FR2414918A1 - Procede de preparation in vitro d'un agent immunotherapeutique pour le traitement du cancer - Google Patents
Procede de preparation in vitro d'un agent immunotherapeutique pour le traitement du cancerInfo
- Publication number
- FR2414918A1 FR2414918A1 FR7835235A FR7835235A FR2414918A1 FR 2414918 A1 FR2414918 A1 FR 2414918A1 FR 7835235 A FR7835235 A FR 7835235A FR 7835235 A FR7835235 A FR 7835235A FR 2414918 A1 FR2414918 A1 FR 2414918A1
- Authority
- FR
- France
- Prior art keywords
- cancer
- treatment
- medium
- extracted
- immunotherapeutic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 201000011510 cancer Diseases 0.000 title abstract 4
- 239000002955 immunomodulating agent Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 238000000338 in vitro Methods 0.000 title 1
- 210000004698 lymphocyte Anatomy 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 2
- 102000036639 antigens Human genes 0.000 abstract 2
- 108091007433 antigens Proteins 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 230000002238 attenuated effect Effects 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 210000002540 macrophage Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Procédé de préparation d'un agent immunothérapeutique pour le traitement du cancer, dans lequel : 1. on extrait dans un milieu liquide des antigènes à partir de cellules cancéreuses vivantes à activité atténuée par des rayons; 2. on met en contact le milieu contenant les antigènes avec des cellules macrophages et on extrait le milieu liquide résultant; 3. on sensibilise des lymphocytes normaux provenant du sang d'un donneur en bonne santé en mettant en contact ces lymphocytes avec le milieu obtenu à l'étape précédente dans des conditions de culture; 4. on extrait des lymphocytes sensibilisés du milieu résultant et on les met en suspension dans une solution support pour administration à un patient atteint d'un cancer.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP15148677A JPS5484017A (en) | 1977-12-16 | 1977-12-16 | Producing of human antii cancer senstizing lymphocyte |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2414918A1 true FR2414918A1 (fr) | 1979-08-17 |
Family
ID=15519544
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7835235A Withdrawn FR2414918A1 (fr) | 1977-12-16 | 1978-12-14 | Procede de preparation in vitro d'un agent immunotherapeutique pour le traitement du cancer |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS5484017A (fr) |
| FR (1) | FR2414918A1 (fr) |
| GB (1) | GB2010089A (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2414919A1 (fr) * | 1978-01-19 | 1979-08-17 | Jaeger Karl | Procede de preparation d'un complexe de substance active immunologique dirige contre la croissance maligne a partir de cellules |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3483252D1 (de) * | 1983-12-05 | 1990-10-25 | Asahi Chemical Ind | Verfahren zur induktion von antitumorimmunozyten, verfahren zur herstellung von antitumorimmunozyten und durch das verfahren hergestellte antitumorimmunozyten. |
| US5308626A (en) * | 1985-06-28 | 1994-05-03 | Toni N. Mariani | Lymphokine activated effector cells for antibody-dependent cellular cytotoxicity (ADCC) treatment of cancer and other diseases |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1617886A1 (de) * | 1967-03-06 | 1971-01-28 | Dr Med Karl Theurer | Verfahren zur Herstellung von Arzneimitteln mit selektivem Tropismus gegen Krebs und bestimmte Organe |
-
1977
- 1977-12-16 JP JP15148677A patent/JPS5484017A/ja active Pending
-
1978
- 1978-12-06 GB GB7847387A patent/GB2010089A/en not_active Withdrawn
- 1978-12-14 FR FR7835235A patent/FR2414918A1/fr not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1617886A1 (de) * | 1967-03-06 | 1971-01-28 | Dr Med Karl Theurer | Verfahren zur Herstellung von Arzneimitteln mit selektivem Tropismus gegen Krebs und bestimmte Organe |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2414919A1 (fr) * | 1978-01-19 | 1979-08-17 | Jaeger Karl | Procede de preparation d'un complexe de substance active immunologique dirige contre la croissance maligne a partir de cellules |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5484017A (en) | 1979-07-04 |
| GB2010089A (en) | 1979-06-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |