FR2902010B1 - Utilisation de la 1,7 dimethylxanthine pour la fabrication d'un medicament psychoanaleptique non anxiogene destine au traitement d'un trouble neuropsychiatrique - Google Patents

Utilisation de la 1,7 dimethylxanthine pour la fabrication d'un medicament psychoanaleptique non anxiogene destine au traitement d'un trouble neuropsychiatrique

Info

Publication number
FR2902010B1
FR2902010B1 FR0605189A FR0605189A FR2902010B1 FR 2902010 B1 FR2902010 B1 FR 2902010B1 FR 0605189 A FR0605189 A FR 0605189A FR 0605189 A FR0605189 A FR 0605189A FR 2902010 B1 FR2902010 B1 FR 2902010B1
Authority
FR
France
Prior art keywords
psychoanaleptic
anxiogenic
dimethylxanthine
medicament
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0605189A
Other languages
English (en)
Other versions
FR2902010A1 (fr
Inventor
Jean Costentin
Lucilla Mansuy
Pierre Sokoloff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre Medicament SA
Universite de Rouen
Original Assignee
Pierre Fabre Medicament SA
Universite de Rouen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre Medicament SA, Universite de Rouen filed Critical Pierre Fabre Medicament SA
Priority to FR0605189A priority Critical patent/FR2902010B1/fr
Priority to TW096120502A priority patent/TW200815013A/zh
Priority to JP2009514766A priority patent/JP2009539921A/ja
Priority to EP07730023A priority patent/EP2026812A1/fr
Priority to CA002654891A priority patent/CA2654891A1/fr
Priority to US12/304,377 priority patent/US20090325984A1/en
Priority to PCT/EP2007/055668 priority patent/WO2007144315A1/fr
Priority to ARP070102566A priority patent/AR061446A1/es
Publication of FR2902010A1 publication Critical patent/FR2902010A1/fr
Application granted granted Critical
Publication of FR2902010B1 publication Critical patent/FR2902010B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/34—Tobacco-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Addiction (AREA)
  • Epidemiology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR0605189A 2006-06-12 2006-06-12 Utilisation de la 1,7 dimethylxanthine pour la fabrication d'un medicament psychoanaleptique non anxiogene destine au traitement d'un trouble neuropsychiatrique Expired - Fee Related FR2902010B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR0605189A FR2902010B1 (fr) 2006-06-12 2006-06-12 Utilisation de la 1,7 dimethylxanthine pour la fabrication d'un medicament psychoanaleptique non anxiogene destine au traitement d'un trouble neuropsychiatrique
TW096120502A TW200815013A (en) 2006-06-12 2007-06-07 Use of 1,7-dimethylxanthine for the manufacture of a non-anxiogenic psychoanaleptic drug for the treatment of a neuropsychiatric disorder
EP07730023A EP2026812A1 (fr) 2006-06-12 2007-06-08 Utilisation de 1,7-diméthylxanthine pour la fabrication d'un médicament psychoanaleptique non anxiogène pour le traitement d'un trouble neuropsychiatrique
CA002654891A CA2654891A1 (fr) 2006-06-12 2007-06-08 Utilisation de 1,7-dimethylxanthine pour la fabrication d'un medicament psychoanaleptique non anxiogene pour le traitement d'un trouble neuropsychiatrique
JP2009514766A JP2009539921A (ja) 2006-06-12 2007-06-08 神経精神障害の治療用の非不安誘発性精神賦活薬の製造のための１，７−ジメチルキサンチンの使用
US12/304,377 US20090325984A1 (en) 2006-06-12 2007-06-08 Use of 1,7-dimethylxanthine for the manufacture of a non-anxiogenic psychoanaleptic drug for the treatment of a neuropsychiatric disorder
PCT/EP2007/055668 WO2007144315A1 (fr) 2006-06-12 2007-06-08 Utilisation de 1,7-diméthylxanthine pour la fabrication d'un médicament psychoanaleptique non anxiogène pour le traitement d'un trouble neuropsychiatrique
ARP070102566A AR061446A1 (es) 2006-06-12 2007-06-12 Utilizacion de la 1,7 -dimetilxantina para la fabricacion de un medicamento psicoanaleptico no ansiogeno destinado al tratamiento de un trastorno neuropsiquiatrico

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0605189A FR2902010B1 (fr) 2006-06-12 2006-06-12 Utilisation de la 1,7 dimethylxanthine pour la fabrication d'un medicament psychoanaleptique non anxiogene destine au traitement d'un trouble neuropsychiatrique

Publications (2)

Publication Number Publication Date
FR2902010A1 FR2902010A1 (fr) 2007-12-14
FR2902010B1 true FR2902010B1 (fr) 2008-08-22

Family

ID=37592447

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0605189A Expired - Fee Related FR2902010B1 (fr) 2006-06-12 2006-06-12 Utilisation de la 1,7 dimethylxanthine pour la fabrication d'un medicament psychoanaleptique non anxiogene destine au traitement d'un trouble neuropsychiatrique

Country Status (8)

Country Link
US (1) US20090325984A1 (fr)
EP (1) EP2026812A1 (fr)
JP (1) JP2009539921A (fr)
AR (1) AR061446A1 (fr)
CA (1) CA2654891A1 (fr)
FR (1) FR2902010B1 (fr)
TW (1) TW200815013A (fr)
WO (1) WO2007144315A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104968326A (zh) * 2012-10-24 2015-10-07 莱福基因有限公司 以咖啡因和副黄嘌呤来分解脂肪的瘦身组合物
US12533346B2 (en) 2016-04-19 2026-01-27 Axcess Global Sciences, Llc Administration of berberine metabolites
US12599579B2 (en) 2016-04-19 2026-04-14 Axcess Global Sciences, Llc Compositions and compounds containing ketone bodies and/or ketone body precursors and one or more amino acids
US12496283B2 (en) 2016-04-19 2025-12-16 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
US12521378B2 (en) 2016-04-19 2026-01-13 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate salt blend and related compounds in humans
US12109182B2 (en) 2016-04-19 2024-10-08 Axcess Global Sciences, Llc Administration of R-beta-hydroxybutyrate and related compounds in humans
US20230346721A1 (en) 2018-04-18 2023-11-02 Axcess Global Sciences, Llc Beta-hydroxybutyric acid compositions and methods for delivery of ketone bodies
US12329734B2 (en) 2017-12-19 2025-06-17 Axcess Global Sciences, Llc Use of S-beta-hydroxybutyrate compounds for induction and maintenance of flow
US12472200B2 (en) 2019-05-15 2025-11-18 Axcess Global Sciences, Llc Autobiotic compositions and method for promoting healthy gut microbiome
US12167993B2 (en) 2019-06-21 2024-12-17 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
US11969430B1 (en) * 2023-03-10 2024-04-30 Axcess Global Sciences, Llc Compositions containing paraxanthine and beta-hydroxybutyrate or precursor for increasing neurological and physiological performance
US11950616B2 (en) 2019-06-21 2024-04-09 Axcess Global Sciences, Llc Non-vasoconstricting energy-promoting compositions containing ketone bodies
JP2023513457A (ja) * 2020-01-23 2023-03-31 インジニアス イングリーディエンツ，エルピー パラキサンチンをベースにした生物活性組成物およびそれを使用する方法
WO2022056190A2 (fr) * 2020-09-14 2022-03-17 Lennham Pharmaceuticals, Inc. Paraxanthine deutérée et ses utilisations
US12194046B2 (en) 2021-03-09 2025-01-14 Lennham Pharmaceuticals, Inc. D9-caffeine compositions and uses thereof
AU2022245394A1 (en) * 2021-03-26 2023-10-12 Px Ing, Llc The use of paraxanthine to reduce exercise-induced mental fatigue
CA3213575A1 (fr) * 2021-03-31 2022-10-06 Ralf Jager Utilisation de paraxanthine pour ameliorer les performances chez les joueurs de jeux videos
EP4329632A4 (fr) 2021-04-29 2025-04-16 Rarebird, Inc. Compositions et leurs procédés de production
KR20240057401A (ko) * 2021-07-27 2024-05-02 피엑스 아이엔지, 엘엘씨 파라잔틴-기반 카페인 대용 조성물 및 느린 카페인 대사자에서의 이의 사용 방법
WO2023064425A1 (fr) * 2021-10-12 2023-04-20 Ingenious Ingredients, LP Compositions de dileucine et leurs procédés d'utilisation pour la perte de graisse
WO2023097091A1 (fr) * 2021-11-28 2023-06-01 Ingenious Ingredients, LP Compositions à base de paraxanthine pour améliorer la fonction musculaire, la signalisation d'oxyde nitrique et/ou les niveaux de glycogène musculaire
AU2024230915A1 (en) * 2023-03-09 2025-10-09 Ingenious Ingredients, LP Dileucine compositions and methods of use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20070058022A (ko) * 2000-04-26 2007-06-07 에자이 알앤드디 매니지먼트 가부시키가이샤 배변을 촉진하는 의약 조성물
ATE433993T1 (de) * 2003-02-26 2009-07-15 Univ Johns Hopkins Modulatorische verbindungen und verfahren für glutamattransport
US7960544B2 (en) * 2005-12-16 2011-06-14 Ironwood Pharmaceuticals, Inc. Useful indole compounds
EP1998789A4 (fr) * 2006-02-28 2009-04-22 Metabolon Inc Biomarqueurs pour sclérose latérale amyotrophique

Also Published As

Publication number Publication date
US20090325984A1 (en) 2009-12-31
CA2654891A1 (fr) 2007-12-21
FR2902010A1 (fr) 2007-12-14
TW200815013A (en) 2008-04-01
WO2007144315A1 (fr) 2007-12-21
JP2009539921A (ja) 2009-11-19
EP2026812A1 (fr) 2009-02-25
AR061446A1 (es) 2008-08-27

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Effective date: 20140228