FR2421900A1 - Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques - Google Patents

Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques

Info

Publication number
FR2421900A1
FR2421900A1 FR7707993A FR7707993A FR2421900A1 FR 2421900 A1 FR2421900 A1 FR 2421900A1 FR 7707993 A FR7707993 A FR 7707993A FR 7707993 A FR7707993 A FR 7707993A FR 2421900 A1 FR2421900 A1 FR 2421900A1
Authority
FR
France
Prior art keywords
piperazino
indoles
preparation process
therapeutic applications
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7707993A
Other languages
English (en)
Other versions
FR2421900B1 (fr
Inventor
Andre Buzas
Jean-Marie Melon
Gilbert Lavielle
Andre Champagnac
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SAUBA LAB
Original Assignee
SAUBA LAB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SAUBA LAB filed Critical SAUBA LAB
Priority to FR7707993A priority Critical patent/FR2421900A1/fr
Priority to GB902078A priority patent/GB1570374A/en
Priority to DE19782811031 priority patent/DE2811031C2/de
Priority to ES467954A priority patent/ES467954A1/es
Publication of FR2421900A1 publication Critical patent/FR2421900A1/fr
Application granted granted Critical
Publication of FR2421900B1 publication Critical patent/FR2421900B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

Les pipérazino-3-indoles répondent à la formule :
FR7707993A 1977-03-17 1977-03-17 Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques Granted FR2421900A1 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
FR7707993A FR2421900A1 (fr) 1977-03-17 1977-03-17 Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques
GB902078A GB1570374A (en) 1977-03-17 1978-03-07 Indoles
DE19782811031 DE2811031C2 (de) 1977-03-17 1978-03-14 Piperazino-3-indole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
ES467954A ES467954A1 (es) 1977-03-17 1978-03-17 Procedimiento para preparar piperacino-3-indoles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7707993A FR2421900A1 (fr) 1977-03-17 1977-03-17 Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques

Publications (2)

Publication Number Publication Date
FR2421900A1 true FR2421900A1 (fr) 1979-11-02
FR2421900B1 FR2421900B1 (fr) 1980-10-10

Family

ID=9188218

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7707993A Granted FR2421900A1 (fr) 1977-03-17 1977-03-17 Piperazino-3-indoles, leur procede de preparation et leurs applications therapeutiques

Country Status (4)

Country Link
DE (1) DE2811031C2 (fr)
ES (1) ES467954A1 (fr)
FR (1) FR2421900A1 (fr)
GB (1) GB1570374A (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2475898A1 (fr) * 1980-02-14 1981-08-21 Andre Buzas Medicament analgesique contenant de la 1-(3'-benzofuryl)-4-benzylpiperazine et son procede de preparation
ES2063700A1 (es) * 1993-04-28 1995-01-01 Vita Invest Sa Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan.

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2524884A1 (fr) * 1982-04-07 1983-10-14 Delalande Sa Nouvelles piperazines substituees par un groupe heterocyclique du type benzotriazolyle ou indolyle, leur procede de preparation et leur application en therapeutique
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
JP2800953B2 (ja) * 1990-07-06 1998-09-21 住友製薬株式会社 新規なイミド誘導体
DK181190D0 (da) * 1990-07-30 1990-07-30 Lundbeck & Co As H 3-aryl-indol- eller 3-aryl-indazolderivater
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
NZ243065A (en) 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
WO2004106298A1 (fr) * 2003-05-30 2004-12-09 Janssen Pharmaceutica N.V. Derive d'indole a activite antipsychotique amelioree
ATE537166T1 (de) * 2006-10-27 2011-12-15 Boehringer Ingelheim Int Piperidylpropanthiole als ccr3-modulatoren
WO2008049875A1 (fr) * 2006-10-27 2008-05-02 Boehringer Ingelheim International Gmbh Nouveaux pipéridyl-propane-thiols substitués
US8536168B2 (en) * 2007-03-15 2013-09-17 Novartis Ag Benzyl and pyridinyl derivatives as modulators of the hedgehog signaling pathway
US20100041663A1 (en) 2008-07-18 2010-02-18 Novartis Ag Organic Compounds as Smo Inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1135461B (de) * 1959-05-08 1962-08-30 Knoll Ag Verfahren zur Herstellung von basisch substituierten Phthalimidinen
NL133995C (fr) * 1965-08-21
DE2138865A1 (de) * 1970-08-15 1973-02-22 Sumitomo Chemical Co 3-indolylpiperazine, verfahren zu ihrer herstellung und arzneimittel
US3751416A (en) * 1971-05-27 1973-08-07 American Cyanamid Co 3-(2-(4-phenyl-1-piperazinyl)-ethyl)indolines
FR2140260B1 (fr) * 1971-06-07 1974-08-30 Delalande Sa
BE790679A (fr) * 1971-11-03 1973-04-27 Ici Ltd Derives de l'indole
FR2191895B1 (fr) * 1972-07-17 1975-10-17 Bellon Labor Sa Roger

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2475898A1 (fr) * 1980-02-14 1981-08-21 Andre Buzas Medicament analgesique contenant de la 1-(3'-benzofuryl)-4-benzylpiperazine et son procede de preparation
EP0034521A1 (fr) * 1980-02-14 1981-08-26 André Buzas Médicament analgésique contenant de la 1-(3'benzofuryl)-4-benzylpipérazine et son procédé de préparation
ES2063700A1 (es) * 1993-04-28 1995-01-01 Vita Invest Sa Agente activo sobre el sistema nervioso central, proceso para su preparacion y composiciones farmaceuticas que lo contengan.

Also Published As

Publication number Publication date
GB1570374A (en) 1980-07-02
ES467954A1 (es) 1978-11-01
DE2811031C2 (de) 1984-11-29
FR2421900B1 (fr) 1980-10-10
DE2811031A1 (de) 1978-09-21

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Legal Events

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TP Transmission of property
ST Notification of lapse