FR2852246B1 - Utilisation de l'oxime de cholest-4-en-3-one dans le traitement des affections du motoneurone - Google Patents

Utilisation de l'oxime de cholest-4-en-3-one dans le traitement des affections du motoneurone

Info

Publication number
FR2852246B1
FR2852246B1 FR0302992A FR0302992A FR2852246B1 FR 2852246 B1 FR2852246 B1 FR 2852246B1 FR 0302992 A FR0302992 A FR 0302992A FR 0302992 A FR0302992 A FR 0302992A FR 2852246 B1 FR2852246 B1 FR 2852246B1
Authority
FR
France
Prior art keywords
motoneurone
cholest
oxime
disorders
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0302992A
Other languages
English (en)
Other versions
FR2852246A1 (fr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0302992A priority Critical patent/FR2852246B1/fr
Application filed filed Critical
Priority to PCT/FR2004/000532 priority patent/WO2004082581A2/fr
Priority to US10/548,473 priority patent/US7858603B2/en
Priority to EP04717660A priority patent/EP1601363B1/fr
Priority to ES04717660T priority patent/ES2388669T3/es
Priority to CA2517893A priority patent/CA2517893C/fr
Priority to JP2006505701A priority patent/JP4970932B2/ja
Priority to DK04717660.7T priority patent/DK1601363T3/da
Priority to AU2004222540A priority patent/AU2004222540B2/en
Priority to PT04717660T priority patent/PT1601363E/pt
Priority to BRPI0408240-0A priority patent/BRPI0408240A/pt
Priority to PL04717660T priority patent/PL1601363T3/pl
Publication of FR2852246A1 publication Critical patent/FR2852246A1/fr
Application granted granted Critical
Publication of FR2852246B1 publication Critical patent/FR2852246B1/fr
Priority to IL170348A priority patent/IL170348A/en
Priority to US12/776,217 priority patent/US8283341B2/en
Priority to US13/591,774 priority patent/US8575138B2/en
Priority to US13/591,789 priority patent/US8354395B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0302992A 2003-03-11 2003-03-11 Utilisation de l'oxime de cholest-4-en-3-one dans le traitement des affections du motoneurone Expired - Fee Related FR2852246B1 (fr)

Priority Applications (16)

Application Number Priority Date Filing Date Title
FR0302992A FR2852246B1 (fr) 2003-03-11 2003-03-11 Utilisation de l'oxime de cholest-4-en-3-one dans le traitement des affections du motoneurone
BRPI0408240-0A BRPI0408240A (pt) 2003-03-11 2004-03-05 composto, utilização de um composto e composição farmacêutica
EP04717660A EP1601363B1 (fr) 2003-03-11 2004-03-05 Application a titre de medicaments de derives de cholest-4-en-3- one, compositions pharmaceutiques les renfermant et nouveaux derives
ES04717660T ES2388669T3 (es) 2003-03-11 2004-03-05 Aplicación como medicamentos de los dreivados de colest-4-en-3-ona, composiciones farmacéuticas que los contienen y nuevos derivados
CA2517893A CA2517893C (fr) 2003-03-11 2004-03-05 Application a titre de medicaments de derives de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, nouveaux derives et leur procede de preparation
JP2006505701A JP4970932B2 (ja) 2003-03-11 2004-03-05 コレスト−４−エン−３−オンの誘導体の医薬としての使用、これらを含む医薬組成物、新規誘導体及びそれらの製造方法
DK04717660.7T DK1601363T3 (da) 2003-03-11 2004-03-05 Anvendelse som lægemiddel af derivater af cholest-4-en-3-on, farmaceutiske sammensætninger indeholdende disse og nye derivater
AU2004222540A AU2004222540B2 (en) 2003-03-11 2004-03-05 Use of derivatives of cholest-4-en-3-one as medicaments, pharmaceutical compositions containing same, novel derivatives and preparation method thereof
PCT/FR2004/000532 WO2004082581A2 (fr) 2003-03-11 2004-03-05 Application a titre de medicaments de derives de cholest-4-en-3- one, compositions pharmaceutiques les renfermant et nouveaux derives
US10/548,473 US7858603B2 (en) 2003-03-11 2004-03-05 Use of derivatives of cholest-4-en-3-one as medicaments, pharmaceutical compositions containing same, novel derivatives and preparation method thereof
PL04717660T PL1601363T3 (pl) 2003-03-11 2004-03-05 Zastosowanie pochodnych cholest-4-en-onu jako leków, kompozycje farmaceutyczne zawierające te pochodne, nowe pochodne i sposób ich wytwarzania
PT04717660T PT1601363E (pt) 2003-03-11 2004-03-05 Aplicação como medicamentos de derivados da colest-4-en-3- ona, composições farmacêuticas que os contêm e novos derivados
IL170348A IL170348A (en) 2003-03-11 2005-08-18 Annals of Colest-4-and-3-On Oxes, Containing and Using Pharmaceutical Preparations
US12/776,217 US8283341B2 (en) 2003-03-11 2010-05-07 Use as medicaments of derivatives of cholest-4-en-3-one, pharmaceutical compositions containing them, novel derivatives and their preparation process
US13/591,774 US8575138B2 (en) 2003-03-11 2012-08-22 Method for providing neuroprotection
US13/591,789 US8354395B2 (en) 2003-03-11 2012-08-22 Method for providing neuroprotection from spinal muscular atrophy

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0302992A FR2852246B1 (fr) 2003-03-11 2003-03-11 Utilisation de l'oxime de cholest-4-en-3-one dans le traitement des affections du motoneurone

Publications (2)

Publication Number Publication Date
FR2852246A1 FR2852246A1 (fr) 2004-09-17
FR2852246B1 true FR2852246B1 (fr) 2005-07-08

Family

ID=32893204

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0302992A Expired - Fee Related FR2852246B1 (fr) 2003-03-11 2003-03-11 Utilisation de l'oxime de cholest-4-en-3-one dans le traitement des affections du motoneurone

Country Status (1)

Country Link
FR (1) FR2852246B1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2894968B1 (fr) * 2005-12-20 2008-02-22 Trophos Sa Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation
JP2019517516A (ja) * 2016-06-03 2019-06-24 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｓｍａの新規な処置

Also Published As

Publication number Publication date
FR2852246A1 (fr) 2004-09-17

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Legal Events

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CL Concession to grant licences
ST Notification of lapse

Effective date: 20141128