FR2823751B1 - Nouveaux composes de la famille des 3-alkyl-(4,5 diphenyl- imidazol-1-yl) et leur utilisation comme anti-inflammatoires - Google Patents

Nouveaux composes de la famille des 3-alkyl-(4,5 diphenyl- imidazol-1-yl) et leur utilisation comme anti-inflammatoires

Info

Publication number
FR2823751B1
FR2823751B1 FR0105498A FR0105498A FR2823751B1 FR 2823751 B1 FR2823751 B1 FR 2823751B1 FR 0105498 A FR0105498 A FR 0105498A FR 0105498 A FR0105498 A FR 0105498A FR 2823751 B1 FR2823751 B1 FR 2823751B1
Authority
FR
France
Prior art keywords
imidazol
diphenyl
inflammatory
family
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0105498A
Other languages
English (en)
Other versions
FR2823751A1 (fr
Inventor
Jean Baptiste Galey
Yann Mahe
Maria Dalko
Jacqueline Dumats
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
L'Oréal SA
Original Assignee
L'Oréal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0105498A priority Critical patent/FR2823751B1/fr
Application filed by L'Oréal SA filed Critical L'Oréal SA
Priority to KR1020067012891A priority patent/KR100814648B1/ko
Priority to JP2002583391A priority patent/JP2004526782A/ja
Priority to KR1020037013885A priority patent/KR100738272B1/ko
Priority to EP02738202A priority patent/EP1385828A1/fr
Priority to US10/475,654 priority patent/US20040162328A1/en
Priority to CNA028121031A priority patent/CN1649846A/zh
Priority to PCT/FR2002/001413 priority patent/WO2002085864A1/fr
Publication of FR2823751A1 publication Critical patent/FR2823751A1/fr
Application granted granted Critical
Publication of FR2823751B1 publication Critical patent/FR2823751B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR0105498A 2001-04-24 2001-04-24 Nouveaux composes de la famille des 3-alkyl-(4,5 diphenyl- imidazol-1-yl) et leur utilisation comme anti-inflammatoires Expired - Fee Related FR2823751B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR0105498A FR2823751B1 (fr) 2001-04-24 2001-04-24 Nouveaux composes de la famille des 3-alkyl-(4,5 diphenyl- imidazol-1-yl) et leur utilisation comme anti-inflammatoires
JP2002583391A JP2004526782A (ja) 2001-04-24 2002-04-24 ３−アルキル−（４，５−ジフェニル−イミダゾル−１−イル）ファミリーの化合物及び鎮静剤としてのその用途
KR1020037013885A KR100738272B1 (ko) 2001-04-24 2002-04-24 1-알킬 4,5-디페닐-이미다졸계의 화합물 및 진정제로서의 그의 용도
EP02738202A EP1385828A1 (fr) 2001-04-24 2002-04-24 Composes de la famille des 3-alkyl-(4,5 diphenyl-imizadol-1-yl) et leur utilisation comme moyen d'apaisement
KR1020067012891A KR100814648B1 (ko) 2001-04-24 2002-04-24 1-알킬 4,5-디페닐-이미다졸계의 화합물 및 진정제로서의그의 용도
US10/475,654 US20040162328A1 (en) 2001-04-24 2002-04-24 Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents
CNA028121031A CN1649846A (zh) 2001-04-24 2002-04-24 新型3－烷基(4,5－二苯基咪唑－1－基)族化合物以及其作为镇静剂的应用
PCT/FR2002/001413 WO2002085864A1 (fr) 2001-04-24 2002-04-24 Composes de la famille des 3-alkyl-(4,5 diphenyl-imidazol-1-yl) et leur utilisation comme apaisants

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0105498A FR2823751B1 (fr) 2001-04-24 2001-04-24 Nouveaux composes de la famille des 3-alkyl-(4,5 diphenyl- imidazol-1-yl) et leur utilisation comme anti-inflammatoires

Publications (2)

Publication Number Publication Date
FR2823751A1 FR2823751A1 (fr) 2002-10-25
FR2823751B1 true FR2823751B1 (fr) 2003-05-23

Family

ID=8862629

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0105498A Expired - Fee Related FR2823751B1 (fr) 2001-04-24 2001-04-24 Nouveaux composes de la famille des 3-alkyl-(4,5 diphenyl- imidazol-1-yl) et leur utilisation comme anti-inflammatoires

Country Status (7)

Country Link
US (1) US20040162328A1 (fr)
EP (1) EP1385828A1 (fr)
JP (1) JP2004526782A (fr)
KR (2) KR100814648B1 (fr)
CN (1) CN1649846A (fr)
FR (1) FR2823751B1 (fr)
WO (1) WO2002085864A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5610751B2 (ja) * 2008-12-02 2014-10-22 日本合成化学工業株式会社 金属表面処理剤ならびにイミダゾール系化合物
US12043608B1 (en) 2023-09-05 2024-07-23 King Faisal University 2-(Benzo[b]thiophen-3-yl)-1-butyl-4,5-diphenyl-1H-imidazole as an anti-inflammatory and anti-microbial compound

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2149201T3 (es) * 1992-02-11 2000-11-01 Smithkline Beecham Corp Inhibidores de coa-it y paf.
IL110296A (en) * 1993-07-16 1999-12-31 Smithkline Beecham Corp Imidazole compounds process for their preparation and pharmaceutical compositions containing them
GB9606429D0 (en) * 1996-03-27 1996-06-05 Boots Co Plc Pharmaceutical compositions
US5705145A (en) * 1996-08-21 1998-01-06 E-L Management Corp. Skin tanning compositions and method
AU8757098A (en) * 1997-06-30 1999-02-10 Ortho-Mcneil Pharmaceutical, Inc. 2-substituted imidazoles useful in the treatment of inflammatory diseases

Also Published As

Publication number Publication date
KR100738272B1 (ko) 2007-07-12
JP2004526782A (ja) 2004-09-02
CN1649846A (zh) 2005-08-03
KR20060084452A (ko) 2006-07-24
WO2002085864A1 (fr) 2002-10-31
KR20030090789A (ko) 2003-11-28
US20040162328A1 (en) 2004-08-19
EP1385828A1 (fr) 2004-02-04
KR100814648B1 (ko) 2008-03-18
FR2823751A1 (fr) 2002-10-25

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Effective date: 20091231