FR2878747B1 - Utilisation d'acide(s) gras omega-3 pour le traitement de l'hypercholesterolemie causee par un traitement anti-retroviral chez les patients infectes par le vih - Google Patents

Utilisation d'acide(s) gras omega-3 pour le traitement de l'hypercholesterolemie causee par un traitement anti-retroviral chez les patients infectes par le vih

Info

Publication number
FR2878747B1
FR2878747B1 FR0412862A FR0412862A FR2878747B1 FR 2878747 B1 FR2878747 B1 FR 2878747B1 FR 0412862 A FR0412862 A FR 0412862A FR 0412862 A FR0412862 A FR 0412862A FR 2878747 B1 FR2878747 B1 FR 2878747B1
Authority
FR
France
Prior art keywords
treatment
omega
fatty acid
infected patients
hiv infected
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0412862A
Other languages
English (en)
Other versions
FR2878747A1 (fr
Inventor
Jean Gardette
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Original Assignee
Pierre Fabre Medicament SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0412862A priority Critical patent/FR2878747B1/fr
Application filed by Pierre Fabre Medicament SA filed Critical Pierre Fabre Medicament SA
Priority to RU2007123368/15A priority patent/RU2007123368A/ru
Priority to PCT/EP2005/056431 priority patent/WO2006058920A1/fr
Priority to CA002589797A priority patent/CA2589797A1/fr
Priority to MX2007006561A priority patent/MX2007006561A/es
Priority to KR1020077015265A priority patent/KR20070089216A/ko
Priority to US11/792,060 priority patent/US20080113046A1/en
Priority to BRPI0515823-0A priority patent/BRPI0515823A/pt
Priority to EP05816108A priority patent/EP1827414A1/fr
Priority to CNA2005800412354A priority patent/CN101068542A/zh
Priority to AU2005311266A priority patent/AU2005311266A1/en
Priority to JP2007543861A priority patent/JP2008521863A/ja
Publication of FR2878747A1 publication Critical patent/FR2878747A1/fr
Application granted granted Critical
Publication of FR2878747B1 publication Critical patent/FR2878747B1/fr
Priority to IL183349A priority patent/IL183349A0/en
Priority to NO20073318A priority patent/NO20073318L/no
Priority to ZA200705392A priority patent/ZA200705392B/xx
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/60—Fish, e.g. seahorses; Fish eggs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/348—Cannabaceae
    • A61K36/3482—Cannabis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/55—Linaceae (Flax family), e.g. Linum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
FR0412862A 2004-12-03 2004-12-03 Utilisation d'acide(s) gras omega-3 pour le traitement de l'hypercholesterolemie causee par un traitement anti-retroviral chez les patients infectes par le vih Expired - Fee Related FR2878747B1 (fr)

Priority Applications (15)

Application Number Priority Date Filing Date Title
FR0412862A FR2878747B1 (fr) 2004-12-03 2004-12-03 Utilisation d'acide(s) gras omega-3 pour le traitement de l'hypercholesterolemie causee par un traitement anti-retroviral chez les patients infectes par le vih
AU2005311266A AU2005311266A1 (en) 2004-12-03 2005-12-02 Use of omega-3 fatty acid(s) for treating hypercholesterolemia caused by anti-retroviral treatment of HIV-infected patients
CA002589797A CA2589797A1 (fr) 2004-12-03 2005-12-02 Utilisation d'acide(s) gras omega-3 pour le traitement de l'hypercholesterolemie causee par un traitement anti-retroviral chez les patients infectes par le vih
MX2007006561A MX2007006561A (es) 2004-12-03 2005-12-02 Uso de acido(s) graso s) omega-3 para el tratamiento de la hipercolesterolemia causada por el tratamiento antirretroviral de los pacientes infectados con vih.
KR1020077015265A KR20070089216A (ko) 2004-12-03 2005-12-02 Ｈｉｖ―감염자의 바이러스성 치료로 인해 생기는고콜레스테롤혈증을 치료하기 위한 오메가3지방산의 사용방법
US11/792,060 US20080113046A1 (en) 2004-12-03 2005-12-02 Use of Omega-3 Fatty Acid(s) for Treating Hypercholesterolemia Caused by Anti-Retroviral Treatment of Hiv-Infected Patients
BRPI0515823-0A BRPI0515823A (pt) 2004-12-03 2005-12-02 utilização de ácido(s) graxo(s) Èmega-3 para o tratamento da hipercolesterolemia causada por um tratamento anti-retroviral nos pacientes infectados pelo hiv
EP05816108A EP1827414A1 (fr) 2004-12-03 2005-12-02 Utilisation d'acide(s) gras omega-3 pour le traitement de l'hypercholesterolemie causee par un traitement anti-retroviral chez les patients infectes par le vih
RU2007123368/15A RU2007123368A (ru) 2004-12-03 2005-12-02 Применение омега-3 жирных кислот для лечения гиперхолестеринемии, вызванной противоретровирусным лечением, у вич-инфицированных больных
PCT/EP2005/056431 WO2006058920A1 (fr) 2004-12-03 2005-12-02 Utilisation d'acide(s) gras omega-3 pour le traitement de l'hypercholesterolemie causee par un traitement anti-retroviral chez les patients infectes par le vih
JP2007543861A JP2008521863A (ja) 2004-12-03 2005-12-02 Ｈｉｖ感染患者における抗レトロウイルス治療がひき起こす高コレステロール血症の治療のためのオメガ−３脂肪酸の利用
CNA2005800412354A CN101068542A (zh) 2004-12-03 2005-12-02 Omega－3脂肪酸在治疗由HIV感染者的抗逆转录病毒治疗引起的高胆固醇血症中的用途
IL183349A IL183349A0 (en) 2004-12-03 2007-05-21 Use of omega-3 fatty acid(s) for treating hypercholesterolemia caused by anti-retroviral treatment of hiv-infected patients
NO20073318A NO20073318L (no) 2004-12-03 2007-06-27 Anvendelse av omega-3 fettsyre(r) til a behandle hyperkolesterolemi forarsaket av antiretroviral behandling av HfV-infiserte pasienter
ZA200705392A ZA200705392B (en) 2004-12-03 2007-07-03 Use of omega-3 fatty acid(s) for treating hypercholesterolemia caused by anti-retroviral treatment of HIV-infected patients

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0412862A FR2878747B1 (fr) 2004-12-03 2004-12-03 Utilisation d'acide(s) gras omega-3 pour le traitement de l'hypercholesterolemie causee par un traitement anti-retroviral chez les patients infectes par le vih

Publications (2)

Publication Number Publication Date
FR2878747A1 FR2878747A1 (fr) 2006-06-09
FR2878747B1 true FR2878747B1 (fr) 2007-03-30

Family

ID=34952290

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0412862A Expired - Fee Related FR2878747B1 (fr) 2004-12-03 2004-12-03 Utilisation d'acide(s) gras omega-3 pour le traitement de l'hypercholesterolemie causee par un traitement anti-retroviral chez les patients infectes par le vih

Country Status (15)

Country Link
US (1) US20080113046A1 (fr)
EP (1) EP1827414A1 (fr)
JP (1) JP2008521863A (fr)
KR (1) KR20070089216A (fr)
CN (1) CN101068542A (fr)
AU (1) AU2005311266A1 (fr)
BR (1) BRPI0515823A (fr)
CA (1) CA2589797A1 (fr)
FR (1) FR2878747B1 (fr)
IL (1) IL183349A0 (fr)
MX (1) MX2007006561A (fr)
NO (1) NO20073318L (fr)
RU (1) RU2007123368A (fr)
WO (1) WO2006058920A1 (fr)
ZA (1) ZA200705392B (fr)

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US8343753B2 (en) 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
EP3187182B1 (fr) 2008-09-02 2021-03-03 Amarin Pharmaceuticals Ireland Limited Compositions pharmaceutiques contenant de l'acide eicosapentaénoïque et de l'acide nicotinique, et leurs procédés d'utilisation
RU2505292C2 (ru) 2009-02-10 2014-01-27 Амарин Фармасьютикалз Айрлэнд Лимитед Способы лечения гипертриглицеридемии
CN107233337A (zh) 2009-04-29 2017-10-10 阿马里纳药物爱尔兰有限公司 含有epa和心血管剂的药物组合物以及使用其的方法
AU2014200070B2 (en) * 2009-04-29 2016-06-16 Amarin Pharmaceuticals Ireland Limited Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
AU2016203375B2 (en) * 2009-04-29 2017-11-30 Amarin Pharmaceuticals Ireland Limited Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
MX377553B (es) 2009-04-29 2025-03-10 Amarin Pharma Inc Composicion farmaceutica estable y metodos de uso de la misma.
BRPI1011883A2 (pt) 2009-06-15 2016-09-13 Amarin Pharma Inc uso de composições para redução de triglicerídeos sem elevar os níveis de o ldl-c em um paciente sob o tratamento concomitante com estatina
NZ599061A (en) 2009-09-23 2014-05-30 Amarin Pharmaceuticals Ie Ltd Pharmaceutical composition comprising omega-3 fatty acid and hydroxy-derivative of a statin and methods of using same
NZ599618A (en) 2009-10-30 2014-08-29 Tharos Ltd Solvent-free process for obtaining phospholipids and neutral enriched krill oils
CN103096904B (zh) * 2010-09-01 2016-03-09 日本水产株式会社 酒精性伤害缓解剂
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US11712429B2 (en) 2010-11-29 2023-08-01 Amarin Pharmaceuticals Ireland Limited Low eructation composition and methods for treating and/or preventing cardiovascular disease in a subject with fish allergy/hypersensitivity
WO2013070735A1 (fr) 2011-11-07 2013-05-16 Amarin Pharmaceuticals Ireland Limited Méthodes de traitement de l'hypertriglycéridémie
US11291643B2 (en) 2011-11-07 2022-04-05 Amarin Pharmaceuticals Ireland Limited Methods of treating hypertriglyceridemia
EP2800469B1 (fr) 2012-01-06 2021-08-25 Amarin Pharmaceuticals Ireland Limited Compositions et procédés pour abaisser les taux de crp à haute sensibilité (hs-crp) chez un sujet
WO2013192109A1 (fr) 2012-06-17 2013-12-27 Matinas Biopharma, Inc. Compositions d'acide pentanoïque oméga-3 et leurs procédés d'utilisation
US9603826B2 (en) 2012-06-29 2017-03-28 Amarin Pharmaceuticals Ireland Limited Methods of reducing the risk of a cardiovascular event in a subject on statin therapy
MX2015005235A (es) * 2012-10-23 2015-12-03 Univ Deakin Metodo para reducir trigliceridos.
WO2014074552A2 (fr) 2012-11-06 2014-05-15 Amarin Pharmaceuticals Ireland Limited Compositions et procédés pour diminuer les triglycérides sans augmenter les taux de ldl-c chez un sujet traité en même temps par la statine
US20140187633A1 (en) 2012-12-31 2014-07-03 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing nonalcoholic steatohepatitis and/or primary biliary cirrhosis
US9814733B2 (en) 2012-12-31 2017-11-14 A,arin Pharmaceuticals Ireland Limited Compositions comprising EPA and obeticholic acid and methods of use thereof
US9452151B2 (en) 2013-02-06 2016-09-27 Amarin Pharmaceuticals Ireland Limited Methods of reducing apolipoprotein C-III
US9624492B2 (en) 2013-02-13 2017-04-18 Amarin Pharmaceuticals Ireland Limited Compositions comprising eicosapentaenoic acid and mipomersen and methods of use thereof
US9662307B2 (en) 2013-02-19 2017-05-30 The Regents Of The University Of Colorado Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof
US9283201B2 (en) 2013-03-14 2016-03-15 Amarin Pharmaceuticals Ireland Limited Compositions and methods for treating or preventing obesity in a subject in need thereof
US20140271841A1 (en) 2013-03-15 2014-09-18 Amarin Pharmaceuticals Ireland Limited Pharmaceutical composition comprising eicosapentaenoic acid and derivatives thereof and a statin
US10966968B2 (en) 2013-06-06 2021-04-06 Amarin Pharmaceuticals Ireland Limited Co-administration of rosiglitazone and eicosapentaenoic acid or a derivative thereof
US20150065572A1 (en) 2013-09-04 2015-03-05 Amarin Pharmaceuticals Ireland Limited Methods of treating or preventing prostate cancer
US9585859B2 (en) 2013-10-10 2017-03-07 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides without raising LDL-C levels in a subject on concomitant statin therapy
US10561631B2 (en) 2014-06-11 2020-02-18 Amarin Pharmaceuticals Ireland Limited Methods of reducing RLP-C
WO2015195662A1 (fr) 2014-06-16 2015-12-23 Amarin Pharmaceuticals Ireland Limited Procédés de réduction ou de prévention de l'oxydation des ldl petites et denses ou des acides gras polyinsaturés membranaires
US10406130B2 (en) 2016-03-15 2019-09-10 Amarin Pharmaceuticals Ireland Limited Methods of reducing or preventing oxidation of small dense LDL or membrane polyunsaturated fatty acids
US10966951B2 (en) 2017-05-19 2021-04-06 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject having reduced kidney function
US11058661B2 (en) 2018-03-02 2021-07-13 Amarin Pharmaceuticals Ireland Limited Compositions and methods for lowering triglycerides in a subject on concomitant statin therapy and having hsCRP levels of at least about 2 mg/L
MA50490A (fr) 2018-09-24 2020-09-02 Amarin Pharmaceuticals Ie Ltd Procédés de réduction du risque d'événements cardiovasculaires chez un sujet
CA3160676A1 (fr) 2019-11-12 2021-05-20 Amarin Pharmaceuticals Ireland Limited Procedes de reduction du risque d'evenements cardiovasculaires chez un sujet souffrant d'une fibrillation auriculaire et/ou d'un flutter auriculaire
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US8017651B2 (en) * 2002-11-22 2011-09-13 Bionexus, Ltd. Compositions and methods for the treatment of HIV-associated fat maldistribution and hyperlipidemia

Also Published As

Publication number Publication date
BRPI0515823A (pt) 2008-08-05
FR2878747A1 (fr) 2006-06-09
ZA200705392B (en) 2008-11-26
CN101068542A (zh) 2007-11-07
CA2589797A1 (fr) 2006-06-08
AU2005311266A1 (en) 2006-06-08
MX2007006561A (es) 2007-06-15
KR20070089216A (ko) 2007-08-30
US20080113046A1 (en) 2008-05-15
IL183349A0 (en) 2008-04-13
NO20073318L (no) 2007-06-27
JP2008521863A (ja) 2008-06-26
WO2006058920A1 (fr) 2006-06-08
RU2007123368A (ru) 2009-01-10
EP1827414A1 (fr) 2007-09-05

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