FR2407941A1 - Nouveaux derives de cholesterol - Google Patents

Nouveaux derives de cholesterol

Info

Publication number
FR2407941A1
FR2407941A1 FR7630450A FR7630450A FR2407941A1 FR 2407941 A1 FR2407941 A1 FR 2407941A1 FR 7630450 A FR7630450 A FR 7630450A FR 7630450 A FR7630450 A FR 7630450A FR 2407941 A1 FR2407941 A1 FR 2407941A1
Authority
FR
France
Prior art keywords
cholesterol derivatives
new cholesterol
alcoxy
compounds
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7630450A
Other languages
English (en)
French (fr)
Other versions
FR2407941B1 (2
Inventor
John Joseph Partridge Jr
Milan Radoje Uskokovic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/621,319 external-priority patent/US3994878A/en
Priority claimed from US05/623,859 external-priority patent/US4038272A/en
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2407941A1 publication Critical patent/FR2407941A1/fr
Application granted granted Critical
Publication of FR2407941B1 publication Critical patent/FR2407941B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR7630450A 1975-10-10 1976-10-11 Nouveaux derives de cholesterol Granted FR2407941A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/621,319 US3994878A (en) 1975-10-10 1975-10-10 Syntheses of 24R,25- and 24S,25-dihydroxycholesterol and alkanoyl derivatives thereof
US05/623,859 US4038272A (en) 1975-10-20 1975-10-20 Stereospecific syntheses of 24r,25- and 24s,25-dihydroxycholesterol and alkanoyl derivatives thereof

Publications (2)

Publication Number Publication Date
FR2407941A1 true FR2407941A1 (fr) 1979-06-01
FR2407941B1 FR2407941B1 (2) 1980-05-16

Family

ID=27088923

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7630450A Granted FR2407941A1 (fr) 1975-10-10 1976-10-11 Nouveaux derives de cholesterol
FR7712223A Granted FR2351998A1 (fr) 1975-10-10 1977-04-22 Nouveaux derives de cholesterol et procede pour leur preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7712223A Granted FR2351998A1 (fr) 1975-10-10 1977-04-22 Nouveaux derives de cholesterol et procede pour leur preparation

Country Status (8)

Country Link
JP (1) JPS5246061A (2)
AT (1) AT355236B (2)
CH (1) CH628907A5 (2)
DE (1) DE2645527A1 (2)
FR (2) FR2407941A1 (2)
GB (5) GB1564807A (2)
IT (1) IT1068692B (2)
NL (1) NL7611155A (2)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH644873A5 (de) * 1980-02-12 1984-08-31 Hoffmann La Roche Verfahren zur herstellung von cholesterinderivaten.
CA2848212C (en) 2011-09-08 2022-03-29 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
PT2968369T (pt) 2013-03-13 2018-12-05 Sage Therapeutics Inc Esteroides neuroativos e métodos para o seu uso
HUE071964T2 (hu) 2015-07-06 2025-10-28 Sage Therapeutics Inc Oxiszterolok és alkalmazási eljárásaik
CA2991311C (en) * 2015-07-06 2025-05-06 Sage Therapeutics, Inc. OXYSTEROLS AND THEIR METHODS OF USE
EP3828194B1 (en) 2015-07-06 2025-04-16 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
SMT202200300T1 (it) 2016-04-01 2022-09-14 Sage Therapeutics Inc Ossisteroli e relativi metodi d'uso
WO2017193046A1 (en) 2016-05-06 2017-11-09 Sage Therapeutics, Inc. Oxysterols and methods of use thereof
ES2884071T3 (es) 2016-07-07 2021-12-10 Sage Therapeutics Inc 24-hidroxiesteroles sustituidos en 11 para el tratamiento de afecciones relacionadas con NMDA
ES2935057T3 (es) 2016-09-30 2023-03-01 Sage Therapeutics Inc C7 oxisteroles sustituidos y estos compuestos para su uso como moduladores de la NMDA
RU2019115113A (ru) 2016-10-18 2020-11-24 Сейдж Терапьютикс, Инк. Оксистеролы и способы их применения

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7402846A (2) * 1973-03-02 1974-09-04
US3822254A (en) * 1973-05-21 1974-07-02 Hoffmann La Roche Synthesis of 25-hydroxycholesterol

Also Published As

Publication number Publication date
DE2645527A1 (de) 1977-04-21
FR2351998B1 (2) 1980-04-25
FR2351998A1 (fr) 1977-12-16
CH628907A5 (en) 1982-03-31
GB1564810A (en) 1980-04-16
NL7611155A (nl) 1977-04-13
GB1564809A (en) 1980-04-16
GB1564808A (en) 1980-04-16
FR2407941B1 (2) 1980-05-16
JPS5246061A (en) 1977-04-12
GB1564806A (en) 1980-04-16
GB1564807A (en) 1980-04-16
IT1068692B (it) 1985-03-21
AT355236B (de) 1980-02-25
ATA751376A (de) 1979-07-15

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Legal Events

Date Code Title Description
ST Notification of lapse