FR2404625A1 - Nouveaux 4-aminocyclohexanols et composition pharmaceutique les contenant - Google Patents

Nouveaux 4-aminocyclohexanols et composition pharmaceutique les contenant

Info

Publication number
FR2404625A1
FR2404625A1 FR7827780A FR7827780A FR2404625A1 FR 2404625 A1 FR2404625 A1 FR 2404625A1 FR 7827780 A FR7827780 A FR 7827780A FR 7827780 A FR7827780 A FR 7827780A FR 2404625 A1 FR2404625 A1 FR 2404625A1
Authority
FR
France
Prior art keywords
aminocyclohexanols
new
pharmaceutical composition
composition containing
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7827780A
Other languages
English (en)
Other versions
FR2404625B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FR2404625A1 publication Critical patent/FR2404625A1/fr
Application granted granted Critical
Publication of FR2404625B1 publication Critical patent/FR2404625B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention a trait au domaine de la chimie médicale. Elle concerne de nouveaux 4-aminocyclohexanols et leurs sels d'addition d'acides acceptables du point de vue physiolo gique. Les composés de l'invention sont doués de propriétés analgésiques. On les incorpore à des compositions pharmaceutiques que l'on administre à des mammifères, y compris des êtres humains, dont l'état nécessite un traitement analgésique.
FR7827780A 1977-09-29 1978-09-28 Nouveaux 4-aminocyclohexanols et composition pharmaceutique les contenant Granted FR2404625A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/837,510 US4366172A (en) 1977-09-29 1977-09-29 4-Amino-cyclohexanols, their pharmaceutical compositions and methods of use

Publications (2)

Publication Number Publication Date
FR2404625A1 true FR2404625A1 (fr) 1979-04-27
FR2404625B1 FR2404625B1 (fr) 1981-12-24

Family

ID=25274659

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7827780A Granted FR2404625A1 (fr) 1977-09-29 1978-09-28 Nouveaux 4-aminocyclohexanols et composition pharmaceutique les contenant

Country Status (6)

Country Link
US (1) US4366172A (fr)
JP (1) JPS5459263A (fr)
CH (1) CH635818A5 (fr)
DE (1) DE2839891A1 (fr)
FR (1) FR2404625A1 (fr)
GB (1) GB2005266B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4294761A (en) 1980-02-14 1981-10-13 Eastman Kodak Company Preparation of 7,12-dioxaspiro[5,6]dodecane-3-one
NZ260408A (en) * 1993-05-10 1996-05-28 Euro Celtique Sa Controlled release preparation comprising tramadol
US5891471A (en) * 1993-11-23 1999-04-06 Euro-Celtique, S.A. Pharmaceutical multiparticulates
KR100354702B1 (ko) * 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) * 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE19857475A1 (de) * 1998-12-14 2000-06-15 Gruenenthal Gmbh Substituierte Cycloheptene, deren Herstellung und Verwendung
DE19915601A1 (de) * 1999-04-07 2000-10-19 Gruenenthal Gmbh 3-Amino-3-arylpropan-1-ol-Derivate, deren Herstellung und Verwendung
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
DE10025238A1 (de) * 2000-05-22 2001-11-29 Gruenenthal Gmbh Verwendung substituierter 1-Amino-5-phenylpentan-3-ol- und/oder 1-Amino-6-phenylhexan-3-ol- Verbindungen als Arzneimittel
DE10135637A1 (de) * 2001-07-17 2003-02-06 Gruenenthal Gmbh Substituierte 4-Aminocyclohexanolderivate
PE20030320A1 (es) * 2001-07-17 2003-04-03 Gruenenthal Chemie Derivados sustituidos de 4-aminociclohexanol
DE10135635A1 (de) * 2001-07-17 2003-02-06 Gruenenthal Gmbh Analgetische substituierte 4-Aminocyclohexanolderivate
DE10135636A1 (de) * 2001-07-17 2003-02-06 Gruenenthal Gmbh Substituierte 4-Aminocyclohexanole
DE10161818A1 (de) * 2001-12-14 2003-06-26 Gruenenthal Gmbh Substituierte 1,5-Diaminopentan-3-ol-Verbindungen
DE10213051B4 (de) * 2002-03-23 2013-03-07 Grünenthal GmbH Substituierte 4-Aminocyclohexanole
DE102004023507A1 (de) * 2004-05-10 2005-12-01 Grünenthal GmbH Substituierte Cyclohexylessigsäure-Derivate
CA2682494C (fr) 2007-04-04 2011-10-11 Merck & Co., Inc. Hexahydro-1h-4,7-methanoisoindole-1,3-diones pour le traitement de maladies psychiatriques
ATE537143T1 (de) * 2008-03-27 2011-12-15 Gruenenthal Gmbh Spiro(5.5)undecan derivate
CA2719735A1 (fr) * 2008-03-27 2009-10-01 Gruenenthal Gmbh Derives substitues du 4-aminocyclohexane
JP5599774B2 (ja) * 2008-03-27 2014-10-01 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング ヒドロキシメチルシクロヘキシルアミン類
AU2009228637B2 (en) 2008-03-27 2013-12-19 Grunenthal Gmbh (Hetero-)aryl cyclohexane derivatives
PT2260042E (pt) * 2008-03-27 2011-12-06 Gruenenthal Gmbh Derivados de ciclo-hexano espirocíclicos substituídos
WO2009118174A1 (fr) * 2008-03-27 2009-10-01 Grünenthal GmbH Cyclohexyldiamines substituées
US8389443B2 (en) * 2008-12-02 2013-03-05 Bayer Cropscience Ag Geminal alkoxy/alkylspirocyclic substituted tetramate derivatives

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1295311A (fr) * 1958-02-28 1962-06-08 Parke Davis & Co Procédés pour la fabrication de composés 1-phénylcyclohexane contenant un groupeamino dialiphatiquement substitué
US4113866A (en) * 1977-04-01 1978-09-12 The Upjohn Company Analgetic compounds, compositions and process of treatment

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2520516A (en) * 1945-01-19 1950-08-29 Wm S Merrell Co Cyclic amines and method of making them
US3652589A (en) * 1967-07-27 1972-03-28 Gruenenthal Chemie 1-(m-substituted phenyl)-2-aminomethyl cyclohexanols
US3974157A (en) * 1974-03-04 1976-08-10 Pennwalt Corporation 1-(Amino-alkyl)-2-aryl-cyclohexane alcohols and esters

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1295311A (fr) * 1958-02-28 1962-06-08 Parke Davis & Co Procédés pour la fabrication de composés 1-phénylcyclohexane contenant un groupeamino dialiphatiquement substitué
US4113866A (en) * 1977-04-01 1978-09-12 The Upjohn Company Analgetic compounds, compositions and process of treatment

Also Published As

Publication number Publication date
DE2839891A1 (de) 1979-04-12
FR2404625B1 (fr) 1981-12-24
CH635818A5 (de) 1983-04-29
GB2005266A (en) 1979-04-19
GB2005266B (en) 1982-02-03
US4366172A (en) 1982-12-28
JPS5459263A (en) 1979-05-12

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Legal Events

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