FR2928372B1 - Procede de synthese peptidique - Google Patents

Procede de synthese peptidique

Info

Publication number
FR2928372B1
FR2928372B1 FR0851513A FR0851513A FR2928372B1 FR 2928372 B1 FR2928372 B1 FR 2928372B1 FR 0851513 A FR0851513 A FR 0851513A FR 0851513 A FR0851513 A FR 0851513A FR 2928372 B1 FR2928372 B1 FR 2928372B1
Authority
FR
France
Prior art keywords
synthesis method
peptide synthesis
peptide
synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0851513A
Other languages
English (en)
Other versions
FR2928372A1 (fr
Inventor
Roland Callens
Laurent Jeannin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Corden Pharma Brussels SA
Original Assignee
Solvay SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0851513A priority Critical patent/FR2928372B1/fr
Application filed by Solvay SA filed Critical Solvay SA
Priority to PCT/EP2009/052677 priority patent/WO2009112437A1/fr
Priority to CN2009801083992A priority patent/CN101970453A/zh
Priority to AU2009224802A priority patent/AU2009224802C1/en
Priority to US12/921,413 priority patent/US20110105722A1/en
Priority to EP09720836A priority patent/EP2262824A1/fr
Priority to JP2010550148A priority patent/JP2011513456A/ja
Priority to CA2717186A priority patent/CA2717186A1/fr
Publication of FR2928372A1 publication Critical patent/FR2928372A1/fr
Application granted granted Critical
Publication of FR2928372B1 publication Critical patent/FR2928372B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR0851513A 2008-03-10 2008-03-10 Procede de synthese peptidique Expired - Fee Related FR2928372B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR0851513A FR2928372B1 (fr) 2008-03-10 2008-03-10 Procede de synthese peptidique
CN2009801083992A CN101970453A (zh) 2008-03-10 2009-03-06 使用n-羧酸酐(unca)的肽合成方法
AU2009224802A AU2009224802C1 (en) 2008-03-10 2009-03-06 Peptide synthesis method using N-carboxyanhydride (UNCA)
US12/921,413 US20110105722A1 (en) 2008-03-10 2009-03-06 Peptide synthesis method using n-carboxyanhydride (UNCA)
PCT/EP2009/052677 WO2009112437A1 (fr) 2008-03-10 2009-03-06 Procédé de synthèse de peptides utilisant un n-carboxyanhydride (unca)
EP09720836A EP2262824A1 (fr) 2008-03-10 2009-03-06 Procédé de synthèse de peptides utilisant un n-carboxyanhydride (unca)
JP2010550148A JP2011513456A (ja) 2008-03-10 2009-03-06 Ｎ−カルボン酸無水物（ｕｎｃａ）を使用するペプチド合成方法
CA2717186A CA2717186A1 (fr) 2008-03-10 2009-03-06 Procede de synthese de peptides utilisant un n-carboxyanhydride (unca)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0851513A FR2928372B1 (fr) 2008-03-10 2008-03-10 Procede de synthese peptidique

Publications (2)

Publication Number Publication Date
FR2928372A1 FR2928372A1 (fr) 2009-09-11
FR2928372B1 true FR2928372B1 (fr) 2010-12-31

Family

ID=39970965

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0851513A Expired - Fee Related FR2928372B1 (fr) 2008-03-10 2008-03-10 Procede de synthese peptidique

Country Status (8)

Country Link
US (1) US20110105722A1 (fr)
EP (1) EP2262824A1 (fr)
JP (1) JP2011513456A (fr)
CN (1) CN101970453A (fr)
AU (1) AU2009224802C1 (fr)
CA (1) CA2717186A1 (fr)
FR (1) FR2928372B1 (fr)
WO (1) WO2009112437A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3500286A4 (fr) * 2016-08-16 2020-03-25 Stealth BioTherapeutics Corp Synthèse d'échelle d'elamipretide à base de n-carboxyanhydride
CN109422797B (zh) * 2017-08-30 2023-12-19 上海科胜药物研发有限公司 一种赖诺普利中间体的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946942A (en) * 1988-03-11 1990-08-07 Bioresearch, Inc. Urethane-protected amino acid-N-carboxyanhydrides
SE9903291D0 (sv) * 1999-09-15 1999-09-15 Astra Ab New process
FR2815962B1 (fr) * 2000-10-30 2003-03-07 Isochem Sa Procede de preparation des n-carboxyanhydrides
FR2828195B1 (fr) * 2001-05-31 2003-12-26 Isochem Sa Procede de preparation des n-carboxyanhydrides
FR2846326A1 (fr) * 2002-10-29 2004-04-30 Isochem Sa Procede de purification des n-carboxyanhydrides
FR2858976B1 (fr) * 2003-08-22 2006-02-10 Isochem Sa Procede d'obtention de n-carboxyanhydrides d'alpha-aminoacides a protection urethane

Also Published As

Publication number Publication date
CA2717186A1 (fr) 2009-09-17
US20110105722A1 (en) 2011-05-05
EP2262824A1 (fr) 2010-12-22
AU2009224802A1 (en) 2009-09-17
WO2009112437A1 (fr) 2009-09-17
FR2928372A1 (fr) 2009-09-11
JP2011513456A (ja) 2011-04-28
AU2009224802C1 (en) 2014-11-27
CN101970453A (zh) 2011-02-09
AU2009224802B2 (en) 2014-07-31

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Legal Events

Date Code Title Description
TP Transmission of property

Owner name: PEPTISYNTHA SA, BE

Effective date: 20131003

ST Notification of lapse

Effective date: 20151130