FR2934953B1 - Nanoemulsions de nanocristaux - Google Patents

Nanoemulsions de nanocristaux

Info

Publication number
FR2934953B1
FR2934953B1 FR0855588A FR0855588A FR2934953B1 FR 2934953 B1 FR2934953 B1 FR 2934953B1 FR 0855588 A FR0855588 A FR 0855588A FR 0855588 A FR0855588 A FR 0855588A FR 2934953 B1 FR2934953 B1 FR 2934953B1
Authority
FR
France
Prior art keywords
nanoemulsions
crystals
nano
crystals nanoemulsions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR0855588A
Other languages
English (en)
Other versions
FR2934953A1 (fr
Inventor
Nogues Isabelle Texier
Toufic Daou
Mathieu Goutayer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0855588A priority Critical patent/FR2934953B1/fr
Application filed by Commissariat a lEnergie Atomique CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to US13/058,849 priority patent/US9180210B2/en
Priority to JP2011522519A priority patent/JP5642676B2/ja
Priority to CN200980134621.6A priority patent/CN102143764B/zh
Priority to PCT/EP2009/060534 priority patent/WO2010018222A1/fr
Priority to CA2733959A priority patent/CA2733959C/fr
Priority to EP09781838.9A priority patent/EP2318052B1/fr
Publication of FR2934953A1 publication Critical patent/FR2934953A1/fr
Application granted granted Critical
Publication of FR2934953B1 publication Critical patent/FR2934953B1/fr
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0065—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle
    • A61K49/0067—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the luminescent/fluorescent agent having itself a special physical form, e.g. gold nanoparticle quantum dots, fluorescent nanocrystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
    • A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
    • A61K49/0076—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
    • A61K49/0078—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion microemulsion, nanoemulsion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Luminescent Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR0855588A 2008-08-14 2008-08-14 Nanoemulsions de nanocristaux Active FR2934953B1 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
FR0855588A FR2934953B1 (fr) 2008-08-14 2008-08-14 Nanoemulsions de nanocristaux
JP2011522519A JP5642676B2 (ja) 2008-08-14 2009-08-14 ナノ結晶のナノエマルション
CN200980134621.6A CN102143764B (zh) 2008-08-14 2009-08-14 纳米晶体纳米乳剂
PCT/EP2009/060534 WO2010018222A1 (fr) 2008-08-14 2009-08-14 Nano-émulsion de nanocristaux
US13/058,849 US9180210B2 (en) 2008-08-14 2009-08-14 Nanocrystal nano-emulsion
CA2733959A CA2733959C (fr) 2008-08-14 2009-08-14 Nano-emulsion de nanocristaux
EP09781838.9A EP2318052B1 (fr) 2008-08-14 2009-08-14 Nano-émulsion de nanocristaux

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0855588A FR2934953B1 (fr) 2008-08-14 2008-08-14 Nanoemulsions de nanocristaux

Publications (2)

Publication Number Publication Date
FR2934953A1 FR2934953A1 (fr) 2010-02-19
FR2934953B1 true FR2934953B1 (fr) 2011-01-21

Family

ID=40404065

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0855588A Active FR2934953B1 (fr) 2008-08-14 2008-08-14 Nanoemulsions de nanocristaux

Country Status (7)

Country Link
US (1) US9180210B2 (fr)
EP (1) EP2318052B1 (fr)
JP (1) JP5642676B2 (fr)
CN (1) CN102143764B (fr)
CA (1) CA2733959C (fr)
FR (1) FR2934953B1 (fr)
WO (1) WO2010018222A1 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2934954B1 (fr) 2008-08-14 2011-07-22 Commissariat Energie Atomique Emulsion fluorescente de vert d'indocyanine
FR2934955B1 (fr) 2008-08-14 2011-07-08 Commissariat Energie Atomique Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions
FR2968999B1 (fr) 2010-12-20 2013-01-04 Guerbet Sa Nanoemulsion de chelate pour irm
WO2012109755A1 (fr) * 2011-02-16 2012-08-23 The Governing Council Of The University Of Toronto Particules à base d'ester gras et leurs procédés de préparation et d'utilisation
FR2980364B1 (fr) 2011-09-26 2018-08-31 Guerbet Nanoemulsions et leur utilisation comme agents de contraste
FR2991196B1 (fr) * 2012-05-29 2014-06-27 Capsum Nanoparticules ciblantes pour une application biologique
FR2998899B1 (fr) * 2012-11-30 2015-07-17 Commissariat Energie Atomique Methode de criblage a haut-debit pour l'identification de biomarqueurs, cibles therapeutiques ou d'agents therapeutiques
CN105188399A (zh) * 2013-03-15 2015-12-23 帝斯曼知识产权资产管理有限公司 固体脂质纳米颗粒（ii）
JP6492625B2 (ja) * 2014-12-22 2019-04-03 三菱マテリアル株式会社 赤外線遮蔽積層体及びこれを用いた赤外線遮蔽材
CN109773207B (zh) * 2019-02-01 2021-11-12 西南大学 采用水包油纳米乳液制备分支状金纳米颗粒的方法

Family Cites Families (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78929A0 (en) 1985-07-29 1986-09-30 Abbott Lab Microemulsion compositions for parenteral administration
US4906100A (en) 1988-05-13 1990-03-06 University Of Cincinnati Method of detecting adriamycin (doxorubicin) or daunomycin in the environment
ATE94057T1 (de) 1988-12-20 1993-09-15 Medicontrol Corp Durch hitze dehydratisierte emulsionen.
CH677886A5 (fr) 1989-06-26 1991-07-15 Hans Georg Prof Dr Weder
JP2785981B2 (ja) 1989-11-20 1998-08-13 株式会社資生堂 乳化組成物
GB2251381B (en) 1990-07-19 1995-01-25 Charwell Pharma Emulsified fluorescein diester diagnostic compositions
US5403575A (en) 1991-12-12 1995-04-04 Hemagen/Pfc Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of using them
FR2685636B1 (fr) 1991-12-31 1995-03-24 Gattefosse Ets Sa Excipient pour suppositoire constitue par une microemulsion et procede pour le fabriquer.
IL101007A (en) 1992-02-18 1997-08-14 Pharmos Ltd Dry stable compositions prepared by lyophilization
IL101387A (en) 1992-03-26 1999-11-30 Pharmos Ltd Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets
US5464696A (en) 1992-08-13 1995-11-07 Bracco International B.V. Particles for NMR imaging
JPH08506081A (ja) 1993-02-12 1996-07-02 ファーモス コーポレイション サブミクロン・エマルジョンの調製のための乾燥組成物
CA2091152C (fr) 1993-03-05 2005-05-03 Kirsten Westesen Particules lipidiques solides, particules d'agents bioactifs, et methode de preparation et d'utilisation
US6113921A (en) 1993-03-23 2000-09-05 Pharmos Corp. Topical and transdermal delivery system utilizing submicron oil spheres
FR2721210B1 (fr) 1994-06-17 1996-08-02 Oreal Composition de nettoyage contenant des grains lipidiques.
US6540981B2 (en) 1997-12-04 2003-04-01 Amersham Health As Light imaging contrast agents
WO1998048846A1 (fr) 1997-04-29 1998-11-05 Nycomed Imaging As Agents de contraste utilises dans des techniques d'imagerie basees sur la lumiere
DE69820867T2 (de) 1997-04-29 2004-11-18 Amersham Health As Lichtbilderzeugungskontrastmitteln
GB9712525D0 (en) 1997-06-16 1997-08-20 Nycomed Imaging As Method
GB9721746D0 (en) 1997-10-15 1997-12-10 Panos Therapeutics Limited Compositions
US5976502A (en) 1997-10-21 1999-11-02 Gholam A. Peyman Method of visualizing particles and blood cells containing a fluorescent lipophilic dye in the retina and choroid of the eye
US6123923A (en) 1997-12-18 2000-09-26 Imarx Pharmaceutical Corp. Optoacoustic contrast agents and methods for their use
TW537894B (en) 1998-05-26 2003-06-21 Novartis Ag A spontaneously dispersible pharmaceutical composition comprising a piperidine substance P antagonist
DE19852245A1 (de) 1998-11-12 2000-05-18 Asat Ag Applied Science & Tech 5-Aminolävulinsäure-Nanoemulsion
FR2787326B1 (fr) 1998-12-17 2001-01-26 Oreal Nanoemulsion a base d'esters gras de glycerol, et ses utilisations dans les domaines cosmetique, dermatologique et/ou ophtalmologique
FR2788007B1 (fr) 1999-01-05 2001-02-09 Oreal Nanoemulsion a base de copolymeres blocs d'oxyde d'ethylene et d'oxyde de propylene, et ses utilisations dans les domaines cosmetique, dermatologique et/ou ophtalmologique
US20020102301A1 (en) 2000-01-13 2002-08-01 Joseph Schwarz Pharmaceutical solid self-emulsifying composition for sustained delivery of biologically active compounds and the process for preparation thereof
FR2805761B1 (fr) 2000-03-02 2002-08-30 Mainelab Nanocapsules lipidiques, procede de preparation et utilisation comme medicament
AU2002357012A1 (en) * 2001-11-27 2003-06-10 Transform Pharmaceuticals, Inc. Oral pharmaceutical formulations comprising paclitaxel, derivatives and methods of administration thereof
AU2004263136A1 (en) * 2003-08-08 2005-02-17 Barnes-Jewish Hospital Emulsion particles for imaging and therapy and methods of use thereof
FR2860717B1 (fr) 2003-10-13 2006-02-03 Ethypharm Sa Compositions de particules lipidiques solides monodisperses
FR2861986B1 (fr) * 2003-11-07 2007-12-14 Oreal Composition de maquillage comprenant une emulsion
EP1563851A1 (fr) 2004-02-17 2005-08-17 Yissum Research Development Company of the Hebrew University of Jerusalem Emulsions cationiques ciblées avec des anticorps pour la livraison de drogues
CN1676125A (zh) 2004-03-31 2005-10-05 张昊 含有紫杉碱类或难溶药物的纳米级乳剂
US20050255044A1 (en) 2004-05-14 2005-11-17 Lomnes Stephen J Contrast agent for combined modality imaging and methods and systems thereof
US8557861B2 (en) 2004-09-28 2013-10-15 Mast Therapeutics, Inc. Low oil emulsion compositions for delivering taxoids and other insoluble drugs
ITMI20050218A1 (it) 2005-02-15 2006-08-16 Maycos Italiana Di Comini Miro Nanoemulsioni comprendenti lipoamminoacidi monogliceridi digliceridi poligliceridi degli acidi grassi
ATE382677T1 (de) 2005-02-18 2008-01-15 Gnosis Spa Verfahren zur herstellung von hefe-mikrokapseln
US20060222716A1 (en) 2005-04-01 2006-10-05 Joseph Schwarz Colloidal solid lipid vehicle for pharmaceutical use
US20060257493A1 (en) 2005-04-28 2006-11-16 Amiji Mansoor M Nanoparticulate delivery systems for treating multi-drug resistance
US20070148194A1 (en) 2005-11-29 2007-06-28 Amiji Mansoor M Novel nanoemulsion formulations
WO2008102065A1 (fr) 2007-02-14 2008-08-28 Commissariat A L'energie Atomique Emulsions fluorescentes pour l'imagerie optique
FR2934954B1 (fr) 2008-08-14 2011-07-22 Commissariat Energie Atomique Emulsion fluorescente de vert d'indocyanine
FR2935001B1 (fr) 2008-08-14 2011-12-30 Commissariat Energie Atomique Emulsion fluorescente
FR2934955B1 (fr) 2008-08-14 2011-07-08 Commissariat Energie Atomique Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions

Also Published As

Publication number Publication date
WO2010018222A1 (fr) 2010-02-18
US9180210B2 (en) 2015-11-10
US20110274622A1 (en) 2011-11-10
CN102143764B (zh) 2015-03-11
EP2318052A1 (fr) 2011-05-11
JP2011530573A (ja) 2011-12-22
EP2318052B1 (fr) 2018-02-21
CA2733959A1 (fr) 2010-02-18
JP5642676B2 (ja) 2014-12-17
FR2934953A1 (fr) 2010-02-19
CN102143764A (zh) 2011-08-03
CA2733959C (fr) 2016-11-29

Similar Documents

Publication Publication Date Title
BRPI0922158A2 (pt) nanoemulsões
DK2222340T3 (da) Nanoemulsioner
BRPI0921327A2 (pt) Combinação de herbicida-protetor
BRPI0907457A2 (pt) Absorventes
BRPI0915562A2 (pt) tamis melhorado
EP2259958A4 (fr) Timonerie de direction
BRPI0915442A2 (pt) tamis melhorado
FI20105881L (fi) Hydrosykloni
DK2252471T3 (da) Blyant
BRPI0922728A2 (pt) combinação de herbicida-antídoto
UA19310S (uk) Автомобіль
FI20085942L (fi) Kaivo
UA19314S (uk) Автомобіль
ES1067844Y (es) Burlete mejorado
FI8167U1 (fi) Parannettu savuhormi
UA19299S (uk) Фірмовий бланк
ES1069154Y (es) Mecanismo escurridor de fregona
CN301233354S (zh) 汽车
CN301156734S (zh) 汽车
CN301012228S (zh) 汽车
CN301144321S (zh) 汽车
CN301066641S (zh) 汽车
TH105018B (th) รถยนต์
UA18988S (uk) Автомобіль
UA18171S (uk) Автомобіль

Legal Events

Date Code Title Description
CA Change of address
CD Change of name or company name
PLFP Fee payment

Year of fee payment: 8

PLFP Fee payment

Year of fee payment: 9

PLFP Fee payment

Year of fee payment: 10

PLFP Fee payment

Year of fee payment: 11

PLFP Fee payment

Year of fee payment: 12

PLFP Fee payment

Year of fee payment: 13

PLFP Fee payment

Year of fee payment: 14

PLFP Fee payment

Year of fee payment: 15

PLFP Fee payment

Year of fee payment: 16

PLFP Fee payment

Year of fee payment: 17

PLFP Fee payment

Year of fee payment: 18