771A FR7824771A FR2401933A1 FR 2401933 A1 FR2401933 A1 FR 2401933A1 FR 7824771 A FR7824771 A FR 7824771A FR 7824771 A FR7824771 A FR 7824771A FR 2401933 A1 FR2401933 A1 FR 2401933A1
Authority
FR
France
Prior art keywords
coordination complex
drug container
new platinum
platinum
container coordination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7824771A
Other languages
English (en)
Other versions
FR2401933B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Government of the United States of America
Original Assignee
Government of the United States of America
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/828,926 external-priority patent/US4137248A/en
Application filed by Government of the United States of America filed Critical Government of the United States of America
Publication of FR2401933A1 publication Critical patent/FR2401933A1/fr
Application granted granted Critical
Publication of FR2401933B1 publication Critical patent/FR2401933B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention a trait au domaine de la chimie médicale. Elle concerne un complexe de coordination du platine, à savoir le 4-carboxyphtalato-(1,2-diaminocyclohexane)-platine II ou ses sels de métaux alcalins. Ce composé peut être utilisé en association avec le cyclophosphamide, le 5-fluoracile et/ou l'hydroxyurée. Application à l'atténuation de la leucémie de la souris.
FR7824771A 1977-08-29 1978-08-28 Nouveau complexe de coordination du platine et medicament le contenant Granted FR2401933A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/828,926 US4137248A (en) 1977-08-29 1977-08-29 Compound, 4-carboxyphthalato(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof
US05/926,035 US4206226A (en) 1977-08-29 1978-07-19 Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia

Publications (2)

Publication Number Publication Date
FR2401933A1 true FR2401933A1 (fr) 1979-03-30
FR2401933B1 FR2401933B1 (fr) 1980-06-20

Family

ID=27125226

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7824771A Granted FR2401933A1 (fr) 1977-08-29 1978-08-28 Nouveau complexe de coordination du platine et medicament le contenant

Country Status (8)

Country Link
US (1) US4206226A (fr)
JP (1) JPS5446752A (fr)
AU (1) AU517578B2 (fr)
BE (1) BE870000A (fr)
CA (1) CA1104578A (fr)
DE (1) DE2837237A1 (fr)
FR (1) FR2401933A1 (fr)
GB (1) GB2003468B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2481289A1 (fr) * 1980-04-29 1981-10-30 Sanofi Sa Compose complexe isocitrate du platine, son procede de preparation et son application therapeutique
EP0137900A1 (fr) * 1983-05-10 1985-04-24 Andrulis Research Corporation Complexes bis-platiniques comme agents antitumoraux
EP0169645A1 (fr) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Composés de coordination du platine

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8204067A (nl) * 1982-10-21 1984-05-16 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiaminecomplex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.
US4581224A (en) * 1980-08-08 1986-04-08 Regents Of The University Of Minnesota Inhibition of undesired effect of platinum compounds
US4594238A (en) * 1980-08-08 1986-06-10 Regents Of University Of Minnesota Inhibition of undesired effect of platinum compounds
US4562275A (en) * 1984-03-23 1985-12-31 Bristol-Myers Co. Antitumor platinum complexes
US4739087A (en) * 1985-01-10 1988-04-19 Bristol-Myers Company Antineoplastic platinum complexes
JPS6296A (ja) * 1985-03-06 1987-01-06 Sumitomo Pharmaceut Co Ltd 脂溶性白金（２）錯体
US4898852A (en) * 1987-06-02 1990-02-06 Walsh William E Cyclopolgalcturonic acid composition and treatment
DK0457921T3 (da) * 1989-12-12 1996-11-18 Toray Industries Hidtil ukendt platin(II)kompleks og middel til behandling af en malign tumor
JPH0776230B2 (ja) * 1992-01-13 1995-08-16 田中貴金属工業株式会社 白金化合物の製造方法
US20050089958A1 (en) * 1996-01-09 2005-04-28 Genentech, Inc. Apo-2 ligand
US6030945A (en) * 1996-01-09 2000-02-29 Genentech, Inc. Apo-2 ligand
US6998116B1 (en) 1996-01-09 2006-02-14 Genentech, Inc. Apo-2 ligand
DE102004005906B3 (de) 2004-02-05 2005-09-29 W.C. Heraeus Gmbh Verfahren zur Herstellung von 1,2-Diaminocylohexan-Platin(II)-Komplexen

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2481289A1 (fr) * 1980-04-29 1981-10-30 Sanofi Sa Compose complexe isocitrate du platine, son procede de preparation et son application therapeutique
EP0039272A3 (en) * 1980-04-29 1982-05-05 Sanofi, Societe Dite: Platinum-isocitrate complex, process for its preparation and its therapeutical application
EP0137900A1 (fr) * 1983-05-10 1985-04-24 Andrulis Research Corporation Complexes bis-platiniques comme agents antitumoraux
EP0169645A1 (fr) * 1984-06-27 1986-01-29 Johnson Matthey Public Limited Company Composés de coordination du platine

Also Published As

Publication number Publication date
AU517578B2 (en) 1981-08-13
US4206226A (en) 1980-06-03
GB2003468B (en) 1982-01-06
GB2003468A (en) 1979-03-14
DE2837237A1 (de) 1979-03-15
BE870000A (fr) 1978-12-18
JPS5446752A (en) 1979-04-12
AU3915178A (en) 1980-02-28
FR2401933B1 (fr) 1980-06-20
CA1104578A (fr) 1981-07-07

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