FR2823748B1 - Tetrahydropyridyl-alkyl-benzodiazines, procede pour leur preparation et compositions pharmaceutiques les contenant - Google Patents

Tetrahydropyridyl-alkyl-benzodiazines, procede pour leur preparation et compositions pharmaceutiques les contenant

Info

Publication number
FR2823748B1
FR2823748B1 FR0105360A FR0105360A FR2823748B1 FR 2823748 B1 FR2823748 B1 FR 2823748B1 FR 0105360 A FR0105360 A FR 0105360A FR 0105360 A FR0105360 A FR 0105360A FR 2823748 B1 FR2823748 B1 FR 2823748B1
Authority
FR
France
Prior art keywords
benzodiazines
tetrahydropyridyl
alkyl
preparation
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0105360A
Other languages
English (en)
Other versions
FR2823748A1 (fr
Inventor
Marco Baroni
Bernard Bourrie
Pierre Casellas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0105360A priority Critical patent/FR2823748B1/fr
Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA
Priority to EP02727676A priority patent/EP1383762B1/fr
Priority to US10/475,460 priority patent/US7186720B2/en
Priority to JP2002583415A priority patent/JP4324382B2/ja
Priority to DE60220779T priority patent/DE60220779T2/de
Priority to PCT/FR2002/001343 priority patent/WO2002085888A1/fr
Priority to AT02727676T priority patent/ATE365162T1/de
Publication of FR2823748A1 publication Critical patent/FR2823748A1/fr
Application granted granted Critical
Publication of FR2823748B1 publication Critical patent/FR2823748B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0105360A 2001-04-20 2001-04-20 Tetrahydropyridyl-alkyl-benzodiazines, procede pour leur preparation et compositions pharmaceutiques les contenant Expired - Fee Related FR2823748B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR0105360A FR2823748B1 (fr) 2001-04-20 2001-04-20 Tetrahydropyridyl-alkyl-benzodiazines, procede pour leur preparation et compositions pharmaceutiques les contenant
US10/475,460 US7186720B2 (en) 2001-04-20 2002-04-19 Tetrahydropyridyl-alkyl-heterocycles, method for preparing the same and pharmaceutical compositions containing the same
JP2002583415A JP4324382B2 (ja) 2001-04-20 2002-04-19 テトラヒドロピリジル−アルキル−複素環、その製造方法およびそれを含む医薬組成物
DE60220779T DE60220779T2 (de) 2001-04-20 2002-04-19 Tetrahydropyridyl-alkyl-heterozykle, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die sie enthalten
EP02727676A EP1383762B1 (fr) 2001-04-20 2002-04-19 Tetrahydropyridyl-alkyl-heterocycles, procede pour leur preparation et compositions pharmaceutiques les contenants
PCT/FR2002/001343 WO2002085888A1 (fr) 2001-04-20 2002-04-19 Tetrahydropyridyl-alkyl-heterocycles, procede pour leur preparation et compositions pharmaceutiques les contenants
AT02727676T ATE365162T1 (de) 2001-04-20 2002-04-19 Tetrahydropyridyl-alkyl-heterozykle, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die sie enthalten

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0105360A FR2823748B1 (fr) 2001-04-20 2001-04-20 Tetrahydropyridyl-alkyl-benzodiazines, procede pour leur preparation et compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
FR2823748A1 FR2823748A1 (fr) 2002-10-25
FR2823748B1 true FR2823748B1 (fr) 2004-02-20

Family

ID=8862516

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0105360A Expired - Fee Related FR2823748B1 (fr) 2001-04-20 2001-04-20 Tetrahydropyridyl-alkyl-benzodiazines, procede pour leur preparation et compositions pharmaceutiques les contenant

Country Status (1)

Country Link
FR (1) FR2823748B1 (fr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3421641A1 (de) * 1984-06-09 1985-12-12 Merck Patent Gmbh, 6100 Darmstadt Indolderivate
PT100441A (pt) * 1991-05-02 1993-09-30 Smithkline Beecham Corp Pirrolidinonas, seu processo de preparacao, composicoes farmaceuticas que as contem e uso
FR2736053B1 (fr) * 1995-06-28 1997-09-19 Sanofi Sa Nouvelles 1-phenylalkyl-1,2,3,6-tetrahydropyridines
FR2762514B1 (fr) * 1997-04-29 1999-10-22 Sanofi Sa Utilisation de derives de la tetrahydropyridine pour la preparation de medicaments pour le traitement des maladies entrainant une demyelinisation
US6509351B1 (en) * 1999-10-22 2003-01-21 Sanofi-Syntelabo Phenyl- and pyridyl-tetrahydro-pyridines having TNF inhibiting activity

Also Published As

Publication number Publication date
FR2823748A1 (fr) 2002-10-25

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Effective date: 20121228